Protein Alignment DNAJB2 and CG5504

DIOPT Version :9

• Sequence 1: NP_006727.2
• Gene: DNAJB2 / 3300
• HGNCID: 5228
• Length: 324
• Species: Homo sapiens
• Sequence 2: NP_995932.1
• Gene: CG5504 / 48844
• FlyBaseID: FBgn0002174
• Length: 520
• Species: Drosophila melanogaster
• Alignment Length: 430
• Identity: 108/430 - (25%)
• Similarity: 166/430 - (38%)
• Gaps: 126/430 - (29%)

Human     4 YYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDRY 68
            ||..|.|.::|:..||||||.:.|.::|||.|.::.: |.:||:||:||||||||:.||..||.|
  Fly    66 YYATLGVAKNANGKDIKKAYYQLAKKYHPDTNKEDPD-AGRKFQEVSEAYEVLSDEQKRREYDTY 129

Human    69 GR--EGLTGTGTG-PSRAEAGSGGPGF--TFTFRS---PEEVFREFFGSGDPFAELFDDLGP--- 122
            |:  |.:...|.| |.....|.|..||  ::.|||   |||:||:.||.|:.....|||...
  Fly   130 GQTAENIGRQGGGFPGGGAGGFGPEGFSQSWQFRSSIDPEELFRKIFGEGNFRTNSFDDFADSKF 194

Human   123 -FSELQNRGSRHSGPFFTFSSSFPG-HSDFSSSSFSFSP--------------------GAGAFR 165
             |.:.|.....     .||:.:..| :.|.:.:.....|                    |.| |.
  Fly   195 GFGQAQEMVMD-----LTFAQAARGVNKDVNVNVVDQCPKCAGTKCEPGTKPGRCQYCNGTG-FE 253

Human   166 SVSTSTTFV------------------------QGRRITTRRI-------MENGQ---------- 189
            :|||. .||                        :||.:..|::       :||||
  Fly   254 TVSTG-PFVMRSTCRYCQGTRQHIKYPCSECEGKGRTVQRRKVTVPVPAGIENGQTVRMQVGSKE 317

Human   190 ---------------ERVEVEEDGQLK--------SVTINGVPDDLALGLE---------LSRRE 222
                           |..:|..|..:.        :|.:.||.:|..:.:|         :.|.:
  Fly   318 LFVTFRVERSDYFRREGADVHTDAAISLAQAVLGGTVRVQGVYEDQWINVEPGTSSHHKIMLRGK 382

Human   223 QQPSVTSRSGGTQVQQTPASCPLDSDLSEDEDLQLAMAYSLSEMEAAGKKPAGGREAQHRRQGRP 287
            ....|.:...|........:.|....|.:.   :||:..:.:|:|.  ..|.......:|:.|..
  Fly   383 GLKRVNAHGHGDHYVHVKITVPSAKKLDKK---RLALIEAYAELEE--DTPGQIHGIANRKDGSK 442

Human   288 KA---QHQDPGLGGTQE----GARGEATKRSPSPEEKASR 320
            :|   ..::||.|...:    .|...|:|..|..|:...:
  Fly   443 QATAGASEEPGAGAAAKASAAAAGSGASKPGPGAEKSEGK 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAJB2	NP_006727.2	DnaJ	3..>110	CDD:223560	53/113 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	70..90		6/22 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	218..324		21/110 (19%)
		CAAX motif. /evidence=ECO:0000269|PubMed:12754272	321..324		108/430 (25%)
CG5504	NP_995932.1	DnaJ	63..437	CDD:223560	97/383 (25%)
		DnaJ	65..127	CDD:278647	31/61 (51%)
		DnaJ_zf	227..287	CDD:199908	9/61 (15%)
		DnaJ_C	288..409	CDD:199909	18/120 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910