DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ulp1 and senp3b

DIOPT Version :9

Sequence 1:	NP_573362.1	Gene:	Ulp1 / 32910	FlyBaseID:	FBgn0027603	Length:	1513	Species:	Drosophila melanogaster
Sequence 2:	NP_001077311.1	Gene:	senp3b / 565123	ZFINID:	ZDB-GENE-030131-6714	Length:	515	Species:	Danio rerio

Alignment Length:	560	Identity:	127/560 - (22%)
Similarity:	212/560 - (37%)	Gaps:	143/560 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly  1048 VGSRYLKPGTPPTFQRAKAQSATSSSCSLQDNQSNI-TDSFPSPHGRANPELTEYAKLINRQENE 1111
            :|...:.|.:||        :|||.......|:..: ::.:..|     .||.|.|..   .|||
Zfish     1 MGGGLMDPNSPP--------NATSPIHLKLSNRERVWSEDYIEP-----VELDEEAGF---DENE 49

  Fly  1112 ENRSPAPQQPKRNASNSSASHASTISSSASSSCSTCSTCSSSDTEPMLVKDSPEVKEAN------ 1170
            ::.....::.:....          .....|.|:........:...|..:..|.|..||
Zfish    50 DDMEEDEEEDEEERD----------EEDIDSECAPWEEKDDLEDWQMPFESQPHVMLANTYQQQV 104

  Fly  1171 EANEANEANEANETKENDAPQPTTTRIKKPDFLH----------RRFANCIFLRNDFAENFKA-- 1223
            ...|....::|.:..||    |...|      ||          ||..:...|||...:|:|.
Zfish   105 TLTEGEAKSQARDFSEN----PFQMR------LHGLRQQRLNRWRRLRSSARLRNRLVQNWKTWR 159

  Fly  1224 ------------RANRRQLESMH---------------LLGIAEQQANESKDERLAYE------- 1254
                        ||.|.:..|::               |.|:......|::::..||.
Zfish   160 QQAQWVGTLGYRRARRWRQYSLYASKKREKGCDTKGSTLRGLVTTSERETENQFSAYNGYGDSQS 224

  Fly  1255 ----KKLREVMFRSGAPHRPFFE-------------IGPLEQPEEKKETKLIPLTKEDHAR---- 1298
                ..:||.:   ..|.:|..:             :..|.:.:.:|...|||:..:|.|.
Zfish   225 VSSLSGVREYL---SMPMKPTIQRIEMTLTEEHKAYVHGLIEDDLRKYGSLIPVHADDIAEQLQS 286

  Fly  1299 -----FQEMTTIEVTTNLI--------------FKYNLQ---ITTDDIFTFVDGEWLNDAIINFY 1341
                 |.:........:||              |:.|.:   :|.||:.|.....||||.::|.|
Zfish   287 IFNEDFSQTHRKMAVQHLIQSYQRSSGTAMVKGFRVNYKRHVLTMDDLSTLYGQNWLNDQVMNMY 351

  Fly  1342 MSMLTERSEKRAGELPATYAMNTFFMPRLLQAGYAGVRRWTRKVDLFSKDIIPVPVHCGNVHWCM 1406
            ..::.:...::      .:..|:||..:|...||.||:|||:.||:|.||::.:|:|. .|||.:
Zfish   352 GDLVMDSVPEK------VHFFNSFFYDKLRTKGYDGVKRWTKNVDIFQKDLLLIPIHL-EVHWSL 409

  Fly  1407 AIIHLRNKTIFYYDSMGRPNQPALDALVKYLHEESLDKRKQPFDMTGFVVENAQNIPRQGNSSDC 1471
            ..:.::.::|.|:||....|:.....:.|||..|::.|.|:.| :||:......|:.||.|.|||
Zfish   410 VSVDIKRRSITYFDSQRTLNRRCPKHIFKYLQAEAMIKEKRDF-LTGWKGFFKMNVGRQNNDSDC 473

  Fly  1472 GVFSCMFAEYITRDVPITFSQAEMLYFRTKMALEIADGKL 1511
            |.|...:.:.:....|.:|||.:|...|..|..|:...||
Zfish   474 GAFVLQYCKCLALGQPFSFSQQDMPKLRRMMYKELCHCKL 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ulp1	NP_573362.1	Ehrlichia_rpt	200..>580	CDD:118064
Ulp1	NP_573362.1	Peptidase_C48	1331..1506	CDD:280975	57/174 (33%)
senp3b	NP_001077311.1	Peptidase_C48	341..513	CDD:280975	58/179 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579504
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5160
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1480705at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12606
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.850