DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hs3st-B and ndst1a

DIOPT Version :9

Sequence 1:	NP_001259702.1	Gene:	Hs3st-B / 32918	FlyBaseID:	FBgn0031005	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_001311428.1	Gene:	ndst1a / 100329944	ZFINID:	ZDB-GENE-111012-2	Length:	869	Species:	Danio rerio

Alignment Length:	324	Identity:	95/324 - (29%)
Similarity:	145/324 - (44%)	Gaps:	72/324 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 PPAQTVTSSLDGAPKY--------QLLRQQGLRPSRH------------LPDTLIIGVKKSGTRA 146
            ||.|.       |.||        :.|.|......||            .|..|:||.:|:||.|
Zfish   549 PPLQL-------AEKYFHMFPSDTEPLWQDPCEDKRHKDIWSKEKTCDRFPKLLLIGPQKTGTTA 606

  Fly   147 LLEFIRLHPDV------RAAGSEVHFFDRH-YQRGLRWYRHH--MPYTIEGQITMEKTPSYFVTK 202
            |..|:.:|||:      :....|:.||..: ||||:.||..:  :|.....:...||:.:||.:.
Zfish   607 LYLFLGMHPDLTSNYPSKETFEEIQFFSGYNYQRGIDWYMEYFPLPSNSSSEYYFEKSANYFDSD 671

  Fly   203 EVPQRVYHMNPATKLLIVVRDPVTRAISDYTQAASKKADMKLFEQLAFVNG-----SYSVVD--- 259
            ....|...:.|..|::.|:.|||.||.:.|              |...|:|     .||..|
Zfish   672 VAALRAAALLPRAKIITVLSDPVDRAYAWY--------------QHQRVHGDPVALKYSFHDVIT 722

  Fly   260 -TNWGPVKI----------GVYARYLERWLLYFPLSQLLFISGERLIMDPAYEIGRVQDFLGLK- 312
             ::..||::          |.|:::|.||:.:|..||:|.:.|:.|..|||..:.::|.||||:
Zfish   723 ASHNAPVRLQTLQKRCLLPGFYSKHLTRWIQHFHHSQILVVDGQTLKTDPASVLEKIQTFLGLEN 787

  Fly   313 RVVTEKHFYFNATKGFPCLFKSEARSTPHCLGKTKGRNHPHIDPGAIERLREFYRPFNNKFYQL 376
            ||...|...||..|||.|......::  .|||::||:.:|.:|..:...||.:|...|.:..:|
Zfish   788 RVDYHKILAFNPKKGFWCQLLDGGKT--KCLGRSKGQRYPDMDTQSQVFLRNYYSDGNIELSKL 849

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hs3st-B	NP_001259702.1	Sulfotransfer_1	131..368	CDD:279075	83/265 (31%)
ndst1a	NP_001311428.1	HSNSD	27..502	CDD:288882
ndst1a	NP_001311428.1	Sulfotransfer_1	592..839	CDD:279075	82/262 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810