Protein Alignment: Hers and bahcc1b

• Sequence 1: NP_001245771.1
• Gene: Hers
• FlyBaseID: FBgn0052529
• Length: 2529
• Species: Drosophila melanogaster
• Sequence 2: XP_009305095.1
• Gene: bahcc1b
• ZFINID: ZDB-GENE-100716-2
• Length: 2688
• Species: Danio rerio
• Alignment Length: 3132
• Identity: 560/3133 (18%)
• Similarity: 936/3133 (30%)
• Gaps: 1122/3133 (36%)

  Fly    14 QRSTATAAAAAAAAAAAATASSTQGKKRPGKQTKASGGGGDEADDKKSASKTDSAAKKPAKDPTG 78
            :|......||:....|..|.....|..:|||.                   ..|....|....:|
Zfish    15 ERGALVHRAASRITPAGHTTVQHPGHFQPGKY-------------------YPSHIPMPPHSGSG 60

  Fly    79 SSGVSTATTEG---GAGNGGGKQTTSTTTSSTSS--------TTAPS--------------ASAS 118
            ..|.|:|:..|   .:..|......|...||.||        :||||              ..:.
Zfish    61 LIGNSSASFMGTFLASSLGSPPSHPSGPPSSPSSPPYRSGPHSTAPSQIWFPHSHEAPGYPRFSG 125

  Fly   119 ASASNSLKLSPEERHEDGKARAINKMLKSLDIKIHGFDNLLPSGEERLNDGVLKSSISENVKTKS 183
            :.|...|.:||.:.|  |.:..:....:..|.:...:...|||....|       |.:.::...|
Zfish   126 SLAPTFLPMSPLDHH--GNSSVLYGQHRFYDTQKDFYLRSLPSQPHLL-------SANHSLPPLS 181

  Fly   184 RAAAVKVISSLNPGKMPPVKRVRPSPEPVREK------VAEKPA-----EKVLDKEKPKAEQQIT 237
            |.|....:.|.:        |.|.....|.:|      |||:..     ||...|::.|.::...
Zfish   182 RTAPAHPLDSCS--------REREPGSTVSQKSSKETGVAERRVGPGGKEKEKSKQESKQDRHHG 238

  Fly   238 PPPA-------PEESPASKVPKKTVQQAKKAKVESSLVQATVLTTTSAATSAPSSASTSKHTSTK 295
            ||..       |:..|      :.::...:.|.:...:.:.:|:|.:...|.|.:|:.....|..
Zfish   239 PPTLHHHHQHHPQHHP------QGLEDDFRHKDDPKHLSSCLLSTKTQNGSDPGAATRGSLPSCV 297

  Fly   296 NP-------GKKSAHSEQMPKKELSKLAKMGKPKKEANLVKSTARLPDSNTESVQMELEEIVSTP 353
            .|       |::::......|:.:|...::.:|..:.  ::.:|.|..::            ..|
Zfish   298 GPGASSLGTGRQTSGDSHCCKEGVSGEMRISEPASDC--LRHSAMLGHAH------------PMP 348

  Fly   354 TVTPTPSATPTAT---------------------------PTPTATPTLTPTPTATRTRTPTPTL 391
            ...|.|....:|.                           |.|...||.........:....||.
Zfish   349 YSMPPPLGLGSAVGGSWLHPNHPHHHHPHHPHAELFCPPPPAPLTMPTAQEKSLGRDSEVTGPTF 413

  Fly   392 TPTPTPTSTPSS----------TAIAAGQPAPPPPPPGGAPKQRPKVKYTKTSAGSKGRMQQALN 446
            .|:..|.....|          ..:..|..|     .||             |||.:
Zfish   414 VPSVGPLGDKISGPFQLGNHHCRGVGGGMIA-----VGG-------------SAGKE-------- 452

  Fly   447 QKAPAASWSGAKDIYDFKSGSEDEEPIKMVLPSLKELREFSDEDNKPLKLFERQAEKTKVQVQDE 511
            .|.|..|.||::              ...:||                        :...|.:..
Zfish   453 TKTPERSSSGSR--------------AANLLP------------------------QNSCQRKSS 479

