Protein Alignment: HSD11B1 and CG31937

• Sequence 1: NP_001193670.1
• Gene: HSD11B1
• HGNCID: 5208
• Length: 292
• Species: Homo sapiens
• Sequence 2: NP_608616.2
• Gene: CG31937
• FlyBaseID: FBgn0031360
• Length: 321
• Species: Drosophila melanogaster
• Alignment Length: 267
• Identity: 71/268 (26%)
• Similarity: 116/268 (43%)
• Gaps: 60/268 (22%)

Human     1 MAFMKKYLLPILGLFMAYY-------------YYSANEEFRPEMLQGKKVIVTGASKGIGREMAY 52
            |:|: ::||.:|.|:...|             :|.:........::|:.|.:||||.||||.:|.
  Fly     1 MSFL-EFLLLLLVLYYVVYVLLWILLDCNVALWYKSRFGVSLSSMRGQVVWITGASSGIGRALAL 64

Human    53 HLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLI 117
            .||:.|..:|::||..|.|::|...||    |:|..:..|.:.:...             :|||.
  Fly    65 SLARHGVKLVLSARRLEQLEQVQEECL----AAARGLLATKDVLVIQ-------------MDMLD 112

Human   118 LN-HIT--NTSLNLFHD-------------------DIHHVRKSMEVNFLSYVVLTVAALPMLKQ 160
            |: |.|  ||.||.||.                   :|...|:..|::..:.|.|:...:....:
  Fly   113 LDEHKTHLNTVLNHFHRLDVLVNNAGRSQRASWTEVEIEVDRELFELDVFAVVHLSRLVVRYFVE 177

Human   161 SNGS---IVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTET 222
            .||.   |...||:||....|....|.|:|.||:.:..|::.|..    .:.::|...|.|.|:.
  Fly   178 QNGGRGHIAATSSIAGFSPVPFSPTYCAAKHALNAYLLSLKVEMR----KLDVSLFAPGPIATDF 238

Human   223 AMKAVSG 229
            ..:|.:|
  Fly   239 LQEAFTG 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSD11B1	NP_001193670.1	11beta-HSD1_like_SDR_c	32..279	CDD:187593	63/224 (28%)
CG31937	NP_608616.2	NADB_Rossmann	44..293	CDD:304358	63/224 (28%)
		adh_short	47..245	CDD:278532	61/219 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E2759_KOG1205
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D906746at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910