Protein Alignment car and Vps33B

DIOPT Version :10

• Sequence 1: NP_001259707.1
• Gene: car / 32947
• FlyBaseID: FBgn0000257
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: XP_321664.4
• Gene: Vps33B / 1281712
• VectorBaseID: AGAMI1_012979
• Length: 684
• Species: Anopheles gambiae
• Alignment Length: 689
• Identity: 153/689 - (22%)
• Similarity: 282/689 - (40%)
• Gaps: 106/689 - (15%)

  Fly    15 QLLQEAACRELLQQLDRIEGSKVIVLDETMIGPLDLVTRPKLFADRGIRLLALKPELHLPREVAN 79
            |:.||    :|......|...|.::::..:|.||:.|........:||..:......:.|.:...
Mosquito    14 QIAQE----KLQHVFYSIPSEKDLIIEPALIKPLEHVCGASWLRKKGIDKIFKFDSKNPPPKRKQ 74

  Fly    80 VVYVMRPRV----ALMEQLAAHVKAGGRA----AAGRQYHILFAPRRSCLCVSQLEVSGVLGSFG 136
            .||::...:    ::::|::.:.......    ...:|||:|..|.........||..|:.|
Mosquito    75 FVYLITSSLLTFKSVLDQISGYQSQTSSMMEPDIRNKQYHVLVLPSVLASFEHLLEEEGLHG--- 136

  Fly   137 NIEEL---AWNYLPLDVDLVSMEMPNAFRDVSVDGDTSSLYQAAVGLVQLQRLYGRIPKIYGKGE 198
             |.||   .|::|.||..|:|:|:||.|.||.|..||:.|...|..:.....:.|:...::..||
Mosquito   137 -IVELYNFQWDFLLLDESLLSLELPNVFADVFVRKDTTPLGSIAQSIRIFNLVMGKPHLVFSLGE 200

  Fly   199 FAHRVWEHAKQLGRDERTLYNGDK---GVVDQ---------LILLDRSIDLLSPLATQLTYEGLI 251
            .|.::.....::...:|....|.:   |.|||         :::|||..|..:.|.|.:.|.||:
Mosquito   201 NAEKILHMVHRMEAAKRPNVGGKENAAGKVDQPEKEPEYSAMLILDRDRDYPACLLTPVVYCGLL 265

  Fly   252 DEFYGIRQNKLTLPAE-NFPSDGALPGGGGSGPRVEESQSLLGDTEKKTILLH-SGEQ--LYAEL 312
            .|...:....|.:..| |...:|.|       ..::|..:.....:::|..|. ||.|  :|.|.
Mosquito   266 LEIQPLNSGSLAVDGEYNKIKNGKL-------AFLQEQNAAAASKQQETTSLRMSGAQDMIYLEH 323

  Fly   313 RNKHFNEVTKLLARKAREIHVQMHATSQDKSVQEIKSFVENLLPQLMAQKKATSEHTAIAGLLHE 377
            |.:||:||..||:.:|:.:.::..|.:::..:.|:|.:|.:.||::.|.||...:|..:...:.|
Mosquito   324 RYRHFSEVISLLSAQAKALGLEGKAYTREMKLHEMKEYVTHKLPKVAAAKKELFKHLRLCETIVE 388

  Fly   378 QVNAVRFADDLAAEQEFMVCADIDKPSAYIEDLIACRVELNRVLRLICMQCHAASG--------- 433
            ::.| .|......|:..:...:..:...||.:|::........|||||:. |...|
Mosquito   389 EIGA-NFEKHQMIEESILTNTNRKQIMNYILELLSSDAHRYNTLRLICLY-HVTIGLTGEDMTRL 451

  Fly   434 -------------------FKEKLL----NHYKRELVHVYGLEVLLTISNLEKSGLLHLQTESRA 475
                               |:.:|.    |..|.:::....:..|.|...:|.:.|..|.|::..
Mosquito   452 MTGYLNAFGYRHLSLFHSLFQARLFPDTTNLSKTKILSQISIPTLKTPFQIEANKLKQLPTDAND 516

  Fly   476 YSVLRKT------------LHLTVDDNVEIEPKDI-SYV-HSFYAPLTARIVEHSLKPLGWQTLK 526
            .:....|            :..|...||....|.. ||| :..|.||..::.........:..|.
Mosquito   517 TATTATTPTTDRDGGLTGGVQSTGGGNVAAGGKTCPSYVFNGNYIPLVTQLTNLIFAASSFDNLN 581

  Fly   527 SQINNLPGPTFEDFQAQLVGIGGRHT---------VTTVSEGSLLN--VP---RVVLVCFVGGCT 577
            :::.:|.............|..|.||         ::..|....||  :|   :.:.:..|||.|
Mosquito   582 TRLGHLERLKVSGRSLTASGQPGDHTQCAPRSIKELSASSHKVALNQLLPFKEKTMFIFIVGGIT 646

  Fly   578 FAEIAALRFLAAQEDNNVEFLIATTKVVNKHSFLDSLMS 616
            :|||||...|  :.....:.::::.:::..|..::|:::
Mosquito   647 YAEIAACHLL--ERTIGAKIVLSSDRIIAGHDLIESVVN 683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
car	NP_001259707.1	Sec1	36..613	CDD:460020	147/663 (22%)
Vps33B	XP_321664.4	None