Protein Alignment Abcd3 and PXA2

DIOPT Version :10

• Sequence 1: NP_608354.1
• Gene: Abcd3 / 32992
• FlyBaseID: FBgn0031069
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_012733.1
• Gene: PXA2 / 853647
• SGDID: S000001671
• Length: 853
• Species: Saccharomyces cerevisiae
• Alignment Length: 711
• Identity: 218/711 - (30%)
• Similarity: 346/711 - (48%)
• Gaps: 123/711 - (17%)

  Fly    33 MSNKKRKPGYE----------DKIQYTIAEKK-----------DKKAGKAHVN-------SVFFK 69
            :.|||.:.|.|          .|.:.||..|.           ||::...|..       ...||
Yeast    51 LENKKIEEGKETAVDREEDESSKEELTIVSKHSTDSEDGAIIIDKESKTNHKGGERKGKVDFLFK 115

  Fly    70 QLRQLLPILIPGFWSVETGLLFLVAAALIGRSVSDIWMIQNATV---VESTIIHMNRTKFKTALL 131
            .|......||          ||:..|.|:  ::..:..::.||:   :.||::......|...||
Yeast   116 LLLHDKKCLI----------LFITQAILL--NIRTLLSLRVATLDGQLVSTLVRAQYANFTKILL 168

  Fly   132 -KY-LTALPAISVVTNVLKWSLGELKLRFRTNLTHHLYSQYL-NGYTYYKMSNLDNRIANADQLL 193
             |: :..:|| |.:.:::.::.....:.....::..|.|:|| |.:|:|.:::.:: ::.....|
Yeast   169 GKWMILGIPA-SFINSLISYTTKLCAVTINRKVSDFLLSKYLSNHHTFYSVASAES-VSEIQDNL 231

  Fly   194 TTDIDKFCESATDLYSNISKPVLDIFIYVYR-LTVNLGGKTPSILMLYLL-FAGVFLTRLRRPT- 255
            |.||..|..:::.|.:.:.||:||:.:..:: ||.|........|.|.|: :|...|.:|.:|.
Yeast   232 TKDIYTFSMNSSLLLNQLLKPMLDLILCSFKLLTSNTSVMGEGTLALGLIVYASNSLLKLIQPNF 296

  Fly   256 GRLTVEEQKLEGEFRYVNSRLITNSEEVAFYQGNVREKLTLLASYSKLRSHLRKFLEFRVSMGII 320
            .|||:....||..||.::|.|.:::||:|..:|..||...:..|:.:|...|.:.::.|....:.
Yeast   297 TRLTMASASLESWFRSLHSNLHSSNEEIALLRGQKRELENVDYSFYRLVLFLNREIKARAIYDVA 361

  Fly   321 DNIIGKYFASIVGFYAVSIPFFSENHP---LLSGENSGQRLQA-YYTYGRMLVKLAEAIGRLVLA 381
            ...:.||.....|....|||.|.:|.|   .|..:..|..:.| :.|..|:||..:.:|||.|..
Yeast   362 TAFVIKYTWGAAGLVLCSIPIFFKNKPSEDTLQLKEPGNDMTADFITNRRLLVTASSSIGRFVEL 426

  Fly   382 GREMSRLAGFTARMTELIKVLSDLNKGTYERTMVNGNNLAQNAVGSASSNFGPNKGIMCFEDNII 446
            .|.:.:|.|...|:.:...:| |.|||..|:...:                  .:.|:.::|:.|
Yeast   427 KRNIQQLRGIRLRLNKFNDLL-DANKGDDEKEPRD------------------ERCIVEYDDSRI 472

  Fly   447 RFEKVPLVTPNGDVLLQELSFEVKSGTNVLVCGPNGCGKSSLFRILGELWP-------TWGGKVT 504
            :||.:||:||...||:.||||::|.|.::|:.|||||||||||||||.|||       ....|:.
Yeast   473 KFENIPLITPANQVLVPELSFDLKHGNHLLIIGPNGCGKSSLFRILGGLWPIRATPNKNHQSKLI 537

  Fly   505 KPSRG-----KLFYVPQRPYM-TLGTLRDQIIYPHTRDDMRRLGHSDEDL--------MHYLDIV 555
            .|.|.     .:||:|||||| ...|.|:|||||.:.:..:...|:|.||        :..||:.
Yeast   538 MPRRTVDRDCAIFYLPQRPYMGNRSTFREQIIYPDSIEQFKERYHNDYDLGDADLIKILQLLDLE 602

  Fly   556 QLT------YLEQRENGLDS----------------------IEDWIDVLSGGEKQRIAMARLFY 592
            .|.      .|.||.:..||                      :.:|.:.|:.|.:||:||||::|
Yeast   603 DLVTENMSLLLAQRTSKNDSQQLSTEDNQSPCAIKVRDAFSIVRNWSEELTIGVQQRLAMARMYY 667

  Fly   593 HKPQFAILDECTSAVSVDVEGKMYSYCREVGITLFTVSHRKSLWAHHDYYLQFDGRGSYEF 653
            |||:||:||||||||:.::|.:||...:..||:|.:|.||.|||..|:|.|:|||:|.|:|
Yeast   668 HKPKFAVLDECTSAVAPEMEQRMYENAQNFGISLISVCHRTSLWHFHNYLLKFDGKGGYQF 728

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abcd3	NP_608354.1	3a01203	3..653	CDD:273360	217/709 (31%)
PXA2	NP_012733.1	3a01203	24..728	CDD:273360	217/709 (31%)