Protein Alignment Ulp1 and Senp1

DIOPT Version :10

• Sequence 1: NP_573362.1
• Gene: Ulp1 / 32910
• FlyBaseID: FBgn0027603
• Length: 1513
• Species: Drosophila melanogaster
• Sequence 2: XP_006520943.1
• Gene: Senp1 / 223870
• MGIID: 2445054
• Length: 698
• Species: Mus musculus
• Alignment Length: 762
• Identity: 212/762 - (27%)
• Similarity: 316/762 - (41%)
• Gaps: 202/762 - (26%)

  Fly   859 RESETDSTDTGTGFQA------QNGKGFGAGRQPENSFLSQKRRNQEENPRLIKYRRVDNSFPRL 917
            :..|.|.|..|....|      .:|..|...|.|::.|..::....::.....:...:|.||
Mouse    29 KRPEMDDTADGVKMDAGEVTLVNHGSTFRTHRPPQSGFPEEQLLLSDQQSLPFRQGTLDGSF--- 90

  Fly   918 ITNETAEDLIPNNSMAKR-----DQPQSSKRLSIFNPPVYTQH---RVRNDAPHVPTPFDDEESS 974
             |..|       .|.|.|     |.|.|...|...:...:.|.   :.||..|
Mouse    91 -TCST-------RSPAYRPDYHSDNPSSDSFLGSGDVRTFGQSANGQWRNSTP------------ 135

  Fly   975 QRLANAGPSSRPMTYSD---AVRLGHNGISESRVNGHSSH-----------TVRREPS-----RL 1020
               |:.....:|.....   ..|...:|:|.:.| |.|:|           .::..||     ..
Mouse   136 ---ASGSAPQKPRNSRSLCLETRKTSSGLSNTFV-GKSNHHCHMSAYEKSFPIKPAPSPSWSGSC 196

  Fly  1021 HRSILS-------HEMNCKD--QEQYNELIRTQTNYVGSRYLKPGTPPTFQRAKAQSATSSSCSL 1076
            .||:||       |....::  ||:..|:.|.....|..:......|.|....:.     |.| |
Mouse   197 RRSLLSPKKTQRRHFSTAEETVQEEEKEIYRQLLQMVTGKQFCVAKPTTHFPLRL-----SRC-L 255

  Fly  1077 QDNQSNITDSFPSPHGRANPELTEYAKLINRQENEENRSPAPQQPKRNASNSSASH--ASTISSS 1139
            ..|::::.||.                                  .|| .||.|||  .|..|||
Mouse   256 SSNKNSLKDSL----------------------------------LRN-GNSCASHVIGSDTSSS 285

  Fly  1140 ASSSCSTCS-----------------TCSSSDTEPMLVKDSPEVKEANEANEANEANEANET--- 1184
            .|:|..|..                 ...|.|::|.....:|.  :.|....:|..:|.:::
Mouse   286 GSASILTAQEQLSHSAHSLSSGTPDVAFGSKDSDPHHHLAAPH--QPNSLPASNTQSEGSDSVIL 348

  Fly  1185 ---KENDAPQPTTTRIKKPDFLHRR-------FANCIFLRNDFAENFKARANRRQLESMH----- 1234
               ||:..|   .:|...|  |.||       ::..:.|.:.....|:|....::|.|::
Mouse   349 LKVKESQTP---ASRYLSP--LKRRSCPYIIPYSAVMDLLSSSPTFFQAELWIKELTSVYDSRAR 408

  Fly  1235 --LLGIAEQQ--ANESKDERLAYEKKLREVMFRSGAPHRPFFEIGPLEQPEEKKETKLIPLT--- 1292
              |..|.||:  |.:.:::||   ::....:..|...|        |..|.||:    ||:|
Mouse   409 ERLRRIEEQKALALQLQNQRL---QEQEHAVLDSVELH--------LRVPLEKE----IPVTAAQ 458

  Fly  1293 ---KEDHA------RFQEMT-TIEVTTNLIFK-----------YNLQITTDDIFTFVDGEWLNDA 1336
               |:.|.      .|.|:| .:|.....:|:           :.|.||..||.|.....||||.
Mouse   459 ETRKKSHQLTDSEDEFPEITEEMEKEIKNVFRNGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDE 523

  Fly  1337 IINFYMSMLTERSEKRAGELPATYAMNTFFMPRLLQAGYAGVRRWTRKVDLFSKDIIPVPVHCGN 1401
            ||||||:||.|||:::.  .|:.:|.||||..:|..|||..|:|||:|||:||.||:.||:|.|
Mouse   524 IINFYMNMLMERSKEKG--FPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFSVDILLVPIHLG- 585

  Fly  1402 VHWCMAIIHLRNKTIFYYDSMGRPNQPALDALVKYLHEESLDKRKQPFDMTGFVV--ENAQNIPR 1464
            ||||:|::..|.|:|.||||||..|..|...|::||.:||:||:::.||..|:.:  :.:|.||:
Mouse   586 VHWCLAVVDFRRKSITYYDSMGGINNEACRILLQYLKQESVDKKRKEFDTNGWQLFSKKSQEIPQ 650

  Fly  1465 QGNSSDCGVFSCMFAEYITRDVPITFSQAEMLYFRTKMALEIADGKL 1511
            |.|.||||:|:|.:|:.||:|.||.|:|..|.|||.:|..||...||
Mouse   651 QMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKL 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ulp1	NP_573362.1	sbcc	<294..>551	CDD:129705
		Peptidase_C48	1331..1506	CDD:397169	90/176 (51%)
Senp1	XP_006520943.1	mukB	<407..>501	CDD:235316	23/108 (21%)
		Peptidase_C48	<474..696	CDD:420019	103/224 (46%)