  Fly   512 EEQPLVKKEEKPPSEKEVKVKSKEKEKEKEKDVDPLSNAQQSEPAAKHTTSTSTTSTTSITSVKK 576
            ::|....|.:|.|                  |..|..:.:.:|........|.:..:.|:.|.::
Zfish   480 QQQHAYGKADKSP------------------DWPPGPHLRTNEVQHSQNQHTHSARSCSLDSSEE 526

  Fly   577 QAKRKIATPMPSSAGRKKKTVGKGKAAAAKEPPPSGSSAESSSSEDERKLSAYSGPKRHRMASLN 641
            ....:.:.|..:..|.:.|:     :..|..||....|              :|||.....:...
Zfish   527 SDAFRPSLPQGTKGGHQAKS-----SIYASTPPFRDCS--------------HSGPSNRASSEGK 572

  Fly   642 ALAKVQCLYENESRTA---HELGLSKATQQPPRI---------RTLD-------------GS--- 678
            ...:|:|..::..|.|   |:...:....|.|.:         |.:|             |:
Zfish   573 GATEVECTQKSSQRVARIRHQQHRASTGGQGPEMEPNSTTQDKRKMDMESASQGYGGNRTGTHPS 637

  Fly   679 ----------DDDNHKDSPRHG---DTDR-DKGSVSPPHTSAAPPAAPIAP--PKEAEPRRELRY 727
                      |::.||.....|   .|.| |:|.: ||.|  ||..|.:.|  |:....|..::|
Zfish   638 WEVRGPQPRPDEEPHKAYNSLGAASQTSRVDQGPL-PPLT--APQEATLGPQGPESNAMRNLMKY 699

  Fly   728 VP------------GGRG-------VGKHWE----FDSDSETEELQLQ---QTLPPVKKKKLPKK 766
            ..            ||.|       .|:..|    .|.........||   |||||
Zfish   700 SSQQPLLFTQKSPFGGLGCLKQGAVAGERSERNERSDKSGNGSSCALQEGKQTLPP--------- 755

  Fly   767 APPKKVASSETDAKRKKKSVQVEESDDEEAKEKEKEKEKP-----------KPPKQLPKKRKT-A 819
                :.|||..:.:|.::    ...|..||:.:.:.::.|           :||.:||....| :
Zfish   756 ----RRASSSGENERSER----VGKDSGEAQGEGEVRQPPVGIAVAVARQREPPCRLPDGHPTHS 812

  Fly   820 FTEELIGDYKGILARKRMASLNASAIVAATYEVERHLDKNLASDCSSFESYDELDTMPTTTSKVT 884
            ....::...||              |....|.:||.:|:.
Zfish   813 HHSRVMPSMKG--------------IGHPMYPLEREMDEE------------------------- 838

  Fly   885 SAAAIKTEVIHIKKEPKESKESLRERERERESERRRERDN------ELKDSTVGKMSSHSIIEES 943
                        :|...|.:..|...:||||...|..:|.      ....|..|.::||.|:...
Zfish   839 ------------RKRVCEEQLGLSPFDRERELLLRENKDRVEFARIHPSSSCHGDLTSHLIVPGG 891

  Fly   944 NDSKYSKETKETNTDTTITTTGYRDSAASTKDAKDCSRPTSSSVVIVQDTDVTITGVYVNASNGA 1008
            :.                  .|...||.:..........|.|            ..:::..|.|.
Zfish   892 SQ------------------LGTEPSAHAHPTHHHWMPRTGS------------PSLWMGHSYGL 926

  Fly  1009 AQEAYCKMQYRVQSSVTEERVLRPGSVEPPKSYTPLSALSSMLPPGASSGLSEAHSSPPLPVHAA 1073
            :.                                  :||...|.||.|:.: .:...|.||:...
Zfish   927 SH----------------------------------AALHQNLTPGFSTTM-PSPLQPVLPLPQD 956

  Fly  1074 PTGPHVLLPGEHLSAGMYHAPDLGLHTEHALPDHHGPPPPSYAAAAAAAAAAAAYHAHQLAPGGG 1138
            |:...|:||.|.::....|..|        :.:..|..||.|.|.                   |
Zfish   957 PSAALVVLPTEPVAHPATHHLD--------VMEQQGLWPPVYGAR-------------------G 994

