DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ulp1 and senp7b

DIOPT Version :9

Sequence 1:	NP_573362.1	Gene:	Ulp1 / 32910	FlyBaseID:	FBgn0027603	Length:	1513	Species:	Drosophila melanogaster
Sequence 2:	XP_005161832.1	Gene:	senp7b / 100006377	ZFINID:	ZDB-GENE-060531-45	Length:	884	Species:	Danio rerio

Alignment Length:	869	Identity:	167/869 - (19%)
Similarity:	283/869 - (32%)	Gaps:	313/869 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   884 RQPENS----FLSQKRRNQEENPRLIKYRRVDNSFPRLITNETAEDLIPNNSMAKRDQPQSSKR- 943
            :||.:|    ..|...|.|::|.:..::..|  :|.....::|:.:   .|.::|..|...|.|
Zfish    30 KQPSDSCSLDMQSPLSRLQDDNSQKSQWGSV--TFNGRTPHKTSSN---ENMLSKDSQRSDSLRG 89

  Fly   944 -------LSIFNPPVYTQHRVRNDAPH-------------VPTPFDDEESSQRLANAGPSSRPMT 988
                   ..:...|:.......|..||             .||...|..::.|.       ||..
Zfish    90 ATRGRFSFKMNQQPIKISPARVNGTPHKVSDTSGFRPQCQTPTTAPDFTANNRW-------RPKR 147

  Fly   989 YSDAVRLGHNGISESRVNGHSSHTVRREPS--RLHRSILSHEMNCKDQE---QYNELIRTQTNYV 1048
            .||.: |.|:          .:||...|.|  ::||.:.|.|:..::.|   .::::..||....
Zfish   148 ASDRL-LSHD----------ENHTKASECSAFKIHRGLDSEELEEEETEGTQGHSQVKETQRATS 201

  Fly  1049 GSRYLKPGTPPTFQRA--KAQSATSSSCSLQDNQSNI-TDSFPSPHGRANPELTEYAKLINR--- 1107
            ...|........|::|  |.::.|..:.|...|.|.: ....|:.|.|.:.|....:..:.:
Zfish   202 SEDYKVTSAASVFEKATSKHKNGTEKAVSKPFNHSGLHVQEAPARHLRTSEERAASSVPVRKDPL 266

  Fly  1108 -QENEENRSPAPQQPKRNASNSSASHASTISSSASSSCSTCSTCSSSDTEPMLVKDSPEVKEANE 1171
             .|..||:|..|         .::.::|.:.....|.|.|......|.|||:::....|  .|||
Zfish   267 TSETAENKSKDP---------FASFYSSKLRRKPQSFCKTYKRTKPSSTEPIVLSSDDE--GANE 320

  Fly  1172 ANEAN---------------EANEANETKENDAPQPTTTRIKKPDFLHRRFANCIFLRNDFAENF 1221
            .|:.:               :......:|.|...:.:||:::.|..:...|:...:      :..
Zfish   321 VNDVSGGLQEQRISEGIRDTQTGNQKSSKTNVGGERSTTKVEVPSIMELEFSRLHY------DTI 379

  Fly  1222 KARAN------------------------------RRQLESM---------HLLGIAEQQA---- 1243
            :|:||                              :.|:..|         .||.|.|:.|
Zfish   380 QAQANGTVVITDEGISIPLKDADGEGEVAISISCSQLQMYGMWDGGLASDGSLLSITEEPAPSLF 444

  Fly  1244 -------------------------------------NESKDERLAYEKKLREVM---------- 1261
                                                 .:..|.|:|....|.:|:
Zfish   445 FLMVSDAQARLLRKELSLQYNTHTSGQACPFVLLVLSGQLDDLRVALLASLMDVIGLRYAQDSLS 509

  Fly  1262 ----FRSGA------PHRPFF---------EIGPLEQPEE----KKETKLIPLTKEDHARFQEMT 1303
                :..|.      |....|         :.|..:..|.    |:.|...||  ..|::.|.:
Zfish   510 NPVSWADGLSRLLCHPRGEHFLSLLGQNCKDTGQDKAKENASGIKEPTARRPL--RSHSKPQSL- 571

  Fly  1304 TIEVTTNLI------FKYNLQITTDDIFTFVDGEWLNDAIINFYMS-MLTERSEKRAGELPATYA 1361
                ...||      .|..:.:||:|:....|||:|||.||:||:. :|.||::|...|  .::.
Zfish   572 ----PRRLIQYPPPPSKGGITVTTEDLECLKDGEFLNDVIIDFYLKYLLLERADKDIAE--RSHI 630

  Fly  1362 MNTFFMPRLLQAGYAG---------------VRRWTRKVDLFSKDIIPVPVHCGNVHWCMA---- 1407
            .::||..:|.:...:|               ||.|||.||:||||.:.:||: ...||.:.
Zfish   631 FSSFFYKQLTRKDTSGPEETGSTSAYRRHQRVRTWTRHVDIFSKDYLFIPVN-HEAHWYLVLICF 694

  Fly  1408 -------IIHLRNKTIFYYDS--------------------MGRP---------NQPALDALVKY 1436
                   |:..|.|:....|.                    .|.|         |.|  |..|..
Zfish   695 PALERPQIVEWRQKSSVSQDESQTTKERPSGESQRESSQQPKGNPSKINESRSHNLP--DCTVHS 757

  Fly  1437 LHEESLDKRKQPFDMTGFVVENAQ----------------------------------NIPRQGN 1467
            ..:|::.||.....|....:...|                                  .:|.|.|
Zfish   758 CTKETICKRPCILIMDSLKLSYHQRTYTLLREYLQVEWEVRKGSCRSFSNESITGSLCRVPLQDN 822

  Fly  1468 SSDCGVFSCMFAEYITRDVPITFS 1491
            |||||::...:.|...::..:.|:
Zfish   823 SSDCGLYLLQYVESFLQNPVVDFA 846

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ulp1	NP_573362.1	Ehrlichia_rpt	200..>580	CDD:118064
Ulp1	NP_573362.1	Peptidase_C48	1331..1506	CDD:280975	57/251 (23%)
senp7b	XP_005161832.1	Peptidase_C48	601..845	CDD:304959	56/248 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5160
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810