Protein Alignment Rab35 and RAB11B

DIOPT Version :10

• Sequence 1: NP_608373.1
• Gene: Rab35 / 33014
• FlyBaseID: FBgn0031090
• Length: 201
• Species: Drosophila melanogaster
• Sequence 2: NP_004209.2
• Gene: RAB11B / 9230
• HGNCID: 9761
• Length: 218
• Species: Homo sapiens
• Alignment Length: 210
• Identity: 87/210 - (41%)
• Similarity: 132/210 - (62%)
• Gaps: 14/210 - (6%)

  Fly     5 FDHLFKLLIIGDSGVGKSSLLIRFSDDTFSGSYITTIGVDFKIRTVDIEGMRVKLQIWDTAGQER 69
            :|:|||:::|||||||||:||.||:.:.|:....:||||:|..|::.::|..:|.||||||||||
Human     8 YDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQER 72

  Fly    70 FRTITSTYYRGTHGVIVVYDVTNGESFANVRRWLEEIQNNCDV-VKKVLVGNKNDDPDRKVVITE 133
            :|.|||.||||..|.::|||:....::.||.|||:|::::.|. :..:|||||:|....:.|.|:
Human    73 YRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTD 137

  Fly   134 DAQRFAKQMDIELFETSAKDNINVENMFLSI---------TRQVLDHKLR-TSPNEQQKDTLHLK 188
            :|:.||::.::...||||.|:.|||..|.:|         .:|:.|.... .||.....| :.:.
Human   138 EARAFAEKNNLSFIETSALDSTNVEEAFKNILTEIYRIVSQKQIADRAAHDESPGNNVVD-ISVP 201

  Fly   189 PNPKGSKGGK--CCR 201
            |...|.|..|  ||:
Human   202 PTTDGQKPNKLQCCQ 216

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab35	NP_608373.1	Rab35	3..201	CDD:133310	86/208 (41%)
RAB11B	NP_004209.2	Rab11_like	9..173	CDD:206660	76/163 (47%)
		Switch 1. /evidence=ECO:0000305|PubMed:16545962, ECO:0007744|PDB:2F9L, ECO:0007744|PDB:2F9M	36..47		4/10 (40%)
		Switch 2. /evidence=ECO:0000305|PubMed:16545962, ECO:0007744|PDB:2F9L, ECO:0007744|PDB:2F9M	67..86		14/18 (78%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	184..218		9/34 (26%)