  Fly  1139 GVLHMHH-------------------QHQYAAH-------AAHAHHYQQ-------------AAE 1164
            ...||.|                   |||:..|       .||.|.:.|             .:|
Zfish   995 PTSHMQHPAVYSRSQFLRQQELYALQQHQHQQHRAAQAMELAHRHSHSQRKPEDPPIDLVEGPSE 1059

  Fly  1165 YHG-----------GPPPPPHHY--GG-----------PPPQGHYGPPPGAPVPVP---VAVPNT 1202
            .|.           .|.|||...  ||           |.|:.|....|..|.|.|   ||.|.:
Zfish  1060 PHAPKHTKPFSVGPSPKPPPSSSSPGGCASRLSPCCRSPAPRSHLKSTPCTPCPEPSPAVAAPRS 1124

  Fly  1203 VTVPP--------------ERCDVGSPPPSYRASAYP--PPSSVGMPPPTLGGGSSAFCAPSP-- 1249
            ..:.|              ::...|.||..|..|..|  ||   |...|.:..|...  .|||
Zfish  1125 PALSPHSTPHHLPKPAESQDKRGEGQPPQDYPQSLEPDLPP---GYTYPAIAMGYKG--GPSPQE 1184

  Fly  1250 ---LHHHQHQHQQPGPGVGPPHHDPSGYYQPAGPLISPHVIAAPPPPAQVKK----------LQE 1301
               ..|...:.:|..|....|...|   ..|.|.  .|........|.::.|          :.|
Zfish  1185 VQLAEHADLEAEQAEPAEPAPRPHP---LSPKGE--EPVCHTGVGSPIRISKEIEDVEEEGGVIE 1244

  Fly  1302 EDGPVSAAGSPTQLQQQQAAAEAAAAAA----DQAAAQSQSQSQG-------------------- 1342
            |||.|........|.|......:..:.|    |:|.|...||:.|
Zfish  1245 EDGQVDEGQVDATLSQTSLCPTSDTSVAEPFSDKATAIPNSQTCGIVSPAPAEENNERDMDLQVP 1309

  Fly  1343 --------QSHGHAHSHAHN-----------PQQAQHPP-QPQP--------YPAGAV-----AA 1374
                    |:........|:           |..:..|| .|.|        ||...:     ..
Zfish  1310 MIAPLTTTQNLQSVEPTKHDLDRTVEDGCTPPTNSSTPPLSPCPVPSDLGNQYPGSCIWSLELLI 1374

  Fly  1375 AAAAAAAHQGVPYSRSMHAAQMHYSTGYPPNYYAPYPG-------------------------EV 1414
            |||..|...          |:|..|.....|..||..|                         ::
Zfish  1375 AAALCATRD----------ARMAMSVPVSGNAVAPNYGIELLSELAELEQSQQQRNNTGENDDDM 1429

  Fly  1415 MCYSPPTYPPYFSSKVYQ--PSHPAH------------------PAAHPQGPPP----------- 1448
            :.:...:.....:::..:  |..||.                  |.:.|..|..
Zfish  1430 LTFDLQSLATLAAARALELAPPIPADSTPPLRRILNLRKKCKWTPRSEPVCPVKATMETLDQEEL 1494

  Fly  1449 ------PGAYRRYPYYQH--AGPPPPHELYEQQPPPPPVSSG--------SVSGPAQQQP-PTSS 1496
                  ....|||...|.  |.....|:..:::....|...|        |.|.|    | ||.:
Zfish  1495 AMRVRLAELQRRYKEKQRELAKLQRKHDHQKEETARSPARRGPGRPRKRKSTSAP----PIPTDA 1555

  Fly  1497 PASVGAAGAGTA-GAPSGSQLVPAHQQQHQQQHLEHYPGPPSYY-------AGYSPGG------- 1546
            |..|.:||||.. |..:...|.....::.:::.:   .|.|.::       |...|.|
Zfish  1556 PKKVKSAGAGAGPGLMTAEDLAGGGDRKRKKKRM---TGGPYHHLTSTQMKAHCRPRGRPRLLST 1617

