Protein Alignment Hs3st-B and Ndst3

DIOPT Version :10

• Sequence 1: NP_573370.1
• Gene: Hs3st-B / 32918
• FlyBaseID: FBgn0031005
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_112463.2
• Gene: Ndst3 / 83398
• MGIID: 1932544
• Length: 873
• Species: Mus musculus
• Alignment Length: 317
• Identity: 100/317 - (31%)
• Similarity: 150/317 - (47%)
• Gaps: 58/317 - (18%)

  Fly   102 PPAQTVTSSLDGAP-KYQLLRQQGLRPSRH------------LPDTLIIGVKKSGTRALLEFIRL 153
            ||||......:..| :...|.|......||            ||..|:||.:|:||.||..|:.:
Mouse   553 PPAQLAHKYFELFPDQKDPLWQNPCDDKRHRDIWSKEKTCDRLPKFLVIGPQKTGTTALCLFLIM 617

  Fly   154 HPDVRA------AGSEVHFFDR-HYQRGLRWYRHHMPYTIEGQIT----MEKTPSYFVTKEVPQR 207
            ||.:.:      :..||.||:| :|.||:.||....|  :...:|    .||:.:||.:::.|:|
Mouse   618 HPSILSNSPSPKSFEEVQFFNRNNYHRGIDWYMDFFP--VPSNVTTDFLFEKSANYFHSEDAPKR 680

  Fly   208 VYHMNPATKLLIVVRDPVTRAISDYTQAASKKADMKLFEQLAFVNGSYSVVDTNWGP-------- 264
            ...:.|..|::.::.||..||.|.|....|.:....|  :.:|    |.|:..  ||
Mouse   681 AASLVPKAKIITILIDPSDRAYSWYQHQRSHEDPAAL--KFSF----YEVISA--GPNAPWELRT 737

  Fly   265 -----VKIGVYARYLERWLLYFPLSQLLFISGERLIMDPAYEIGRVQDFLGLKRVVTEKHFY--- 321
                 :..|.||.::||||:|||..|||.|.|::|...||..:..||.|||    |:..:.|
Mouse   738 LQKRCLVPGWYANHIERWLVYFPPFQLLIIDGQQLRTTPATVMDEVQKFLG----VSPHYNYSEA 798

  Fly   322 --FNATKGFPCLFKSEARSTPHCLGKTKGRNHPHIDPGAIERLREFYRPFNNKFYQL 376
              |::.|||.|....|.::  .||||:|||.:|.:|..:...|..:||..|.:..:|
Mouse   799 LTFDSHKGFWCQLLEEGKT--KCLGKSKGRKYPPMDSDSRAFLSSYYRDHNVELSKL 853

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hs3st-B	NP_573370.1	Sulfotransfer_1	131..368	CDD:425820	88/265 (33%)
Ndst3	NP_112463.2	Heparan sulfate N-deacetylase 3	36..589		9/35 (26%)
		HSNSD	76..506	CDD:463450
		Heparan sulfate N-sulfotransferase 3	590..873		91/280 (33%)
		Sulfotransfer_1	595..846	CDD:425820	89/266 (33%)