Protein Alignment CG14227 and TMPRSS11A

DIOPT Version :10

• Sequence 1: NP_608345.2
• Gene: CG14227 / 32978
• FlyBaseID: FBgn0031058
• Length: 286
• Species: Drosophila melanogaster
• Sequence 2: NP_872412.3
• Gene: TMPRSS11A / 339967
• HGNCID: 27954
• Length: 421
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 82/295 - (27%)
• Similarity: 126/295 - (42%)
• Gaps: 80/295 - (27%)

  Fly    33 RSLPTNAKLTWWNYFDSST---DIQAN------------------------PWIVSVIVNGKAKC 70
            |:||.||.....|...|||   .:||:                        ||..|:..:...:|
Human   151 RALPINASSVQVNAMSSSTGELTVQASCGKRVVPLNVNRIASGVIAPKAAWPWQASLQYDNIHQC 215

  Fly    71 SGSLINHRFVLTAAHCVFREAMQVHLGDFDAWNPGQNCSSGARLSNAYCVR-IDKKIVHAGFGKI 134
            ..:||::.:::||||| |::....|     .|    ..|.|.:::.....| :.:.|:|..: :.
Human   216 GATLISNTWLVTAAHC-FQKYKNPH-----QW----TVSFGTKINPPLMKRNVRRFIIHEKY-RS 269

  Fly   135 QAQQYDIGLLRMQHAVQYSDFVRPICLLINEPVAAIDRFQ--LTV----------WGTTAEDFRS 187
            .|::|||.::::...|.:||.:|.|||    |.|:.. ||  |||          .|.:..|.|.
Human   270 AAREYDIAVVQVSSRVTFSDDIRQICL----PEASAS-FQPNLTVHITGFGALYYGGESQNDLRE 329

  Fly   188 IPRVLKHSVGDRIDRELCTLKFQQQVDESQI-----CV-HTETSH-ACKGDSGGPFSAKILYGGT 245
             .||      ..|..::|.   |.||..:.|     |. :.|..: ||:||||||...:.|....
Human   330 -ARV------KIISDDVCK---QPQVYGNDIKPGMFCAGYMEGIYDACRGDSGGPLVTRDLKDTW 384

  Fly   246 YRTFQFGIIIFGLSSCAGL---SVCTNVTFYMDWI 277
            |   ..||:.:| .:|...   .|.|.||:|.:||
Human   385 Y---LIGIVSWG-DNCGQKDKPGVYTQVTYYRNWI 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:214473	69/242 (29%)
TMPRSS11A	NP_872412.3	SEA	49..149	CDD:460188
		Tryp_SPc	190..418	CDD:238113	71/256 (28%)