Protein Alignment car and Vps33B

DIOPT Version :10

• Sequence 1: NP_001259707.1
• Gene: car / 32947
• FlyBaseID: FBgn0000257
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_651395.1
• Gene: Vps33B / 43077
• FlyBaseID: FBgn0039335
• Length: 640
• Species: Drosophila melanogaster
• Alignment Length: 666
• Identity: 150/666 - (22%)
• Similarity: 263/666 - (39%)
• Gaps: 108/666 - (16%)

  Fly    14 LQLLQEAACRELLQQLDRIEGSKVIVLDETMIGPLDLVTRPKLFADRGI-RLLALKPELHLPREV 77
            ||..|..|..:|...|..|.|.|.::|:..:|.||:.|........:|| |:........|||..
  Fly     9 LQGFQLVAQEKLCSILCSIPGKKELILEPDLIKPLEHVVTASWLKLKGIQRIYKHDAAQSLPRSA 73

  Fly    78 ANV-VYVMRPRV----ALMEQLAAHVKAGGRAAAGRQYHILFAPRRSCLCVSQ--LEVSGVLGSF 135
            ..| :|::|..:    .|::||...........:.:.|||:..|  ||....|  ||.:|:.| .
  Fly    74 DQVHIYMIRSVLGTFQTLLKQLQPVASEEMPDISMKMYHIVCVP--SCYSYFQTLLEQAGLYG-L 135

  Fly   136 GNIEELAWNYLPLDVDLVSMEMPNAFRDVSVDGDTSSLYQAAVGLVQLQRLYGRIPKIYGKGEFA 200
            ..:....|:::..|..::|:|:||.:..:.:..:||.|...|..|..||.:.|:...|...|..:
  Fly   136 VQLHHFNWDFIYFDQGVLSLELPNLYECLYLQKNTSPLPAVAQSLRLLQMICGQPSLILSFGHHS 200

  Fly   201 HRVWEHAKQLGRDERTLYNGDKGVVDQLILLDRSIDLLSPLATQLTYEGLIDEFYGIRQNKLTLP 265
            .::.:.||.||:........|.|   ..:::||..|..:.|.|...|.||:.|.:
  Fly   201 SQLMQMAKTLGKLPAPTNPPDYG---GWLVIDRDKDYPASLLTPAIYAGLLLEVF---------- 252

  Fly   266 AENFPSDGALPGGGGSGPRVEESQSLLGDTEK---------KTILLHS-GEQLYAELRNKHFNEV 320
              ...|...|.....:..|.:..:.|.|...|         .:|.|:| .:::|.:.|.|.|.:|
  Fly   253 --EHSSGEILVDNSKNKIRSQRVELLQGKKSKIGVNSASKPCSIRLNSTSDEIYGDNRYKRFAQV 315

  Fly   321 TKLLARKAREIHVQMHATSQDKSVQEIKSFVENLLPQLMAQKKATSEHTAIAGLLHEQVNAVRFA 385
            :.|:..:.:.:.:::...: |..:.|:..:|...||:|...|.....|...:.::.:.:...|..
  Fly   316 SSLIHAQVKALGLELQKLN-DMQLDEMHDYVARKLPKLTELKSKVLRHLNASEIVIQMMGNFRKL 379

  Fly   386 DDLAAEQEFMVCADIDKPSAYIEDLIACRVELNRVLRLICMQCHAASGFKEKLLNHYKRELVHVY 450
            ..|  |::.:......:..:.|::|:....:....|||:|: .|...|...:.|..:.|...:::
  Fly   380 QTL--EEDILNNDSRKRLLSEIDELLTTDGQRFNTLRLLCL-LHHCVGVAPEELQIFARNYCNLF 441

  Fly   451 GLEVLLTISNLEKSGLL-HLQTESRAYSVLRKTLHLTVDDNVEI--------------------- 493
            |.:.|.....|.::||| .|..|.:|.:.|...|.|......|.
  Fly   442 GHQELGVFQQLSQAGLLPPLVVEKKAPTKLLSNLPLPKFQQTEFQANANRLKLLTSSGDGQDGGS 506

  Fly   494 ----EPKDISYVHSF-----YAPLTARIVEHSLKPLGWQTLKSQINNLPG-----------PTFE 538
                :...:....||     |.||.|::....||....:.|.|::..:.|           |...
  Fly   507 SSKSQSSGLQTCPSFVFNGTYIPLVAQLCSILLKINSAEELSSKLGMIEGLHLHLDSGKITPKAY 571

  Fly   539 DFQAQLVGIGGRHTVTTVSEGSLLNVP---RVVLVCFVGGCTFAEIAALRFLAAQEDNNVEFLIA 600
            ..|.:|.|:..:..           .|   |.:.|..|||.::|||||..|:|  :....:..:|
  Fly   572 ASQVKLNGVADQDM-----------FPLRLRNLFVFIVGGASYAEIAACDFVA--KLTGAQITVA 623

  Fly   601 TTKVVNKHSFLDSLMS 616
            :          ||||:
  Fly   624 S----------DSLMA 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
car	NP_001259707.1	Sec1	36..613	CDD:460020	138/639 (22%)
Vps33B	NP_651395.1	Sec1	31..634	CDD:460020	142/644 (22%)