DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hs3st-B and AgaP_AGAP006169

DIOPT Version :9

Sequence 1:	NP_001259702.1	Gene:	Hs3st-B / 32918	FlyBaseID:	FBgn0031005	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	XP_316229.4	Gene:	AgaP_AGAP006169 / 1276837	VectorBaseID:	AGAP006169	Length:	398	Species:	Anopheles gambiae

Alignment Length:	430	Identity:	157/430 - (36%)
Similarity:	223/430 - (51%)	Gaps:	102/430 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 SIWCSSLSL------SSRSLAIALVICVTLVYFSYSFNACLLASISRS---LQQSNLRNLLALTS 72
            :||....::      ||.|..: ||:.|:....:..|.:.:|.|:..:   |..|.:.::.|.|:
Mosquito     7 TIWLPKAAMRPFGPDSSHSDCV-LVVGVSRPKLAALFLSVMLLSLFLTFHILYDSAVYSIQAATA 70

  Fly    73 SPRNE----TNNAANSSSSNSSSSRNSSSTTGAPPAQTVTSSLDGAPKYQLLRQQGLRPSR-HLP 132
            ...|:    ||:..|                  ||               ::.|..:.|:| |.|
Mosquito    71 ISENKISILTNHIPN------------------PP---------------VINQPVVFPNRIHFP 102

  Fly   133 DT---------------------------------------------LIIGVKKSGTRALLEFIR 152
            .|                                             |||||:|.|||||||.:.
Mosquito   103 KTSRRLPQVSRLEPSFLCLFIFISLPNNPSLLALLFFPFFLAFVSQCLIIGVRKCGTRALLEMLY 167

  Fly   153 LHPDVRAAGSEVHFFDR--HYQRGLRWYRHHMPYTIEGQITMEKTPSYFVTKEVPQRVYHMNPAT 215
            |||.::.|..|||||||  :|.|||.|||..||::..||||:||:||||||.|||:||..||.:.
Mosquito   168 LHPRIQKAAGEVHFFDRDENYLRGLEWYRKKMPHSFRGQITIEKSPSYFVTPEVPERVRAMNASI 232

  Fly   216 KLLIVVRDPVTRAISDYTQAASKKADMKLFEQLAFV-NGSYSVVDTNWGPVKIGVYARYLERWLL 279
            |||::||:|||||||||||.....|..:.||:||.: ||:   |:..:.|:.|..|..::.|||.
Mosquito   233 KLLLIVREPVTRAISDYTQLRMYGAVDRSFEELALLPNGT---VNEAYRPLAISQYHVHVHRWLE 294

  Fly   280 YFPLSQLLFISGERLIMDPAYEIGRVQDFLGLKRVVTEKHFYFNATKGFPCLFKSEARSTPHCLG 344
            .||..|||.::|::||.||..::.|::||||::..:...:||||.||||.|| ::|  :...||.
Mosquito   295 VFPREQLLVVNGDQLIDDPVSQLRRIEDFLGIEPRIGSNNFYFNETKGFYCL-RNE--TGDKCLR 356

  Fly   345 KTKGRNHPHIDPGAIERLREFYRPFNNKFYQLTGINFAWP 384
            :||||.||.:||..|.:||:|:...|.|||:|.|.:..||
Mosquito   357 ETKGRKHPRVDPVVISKLRKFFVEHNQKFYELVGEDLGWP 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hs3st-B	NP_001259702.1	Sulfotransfer_1	131..368	CDD:279075	124/284 (44%)
AgaP_AGAP006169	XP_316229.4	Sulfotransfer_1	150..381	CDD:279075	122/236 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D712400at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820