DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7556 and dnajc1

DIOPT Version :9

Sequence 1:	NP_001285427.1	Gene:	CG7556 / 32902	FlyBaseID:	FBgn0030990	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_001011351.1	Gene:	dnajc1 / 496816	XenbaseID:	XB-GENE-950431	Length:	535	Species:	Xenopus tropicalis

Alignment Length:	547	Identity:	182/547 - (33%)
Similarity:	277/547 - (50%)	Gaps:	118/547 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LAGLLLLCAT---GASAWHSEELEIFDLVEEVNRNFYEFMGINQTATGAEVKRAFRTLSIVLHPD 70
            |..:||||.|   ...||.|.:||:||||||:.:|||||:|:.|.|:.|::::|:|.||:.||||
Frog     9 LLSVLLLCCTQPHNVGAWDSGDLELFDLVEEIQQNFYEFLGVEQDASSADIRKAYRKLSLTLHPD 73

  Fly    71 KNPAEDANIQFRNLVSIYEVLKDPSRREKYDRVLKEGMPNWKSALYYYRRMRKIGLYEGAFILFL 135
            ||..|:|..|||.||:|||||||..||::||.:|..|:|:|:..::||||:||:...|.|.:||:
Frog    74 KNKEENAETQFRQLVAIYEVLKDEERRQRYDDILVNGLPDWRQPVFYYRRVRKMSNAELALLLFI 138

  Fly   136 ITTVGQYLFAWAAYLEKKYTAEQVFGTKLKKLQK----------KNKNIDMDVILSEIPMPSLLN 190
            |.|||.|..||:.||||:  .:::...|.|:.:|          |:..|:.:..:||  .|...:
Frog   139 IFTVGHYAVAWSIYLEKQ--LDELLSKKKKEKKKKAGAKTLDEIKSGQIEKNERVSE--KPQWRD 199

  Fly   191 TLPIQIPLALW------NLPRTIKNGFSKANELKELALEKRRQELEAVRRQEELEREAEEQARLR 249
            .||.:  |.:|      :||:..::......|.:|..| |.::|.||:...|.:::|.:.:.:..
Frog   200 LLPFK--LGIWFYLTVRSLPQLYQDAKQYYAEYQEKKL-KEKEEAEALAELELIQKEKKPKVKKP 261

  Fly   250 KEHKENLRKRKQNSKAPEKTEEELRGYSQ---IQTRELTDDDAV--RPASQKSTVSGGFWTDEDL 309
            |...........|..||        .|.|   |:..|...||.:  |..:||.....  ||:|||
Frog   262 KSEFPVYSASTANITAP--------AYDQSASIEDIEEQMDDWLDCRGRNQKKKAPE--WTEEDL 316

  Fly   310 TELIRLVKKYPGGAGSRWNTIAESMNRSVQEVTFMAAKMKE-----------NGYRIPGQTD-SV 362
            ::|.|.:.|:|||...||..||..:.|||.:||..|.::|:           :..:...:.. |:
Frog   317 SQLTRSMAKFPGGTPGRWEKIAHELGRSVADVTTKAKQVKDAVSCSLGTVRFSDLKCSAKASVSL 381

  Fly   363 AEALV------QESQQAQ------------------RKEKVKKAAANA-----GASAEK------ 392
            :::::      :|.|.::                  ||.|..|.|.:|     |.:.||
Frog   382 SDSIITHREEEEEEQDSEEQDLSASQGEGHSTAARVRKRKSTKGATDAVPPLRGEAEEKVRSRRQ 446

  Fly   393 --------------------------SMLIPETNWTQEQQRALEAAIVKYRKTAGGDRWQKIANS 431
                                      |:   |..|||.||:.||.|:.:|.| ..|:||.|||..
Frog   447 RDFDVEQEAEELADSDSDTRKKEQGRSL---EELWTQNQQKLLELALQQYPK-GTGERWDKIAKC 507

  Fly   432 VPEKTKEECLVRYKYLCELVKTQKRAE 458
            ||.|:||:|:.|||.|.|||:.:|:|:
Frog   508 VPGKSKEDCICRYKLLVELVQKKKQAK 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7556	NP_001285427.1	DnaJ	40..101	CDD:278647	35/60 (58%)
		SANT	301..>341	CDD:197842	18/39 (46%)
		SANT	304..341	CDD:238096	18/36 (50%)
		SANT	399..447	CDD:197842	25/47 (53%)
		SANT	400..447	CDD:238096	25/46 (54%)
dnajc1	NP_001011351.1	DnaJ	43..104	CDD:365959	35/60 (58%)
		SANT	310..356	CDD:238096	21/47 (45%)
		SANT	478..524	CDD:238096	25/46 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	87	1.000	Domainoid score	I7916
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	249	1.000	Inparanoid score	I3167
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D412930at33208
OrthoFinder	1	1.000	-	-		FOG0005801
OrthoInspector	1	1.000	-	-		oto102830
Panther	1	1.100	-	-	LDO	PTHR44653
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1934
SonicParanoid	1	1.000	-	-		X5521
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.190