Protein Alignment Hers and LOC100331694

DIOPT Version :9

• Sequence 1: NP_001245771.1
• Gene: Hers / 33000
• FlyBaseID: FBgn0052529
• Length: 2529
• Species: Drosophila melanogaster
• Sequence 2: XP_005173894.1
• Gene: LOC100331694 / 100331694
• -ID: -
• Length: 841
• Species: Danio rerio
• Alignment Length: 938
• Identity: 211/938 - (22%)
• Similarity: 321/938 - (34%)
• Gaps: 306/938 - (32%)

  Fly  1734 QYEAHVMPPP--------------------TPPESYCASDEKLLDDQEQEAELELRLRLGLGLEK 1778
            ||::..:|.|                    ||.:|.|........|::|::..:.|..|     :
Zfish    53 QYKSQRLPTPPMNSVNERKRKLYPLRGRGGTPEDSLCCHVLLTRLDEQQDSTNKTREPL-----Q 112

  Fly  1779 SHGGQQHIEAY-DLTCSTPPPVTVPQAAAVPRKARIGKSMAREMVYAAQQQLLPEKQLKQPKEAA 1842
            |.|.:...... .|.......:.:.:.|...|....|..|.:......:.|   :|..::|:|:.
Zfish   113 SSGQEPRTRRLASLNAEALNSLLLEKPAGAMRTRAEGACMKKSWRRPEESQ---KKSWRRPEESQ 174

  Fly  1843 AKLEAEPEMPFVLKAEIKAETKIKIEHDGEAQASTHISQLPDLKPTIKTEPEQELEQEAASVPSV 1907
            .|....||                     |:|..|........|.|.:...|.:.:.......|.
Zfish   175 KKTWRRPE---------------------ESQKKTWRRPEESQKKTWRRPEESQKKSWKRPEESQ 218

  Fly  1908 AKTEPQPEVEVEREQQEPPVDEEQQPTPGGSKQRFNLLALSSGNKKT--KTNNSYKSLIKQAEPK 1970
            .||..:||...::..:.|   ||.|                   |||  :...|.|...::.|..
Zfish   219 KKTWRRPEESQKKTWRRP---EESQ-------------------KKTWRRPEESQKKSWRRPEES 261

  Fly  1971 SYLCPGRRFIRRHGRAPAKYVKRRQMILTQRQQQRMRLQRREQQQQRRQQREAAAEVVAGAVVTP 2035
            .     ::..||...:..|..:|.:      :.|:...:|.|:.|::..:|
Zfish   262 Q-----KKTWRRPEESQKKTWRRPE------ESQKKSWKRPEESQKKTWRR-------------- 301

  Fly  2036 SLAGNPIEQAGSEVSIVKDQAPNSSATPSASPKRAR-------PRKQEIAALHLLEGLDTTLSRG 2093
                 |.|.........::....|...|.||.||.:       ||:        |.||:|.....
Zfish   302 -----PEESQKKSWRKPEESQRKSWRRPEASQKRMKMDLCSPAPRR--------LAGLNTAALLN 353

  Fly  2094 YFSDPELNHSSRKQAPTAVGGLYAASSPLTTATDHRGKQTTAEKRSKSETKKPPSGESSESGL-- 2156
             .|.|..:|.|    ..|||                            ...||.:|...::..
Zfish   354 -ISSPSAHHRS----VCAVG----------------------------NDGKPTAGNDGKAIAWR 385

  Fly  2157 ---PCKKPRKEPAGKVKGKGKKTTAGAAATTIASTAETQTEAVNAITASNQETNNNEYQTADLQA 2218
               .|:.|..:.:..|..|||..   .::.|.......|...:...          ..:|||::.
Zfish   386 AIKLCRHPSHQESICVVCKGKSL---ESSPTFQEDPGYQPHGILGY----------PIKTADMRT 437

  Fly  2219 QKFRE----------CPAVTDAKVAGTATSTSTASQQQNQQHSDEQ------HQFLVPSQPATAS 2267
            ...:|          ||||...:.   .........||..:.|:||      |:.::|:.|...|
Zfish   438 VSVKEEHAEPVQCCCCPAVGAVEF---CHHLPMFLHQQAYRESEEQPVASIRHECVLPAPPLALS 499

  Fly  2268 ATAALA--------ATPPP---SRQGQATHT---------------------------------- 2287
            .....|        :.|.|   :|....|||
Zfish   500 HPCLCAEPCYYIHISHPGPTAAARPLPCTHTHCCPRGVSKLLPATGLPHPHPAYCCLCPAARLPY 564

  Fly  2288 -----KRTRSRCKFG----------------------------------------NRKRQRHRP- 2306
                 ..|...|.|.                                        |.|...|||
Zfish   565 TYLTLPETACSCSFSCSTSRHSSRTEAPPDAPALLLSPGCPSMPLVNRSARECPQNPKPSGHRPL 629

  Fly  2307 ---------GGVSYELDVTQPPATKANVVPKWNNGWMWAGKAFQGAVFLNSDDPLVLRTCYPAMR 2362
                     |||.......:|.          .|||...|.:.|..:.:..|:..|||.||.:::
Zfish   630 RTTRRLRPAGGVLRRRSTRRPD----------TNGWRPVGASTQRELLMAGDEQTVLRQCYDSVQ 684

  Fly  2363 HVEGDIIRIRDCVLLKANEDNE-LPYVAKVAHLWQNPEDGEMMMSLLWYYRPEHTDQGRQRN-DC 2425
            . :|::||:||.||||:....: ||||||::.||:.|..||:||||.||||||||..||..: .|
Zfish   685 R-DGELIRVRDTVLLKSGPRRKTLPYVAKISALWEEPRTGELMMSLFWYYRPEHTQGGRDPSMHC 748

  Fly  2426 PDEVYASRHRDHNSVACVEDKCYVLTFSEYCRYRRRLRAAEEDV-EDVSIVPRRPSIATAPGFPV 2489
            ..|::||||:|.|||||:|::||||..::|||:...:|...|.| |.|.:|| |.|..:.|..
Zfish   749 EKEIFASRHQDENSVACIEERCYVLPLAQYCRFCALVRRGVEGVCERVPLVP-RCSAGSVPNH-- 810

  Fly  2490 RTVPEHTNPELVMFCRRAYEFRTRRLLK 2517
            |::|...:|:||..||..|::|..|:||
Zfish   811 RSLPTGVDPQLVYLCRHVYDYRYGRILK 838

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hers	NP_001245771.1	BAH_BAHCC1	2366..2519	CDD:240065	76/155 (49%)
LOC100331694	XP_005173894.1	DUF4887	161..325	CDD:292845	40/239 (17%)
		BAH	687..792	CDD:295389	56/104 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	119	1.000	Domainoid score	I5750
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005583
OrthoInspector	1	1.000	-	-		otm25750
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46576
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.100