  Fly  1547 -----GASAGQCYTRGLQGP-------YMEYPPQCPCPMPQSCPKNVHTGPHIGSNIISNIDQSS 1599
                 ..|..:...:..:|.       :.|...|...|..||..:.     |..:|.......::
Zfish  1618 KFKQKACSQLKQKAKAKRGSRLVNLLCHRESKTQSTVPEHQSAKEE-----HAHNNKTGEQGDTA 1677

  Fly  1600 SCSSSMLLSATSNSNIGGGSSSSSSSSSSTTLPA------CSSATTTTTASALTTSRGPVKNVTP 1658
            ...:::...:....::....:.|.:..|||.||.      |::|.|.:...|  |.:|    ::.
Zfish  1678 GSGTAVQQDSDGKRSVMKRGARSKAILSSTPLPTRTQQLLCNTAMTDSKLEA--TEKG----ISD 1736

  Fly  1659 NNSNSSG-HTSTNSCRSSNNSNNSSN-------SSCQTIEMTSWATAATNTTSTTATTATTGTQC 1715
            ......| :.|........|.::...       |.|..:::.:...|..
Zfish  1737 TEEEDDGIYDSEEGAEGIKNLSSKEQLSGAGRPSQCSIVKLEANQKAKN---------------- 1785

  Fly  1716 QMLVKTELKG---ENPQVTKMQYEAHVMPPPTPPESYCASDEKLLDDQEQEAELELRLRLGLGLE 1777
                |||.:|   .|..|||.:.:..  ..|..|...||      |....|.:.:.||   .|.:
Zfish  1786 ----KTERQGFGSMNVSVTKEEMKRR--KAPCRPAQVCA------DHNHSELDEDRRL---TGPK 1835

  Fly  1778 KSHGGQQHIEAYD-----LTCSTPPPVTVPQAAAV--PRKA-----------------RI----- 1813
            ...|.:::  .:|     .|..||...|..::|.:  .||:                 ||
Zfish  1836 WREGSREN--TFDHTRVLKTSPTPRERTTRKSAVLLGKRKSCWLQALSSQYDDISWSRRIRNKQQ 1898

  Fly  1814 --GKSMAREM-VYAAQQ--QLLPEKQLKQPKEAAAKLEAEPEM---------PFVLKAEIKAE-T 1863
              |::::|.: .:||.:  |:..:....:.:|...:.|.|||:         ..:|..||..: .
Zfish  1899 AKGRAVSRLLESFAADEGFQIDDDSSFSEGEEEEEEEEEEPELMGSALPALPNCILTKEILRDGL 1963

  Fly  1864 KIKIEHDGEA--QASTHISQLPDLKPTIKTEPEQELEQEAASVPSV---------AKTEPQPE-V 1916
            |:.|..:.|.  .|..|...|||:...:       :|.|..:.|.:         |..:.||| |
Zfish  1964 KVLISKEDELLYAAYVHTLDLPDIYSVV-------VEGERGNRPRIYSLEQLLQEAVLDVQPETV 2021

  Fly  1917 EV------------ERE--------QQEPPVDEEQQPTPGGSKQRFNLLALSSGNKKTKTNNSYK 1961
            |.            ||.        ::..|.:|:::    ||.    ::....|::...:.:|.:
Zfish  2022 ETLMAGTRVCAYWSERSRCLYPGYVRRGGPGEEQKE----GSV----MVEFDDGDRGWISLSSIR 2078

  Fly  1962 SL-----IKQAEPKSYLCPGRRFIRRHGRAPAKYVK---RRQMILTQRQQQRMRLQRREQQQQRR 2018
            .|     :..|||                :||..:.   ||:...||.:    ..|:.:...:|.
Zfish  2079 CLPPGYQVHCAEP----------------SPAHLISPSCRRRKTSTQEK----ITQQADASNERS 2123

