Protein Alignment car and vps33a

DIOPT Version :10

• Sequence 1: NP_001259707.1
• Gene: car / 32947
• FlyBaseID: FBgn0000257
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: XP_012818531.1
• Gene: vps33a / 549689
• XenbaseID: XB-GENE-978483
• Length: 614
• Species: Xenopus tropicalis
• Alignment Length: 611
• Identity: 269/611 - (44%)
• Similarity: 382/611 - (62%)
• Gaps: 32/611 - (5%)

  Fly    11 RVNLQLLQEAACRELLQQLDRIEGSKVIVLDETMIGPLDLVTRPKLFADRGI-RLLALKPELHLP 74
            ||||.:|:||...||.:.||:..|||.||.||.:.||..|:.:..|..:..: ::..||......
 Frog    22 RVNLNILREAMRMELREFLDKCAGSKAIVWDEYLTGPFGLIAQYSLLKEHEVEKMFTLKSGPLPS 86

  Fly    75 REVANVVYVMRPRVALMEQLAAHVKAGGRAA-AGRQYHILFAPRRSCLCVSQLEVSGVLGSFGNI 138
            .:|.|:::.:|||:.||:.:|.:::...|.. ..|.::|||.||||.||..:|:..||||||.:.
 Frog    87 SDVKNIIFFVRPRLELMDIIADNIQREERGRFPQRDFYILFVPRRSILCEQRLKDLGVLGSFMHR 151

  Fly   139 EELAWNYLPLDVDLVSMEMPNAFRDVSVDGDTSSLYQAAVGLVQLQRLYGRIPKIYGKGEFAHRV 203
            :|...|.:|.|.||:|||..|||::..::.|.:||||||.||..||.|||.||:|.||||.|..|
 Frog   152 DEYRLNLIPFDGDLLSMESENAFKECYLENDQTSLYQAAKGLTTLQSLYGTIPQICGKGECARHV 216

  Fly   204 WEHAKQLGRDERTL---YNGDKGVVDQLILLDRSIDLLSPLATQLTYEGLIDEFYGIRQNKLTLP 265
               |..:.|.:|.|   .|....|.|.|:||||::|||:||||||||||||||.|||:.:.:.||
 Frog   217 ---ANMMIRMKRELGGSQNQITPVFDTLLLLDRNVDLLTPLATQLTYEGLIDEVYGIQNSHVKLP 278

  Fly   266 AENFPSDGALPGGGGSGPRVEESQSLLGDTEKKTILLHSGEQLYAELRNKHFNEVTKLLARKARE 330
            .|.|     .|...|.|     .:.|  .||.|.:||:|.|:||||:|:|:||.|..:|::||:.
 Frog   279 PEKF-----APKKQGEG-----GKDL--PTEPKKLLLNSAEELYAEIRDKNFNAVGSVLSKKAKI 331

  Fly   331 IHVQMHATSQDKSVQEIKSFVENLLPQLMAQKKATSEHTAIAGLLHEQVNAVRFADDLAAEQEFM 395
            |..........|:|.|||.||.. ||.:.|:|.:.:.||:||.|:.|...:..|.|:|..|||||
 Frog   332 ISAAFEGRHNAKTVGEIKQFVSQ-LPHMQAEKASLANHTSIAELIKEITTSEAFFDNLTVEQEFM 395

  Fly   396 VCADIDKPSAYIEDLIACRVELNRVLRLICMQCHAASGFKEKLLNHYKRELVHVYGLEVLLTISN 460
            ...|.||.:.||||.||.:..:.::|||:|:|....:|.|:|:|::||||::..||.|.:||:.|
 Frog   396 SGFDTDKVNPYIEDCIAKKDPIIKILRLVCLQSVCNTGLKQKVLDYYKREILQTYGYEHILTLHN 460

  Fly   461 LEKSGLLHLQTESR-AYSVLRKTLHLTVDDNVEIEPKDISYVHSFYAPLTARIVEHSLKPLGWQT 524
            |||:|||.||..|| :|..:||||.|.:||..|..|.|||||:|.||||:.|:.:..::| ||::
 Frog   461 LEKAGLLKLQASSRNSYPTIRKTLRLWMDDVNEQNPNDISYVYSGYAPLSVRLAQILVRP-GWRS 524

  Fly   525 LKSQINNLPGPTFEDFQAQLVGIGGRHTVTTVSEGSLLNVPRVVLVCFVGGCTFAEIAALRFLAA 589
            ::..:..||||.||:.|:...|:     :....:|.    .:|:||.|:||.|||||||||||:.
 Frog   525 IEEVLKILPGPQFEERQSLPPGL-----LKKRQQGE----NKVILVFFLGGVTFAEIAALRFLSQ 580

  Fly   590 QEDNNVEFLIATTKVVNKHSFLDSLM 615
            .||...|::|||||:::..:::.|||
 Frog   581 MEDGGTEYIIATTKLISGTTWIKSLM 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
car	NP_001259707.1	Sec1	36..613	CDD:460020	253/582 (43%)
vps33a	XP_012818531.1	Sec1	47..604	CDD:460020	253/582 (43%)