DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ulp1 and Senp6

DIOPT Version :10

Sequence 1:NP_573362.1 Gene:Ulp1 / 32910 FlyBaseID:FBgn0027603 Length:1513 Species:Drosophila melanogaster
Sequence 2:NP_001298039.1 Gene:Senp6 / 215351 MGIID:1922075 Length:1139 Species:Mus musculus


Alignment Length:960 Identity:184/960 - (19%)
Similarity:333/960 - (34%) Gaps:306/960 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   576 DQEEDQHYLNFEGNQQFQLQKQDQ----------LSVPQIQKQTHQFESKVKK-RKLQPFSEYQQ 629
            |:.|.:....|:.|..|..:::.:          |||       ...:|::.| :||...||...
Mouse    19 DRSESKRDGGFKNNWSFDHEEESEGDADKDGANLLSV-------EDEDSEISKGKKLNRRSEIVA 76

  Fly   630 KGQKDHIQERQYIQQEFT---------------IHSNQAYSKVQYIQTIQTA-----TPYVPQLE 674
            ....|.|. :.|:::..|               :.:|:..|:    .|..||     ..:..:..
Mouse    77 TSSGDFIL-KTYVRRSKTDGFKTLKGNPIGLNMLSNNKKLSE----STAGTALCSGTVVHGRRFH 136

  Fly   675 ISQENSFEVQPAYEVNEGQRDRELVSYTGHEHQNFVDEVSTPLPPAEAQPGSTSEDISDPVSPEH 739
            .:...:..::.|.:.|:.:::|:  .|..:.|:            ||          :.||...|
Mouse   137 HAHSQTPGIRTAAQSNQDRKERK--EYPPYVHK------------AE----------NSPVMLSH 177

  Fly   740 WEQLESLDPSTICIRKTFNLIRDISESLVADPEQPEAEAHRKSIFLLRQK----------LADVC 794
            .:..:.:      ::||     :.|||.|      |:|..||    ::||          |:...
Mouse   178 GQGGDHI------MKKT-----EESESYV------ESEIKRK----VQQKRHCSTYQLSPLSPAS 221

  Fly   795 HKVLTEIIHGRATDEIISILREILEQTKEIPPRPTPKRDLQEDISMGLEILKKIRGMLSGWYSSR 859
            .|.||.:              |:.||.:..|.....|.:..:..|.|:.....::      .:.|
Mouse   222 KKCLTHL--------------EVSEQREYCPKCGKEKENQTKCQSCGIVFHNDLQ------RNCR 266

  Fly   860 ESETDSTDTG----TGFQAQNGKGFGAGRQPENSFLSQKR---RNQEENPRLIKYRRVDNSFPRL 917
            ::.|.:..||    |.....:|     |::.:|:.|:.|:   .:.::.|..|.....|:....:
Mouse   267 QAVTLNEPTGPLLRTSIHQNSG-----GQKSQNTGLTAKKFYGNSVDKIPIDILVTCDDSRHNYI 326

  Fly   918 ITNETAEDLIPNNSMAKRDQPQSSK-RLSIFNPPVYTQHRVRNDAPHVPTPFDDEESSQRLANAG 981
            .||  .:.::|...:.|...|:..| .:|..|.|:.           :.:..||::..:......
Mouse   327 QTN--GKVILPGGKIPKLTNPKERKISVSDLNDPII-----------LSSDDDDDDDDRTKRRES 378

  Fly   982 PSSRPMTYSDAVRLGHNGISESRVNGHSSHTVRREP------SRLHRSILSHEMNCKDQEQYNEL 1040
            .|.:|...:.:..:...|..|:.:|..:.. ..:||      ..|:..::..:...|||      
Mouse   379 TSPKPADSACSSPVPSTGKVEAALNADACR-AEQEPRSSPAEPELNTIVIPRKARMKDQ------ 436

  Fly  1041 IRTQTNYVGSRYLKPGTPPTFQRAKAQSATS----SSCSLQDNQSNITDSFPSPHGRANPELTEY 1101
                   :|:....|     .:|.|..|..:    .|.|.|:.:|.|.:.      |:....|.:
Mouse   437 -------LGNSISTP-----LKRRKVNSHAAFIHPMSLSCQNFESVILNC------RSIRVGTLF 483

  Fly  1102 AKLINRQENEENRSPAPQQPKRNASNSSASHASTISSSA------SSSCSTCSTCSSSDTEPMLV 1160
            ..|:              :|...:..|...|.....|..      :|..:.|..|:......:.:
Mouse   484 RLLV--------------EPVIFSLESITIHLDGPESDPVDIILNTSDLTKCEWCNVRKLPVVFL 534

  Fly  1161 KDSPEV-----------KEANEANEANEANEANETKEN----------DAPQPTT---------T 1195
            :..|.|           ||....|:....|.....:|.          |......         .
Mouse   535 QAIPAVYQKLSMQLQMSKEDKVWNDCKGINRITSLEEQYIILIFQTGLDHQAEVVFESIITDIGI 599

  Fly  1196 RIKKPDFLHRRFANCIFLRNDFAENFKARANRRQLESMHLLGIAEQQANESKDERLAYEKKL--- 1257
            |...|:|    ||..:|   |.|.:......|...||  :.|...|:  |:|.:.:::|.|:   
Mouse   600 RNNVPNF----FAKILF---DEANSRLVACTRSYEES--IKGNCAQK--ENKVKTVSFESKIQLR 653

  Fly  1258 --REVMF-----RSGAPHRPFFEIGPLEQPEEKKETKLI-----PLTKEDHARFQEMTTIEVTTN 1310
              :|:.|     .:|..|..|  |||:|        |||     |.                   
Mouse   654 SKQELQFFDDDEEAGESHTIF--IGPVE--------KLIVYPPPPA------------------- 689

  Fly  1311 LIFKYNLQITTDDIFTFVDGEWLNDAIINFYMSMLT-ERSEKRAGELPATYAMNTFFMPRL---- 1370
               |..:.:|.:|:....:||:|||.||:||:..|. |:.:|.  :....:..::||..||    
Mouse   690 ---KGGISVTNEDLHCLSEGEFLNDVIIDFYLKYLVLEKLKKE--DADRIHIFSSFFYKRLNQRE 749

  Fly  1371 -----------LQAGYAGVRRWTRKVDLFSKDIIPVPVHCGNVHWCMAII 1409
                       .|..:..|:.|||.||:|.||.|.||:: ...||.:|::
Mouse   750 RRNPETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLN-EAAHWFLAVV 798

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ulp1NP_573362.1 sbcc <294..>551 CDD:129705
Peptidase_C48 1331..1506 CDD:397169 31/95 (33%)
Senp6NP_001298039.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 23..51 3/27 (11%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 334..395 11/71 (15%)
Protease 693..1139 34/109 (31%)
Peptidase_C48 707..>819 CDD:420019 31/95 (33%)
Peptidase_C48 <999..1075 CDD:420019
Blue background indicates that the domain is not in the aligned region.

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