  Fly  2019 QQREAAAEVVAGAVVTPSLAGNPIEQAGSEVSIVKDQAPNSSATPSASPKRARP----------- 2072
            ...|.....|......|. :.|...::|:..::.:..:|..| .|.|:..|.:|
Zfish  2124 SNTEPRKSAVKAKPGRPK-SVNASSKSGASENVTETASPLLS-WPVATMSRRKPSMDLFQFNGLT 2186

  Fly  2073 ----RKQEIAALHLLEGLDTTLSRGYFS------------------------------------- 2096
                :.:|.....||....||.::|.||
Zfish  2187 KKALKGKESDMFPLLSSTMTTPAKGIFSTSFEVDSFSSIANGCTSFGNQQLAPGLPPSHKVVPGS 2251

  Fly  2097 -----------------------------------DPELNHSSRKQAPTAVGGLYAASSPLTTAT 2126
                                               :|||..|.|.:......|:    ..||:..
Zfish  2252 RCRKIGDRKEFLVKLDHEGVTSPKTKNGKALLLLGNPELQRSGRMEKGFGAKGI----GELTSTM 2312

  Fly  2127 DHR--------GKQTTAE-KRSKSETKKPPSG----ESSESGLPC-----------------KKP 2161
            .:.        .|:.:.. .:..|:.:|.|.|    |.::.|..|                 ::.
Zfish  2313 GYSQSVLLVKDAKRNSCHLLKGSSDMRKHPQGLGLSEYTDYGPNCHSDCLSSYSDMDEDEDEEED 2377

  Fly  2162 RKEPAGKVKGKGKKTTAGAAATTIASTAETQTEAVNAITASNQETNNNEYQTADLQAQKFRECPA 2226
            .:..|.:..|:.....:.:::::.:|:|.:.....::...|:.  |::.|.:.:.:|.:.
Zfish  2378 ARRAAMRTTGRFLSRLSVSSSSSGSSSASSSGSLSSSSVCSSD--NDSSYSSDEEEASRL----- 2435

  Fly  2227 VTDAKVAGTATSTSTASQQQNQQHSD-----EQHQFLVPSQPATASATAALAAT-PPPSRQGQAT 2285
                .:.|..:|..|..||  |||||     .:|.|...:...:.|..|..::| .||.|:..|.
Zfish  2436 ----LLQGCLSSHHTLLQQ--QQHSDPPTAPPRHTFGAKTMSISNSKAAVNSSTGKPPKRKEIAN 2494

  Fly  2286 HTKRTRSRCKFGNRKRQRHRPGGVSYELDVTQPPATKANVVPKWNNGWMWAGKAFQGAVFLNSDD 2350
            .:...:|:......|:|:         :..::.|...:..:| ....|.|:|...|.........
Zfish  2495 SSSVVQSKSSKDFPKKQK---------MQSSEGPPNSSAFMP-GRQLWRWSGNPTQRRGLKGKAR 2549

  Fly  2351 PLVLRTCYPAMRHVEG-DIIRIRDCVLLKANEDNELPYVAKVAHLWQNPEDGEMMMSLLWYYRPE 2414
            .|.    |.|:  |.| |.:|:.||.:..:.....||::.::..||:: ....|::.:.|:|.||
Zfish  2550 KLF----YKAI--VRGKDTVRVGDCAVFLSAGRPHLPFIGRIESLWES-WSSNMVVKVKWFYHPE 2607

  Fly  2415 HTDQGRQRNDCPDEVYASRHRDHNSVACVEDKCYVLTFSEYCRYRRRLRAAEEDVEDVSIV---- 2475
            .|..|::..|....:|.|.|.|.|.|..:..||.|::.:||.|. .|:|....:.:|:..:
Zfish  2608 ETKLGKRHRDGKHALYQSSHEDENDVQTISHKCQVVSRAEYERL-SRIRKPNSNGQDLYYLAGTY 2671

  Fly  2476 -PRRPSIATAPG 2486
             |....:.||.|
Zfish  2672 DPTSGQLVTAEG 2683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hers	NP_001245771.1	BAH_BAHCC1	2366..2519	CDD:240065	36/128 (28%)
bahcc1b	XP_009305095.1	BAH_BAHCC1	2560..2680	CDD:240065	32/122 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_KOG1886
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900