Protein Alignment Rab35 and Rab8a

DIOPT Version :10

• Sequence 1: NP_608373.1
• Gene: Rab35 / 33014
• FlyBaseID: FBgn0031090
• Length: 201
• Species: Drosophila melanogaster
• Sequence 2: NP_446450.2
• Gene: Rab8a / 117103
• RGDID: 621144
• Length: 207
• Species: Rattus norvegicus
• Alignment Length: 199
• Identity: 101/199 - (50%)
• Similarity: 141/199 - (70%)
• Gaps: 15/199 - (7%)

  Fly     1 MARGFDHLFKLLIIGDSGVGKSSLLIRFSDDTFSGSYITTIGVDFKIRTVDIEGMRVKLQIWDTA 65
            ||:.:|:|||||:||||||||:.:|.|||:|.|:.::|:|||:||||||::::|.|:||||||||
  Rat     1 MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTA 65

  Fly    66 GQERFRTITSTYYRGTHGVIVVYDVTNGESFANVRRWLEEIQNNCDV-VKKVLVGNKNDDPDRKV 129
            |||||||||:.||||..|:::|||:||.:||.|:|.|:..|:.:... |:|:::|||.|..|::.
  Rat    66 GQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQ 130

  Fly   130 VITEDAQRFAKQMDIELFETSAKDNINVENMFLSITRQV---LDHKLR-TSPN----------EQ 180
            |..|..::.|....|:..|||||.||||||.|.::.|.:   :|.||. .||.          ||
  Rat   131 VSKERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGNSPQGSSHGVKITVEQ 195

  Fly   181 QKDT 184
            ||.|
  Rat   196 QKRT 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab35	NP_608373.1	Rab35	3..201	CDD:133310	99/197 (50%)
Rab8a	NP_446450.2	Rab8_Rab10_Rab13_like	6..172	CDD:206659	89/165 (54%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		6/13 (46%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		14/16 (88%)