back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hs3st-B and HS3ST6

DIOPT Version :9

Sequence 1:	NP_001259702.1	Gene:	Hs3st-B / 32918	FlyBaseID:	FBgn0031005	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_001009606.3	Gene:	HS3ST6 / 64711	HGNCID:	14178	Length:	342	Species:	Homo sapiens

Alignment Length:	285	Identity:	177/285 - (62%)
Similarity:	212/285 - (74%)	Gaps:	6/285 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 APPAQTVTSSL--DGAPKYQLLRQQGLRPSRHLPDTLIIGVKKSGTRALLEFIRLHPDVRAAGSE 163
            ||.....:||:  .|||...|....|   .|..|..||:||||.||||||||:||||||||.|||
Human    61 APAPSEPSSSVHRPGAPGLPLASGPG---RRRFPQALIVGVKKGGTRALLEFLRLHPDVRALGSE 122

  Fly   164 VHFFDRHYQRGLRWYRHHMPYTIEGQITMEKTPSYFVTKEVPQRVYHMNPATKLLIVVRDPVTRA 228
            .|||||.|:|||.|||..||.|::||||||||||||||:|.|:|::.|:|.|||::|||:|||||
Human   123 PHFFDRCYERGLAWYRSLMPRTLDGQITMEKTPSYFVTREAPRRIHAMSPDTKLIVVVRNPVTRA 187

  Fly   229 ISDYTQAASKKADMKLFEQLAFVNGSYSVVDTNWGPVKIGVYARYLERWLLYFPLSQLLFISGER 293
            ||||.|..||...:..|..|||.:| ...|||.|..|:||:||::|:.||.|||||..||:||||
Human   188 ISDYAQTLSKTPGLPSFRALAFRHG-LGPVDTAWSAVRIGLYAQHLDHWLRYFPLSHFLFVSGER 251

  Fly   294 LIMDPAYEIGRVQDFLGLKRVVTEKHFYFNATKGFPCLFKSEARSTPHCLGKTKGRNHPHIDPGA 358
            |:.|||.|:||||||||||||||:||||||||||||||.|::..|.|.||||:|||.||.:....
Human   252 LVSDPAGEVGRVQDFLGLKRVVTDKHFYFNATKGFPCLKKAQGGSRPRCLGKSKGRPHPRVPQAL 316

  Fly   359 IERLREFYRPFNNKFYQLTGINFAW 383
            :.||:|||||||.:|||:||.:|.|
Human   317 VRRLQEFYRPFNRRFYQMTGQDFGW 341

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.