DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14207 and HSPB2

DIOPT Version :10

Sequence 1:NP_728275.1 Gene:CG14207 / 32955 FlyBaseID:FBgn0031037 Length:192 Species:Drosophila melanogaster
Sequence 2:NP_001532.1 Gene:HSPB2 / 3316 HGNCID:5247 Length:182 Species:Homo sapiens


Alignment Length:69 Identity:30/69 - (43%)
Similarity:47/69 - (68%) Gaps:1/69 - (1%)


- Green bases have known domain annotations that are detailed below.


  Fly   109 DVSQYAPEEIVVKTVDQKLLVHAKHEEKSDTKS-VYREYNREFLLPKGVNPESIRSSLSKDGVLT 172
            |||.:.|:|:.|:|||..|.|.|:|.::.|... |.||:.|.::||..|:|..:|::||.||:|.
Human    79 DVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHDGILN 143

  Fly   173 VDAP 176
            ::||
Human   144 LEAP 147

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14207NP_728275.1 metazoan_ACD 96..177 CDD:107247 30/69 (43%)
HSPB2NP_001532.1 Crystallin <21..51 CDD:425732
alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins. 67..148 CDD:469641 30/69 (43%)
Blue background indicates that the domain is not in the aligned region.

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