Protein Alignment CG14227 and Hpn

DIOPT Version :10

• Sequence 1: NP_608345.2
• Gene: CG14227 / 32978
• FlyBaseID: FBgn0031058
• Length: 286
• Species: Drosophila melanogaster
• Sequence 2: NP_001263198.1
• Gene: Hpn / 15451
• MGIID: 1196620
• Length: 445
• Species: Mus musculus
• Alignment Length: 279
• Identity: 79/279 - (28%)
• Similarity: 123/279 - (44%)
• Gaps: 53/279 - (18%)

  Fly    30 ECG-RSLPT-------NAKLTWWNYFDSSTDIQANPWIVSVIVNGKAKCSGSLINHRFVLTAAHC 86
            :|| |.||.       ::.|..|            ||.||:..:|...|.|||::..:|||||||
Mouse   180 DCGRRKLPVDRIVGGQDSSLGRW------------PWQVSLRYDGTHLCGGSLLSGDWVLTAAHC 232

  Fly    87 VFREAMQVHLGDFDAWNPGQNCSSGARLS-NAYCVRIDKKIVHAGF-----GKIQAQQYDIGLLR 145
             |.|..:|    ...|.  ....:.||.| :|..:.:...|.|.|:     ..|.....||.|:.
Mouse   233 -FPERNRV----LSRWR--VFAGAVARTSPHAVQLGVQAVIYHGGYLPFRDPTIDENSNDIALVH 290

  Fly   146 MQHAVQYSDFVRPICL------LINEPVAAIDRFQLTVWGTTAEDFRSIPRVLKHSVGDRIDREL 204
            :..::..:::::|:||      |::..|..:     |.||.| :.:.....||:.:....|..|:
Mouse   291 LSSSLPLTEYIQPVCLPAAGQALVDGKVCTV-----TGWGNT-QFYGQQAMVLQEARVPIISNEV 349

  Fly   205 CTLK--FQQQVDESQICV-HTETS-HACKGDSGGPFSAKILYGGTYRTFQFGIIIFGLSSCA--- 262
            |...  :..|:.....|. :.|.. .||:|||||||..:....||.|....||:.:| :.||
Mouse   350 CNSPDFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISGTSRWRLCGIVSWG-TGCALAR 413

  Fly   263 GLSVCTNVTFYMDWIWDAL 281
            ...|.|.||.:.:||:.|:
Mouse   414 KPGVYTKVTDFREWIFKAI 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:214473	69/238 (29%)
Hpn	NP_001263198.1	Hepsin-SRCR	79..187	CDD:462736	3/6 (50%)
		Tryp_SPc	191..428	CDD:238113	71/262 (27%)