Protein Alignment htk and SWI1

DIOPT Version :10

• Sequence 1: NP_573330.3
• Gene: htk / 32877
• FlyBaseID: FBgn0085451
• Length: 2486
• Species: Drosophila melanogaster
• Sequence 2: NP_015309.1
• Gene: SWI1 / 856091
• SGDID: S000005937
• Length: 1314
• Species: Saccharomyces cerevisiae
• Alignment Length: 661
• Identity: 109/661 - (16%)
• Similarity: 202/661 - (30%)
• Gaps: 254/661 - (38%)

  Fly   118 FNESETLDQLPLTHPEHFGNPVVGGRRGRRRGHLNE------DSSEDDDESDAKEVVNEKEENIG 176
            ||.|.: :...||..:...|........|.....||      |::.:.:..:.:...|.|..|..
Yeast   239 FNNSAS-NNGNLTSNQLISNYAASNSMDRSSSASNEFVPNTSDNNNNSNNHNMRNNSNNKTSNNN 302

  Fly   177 KVVCVETESKKKDKEKWFPALVVAPTAQAT--------------VRIRVKDEYLVRSFKDGRYYT 227
            .|..|             ||...|.|..:|              ..::.|.:...::.:..:...
Yeast   303 NVTAV-------------PAATPANTNNSTSNANTVFSERAAMFAALQQKQQQRFQALQQQQQQQ 354

  Fly   228 VPKKEATEFTREVASKQDVPAVQAALEFLDS-----------SVLPAHWDRDSLFGLTNISSDDE 281
            ..:::..:..::...:|..|      :||.|           |:.||
Yeast   355 QNQQQQNQQPQQQQQQQQNP------KFLQSQRQQQQRSILQSLNPA------------------ 395

  Fly   282 GEIDSDSSDDEPHEEKDRFVAQLYKYMDDRGTPLNKVPSILSRDVDLYRLFRAVQKRGGYNRVTS 346
              :....|.:..:::.:.|:..|.:....|..||..:|.|.:|.::|:.|:..|||.||.::||.
Yeast   396 --LQEKISTELNNKQYELFMKSLIENCKKRNMPLQSIPEIGNRKINLFYLYMLVQKFGGADQVTR 458

  Fly   347 QNQWKLIAMRLGFTPCTVSVMNLVKQAYKKFLQPYGDFHRKLGCSMLMTSRNSNRSKGRSLVRAN 411
            ..||.::|.||     .:|....::..|.:.|.||              .|:....:|....:|.
Yeast   459 TQQWSMVAQRL-----QISDYQQLESIYFRILLPY--------------ERHMISQEGIKETQAK 504

  Fly   412 SVASPKPMETMKTETISKLAQPNQTNVVASTSSSAAAASVAASSTPARAVSTASQSAAEESGNTS 476
            .:.    ::....|.:.|:.|..|...:|:.:::..:||
Yeast   505 RIF----LQQFLQELLKKVQQQQQAAALANANNNINSAS-------------------------- 539

  Fly   477 ESSVVVEPPKKQRKGSAASSQQGKVKSLVEKYEEKSTAVQATSSGTVAGSGASASAAAMPTTSAA 541
                                                      |:.|.|..|||..|.|.|.|.|.
Yeast   540 ------------------------------------------SAPTPAAPGASVPATAAPGTEAG 562

  Fly   542 ASTATNLSSATSGGSATIATTAMNKDAESDLPLAKIKAAAVAAASTRHSMEKETNISSGSSASAS 606
            .                             :|:         :|:|..|:....||:..::....
Yeast   563 I-----------------------------VPV---------SANTPKSLNSNININVNNNNIGQ 589

  Fly   607 SKANSAEMQRSRDASPSVAAPPSAGASTSGAAATAQTASNKKEKHQRSKQADKEKDKDKEEKQAS 671
            .:......||.:                            ||.|.:...:..:.:|..|.:::..
Yeast   590 QQVKKPRKQRVK----------------------------KKTKKELELERKEREDFQKRQQKLL 626

  Fly   672 SGKRKKEKISVEKIDTGDFVVGIGDKLKVNY--HEKKSPSSHGSTYEAKVIEISVQRGV-PMY-- 731
            ..:::::|:.:|            .||:..|  ..||.|         ||.:.|:.|.. |:.
Yeast   627 EDQQRQQKLLLE------------TKLRQQYEIELKKLP---------KVYKRSIVRNYKPLINR 670

  Fly   732 LVHYTGWNNRY 742
            |.||.|::..|
Yeast   671 LKHYNGYDINY 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
htk	NP_573330.3	Tudor_ARID4_rpt1	10..60	CDD:410460
		Tudor_ARID4_rpt2	65..118	CDD:410461	109/661 (16%)
		RBB1NT	170..263	CDD:462390	16/117 (14%)
		ARID	296..381	CDD:460187	25/84 (30%)
		CBD_RBP1_like	698..758	CDD:350843	15/50 (30%)
SWI1	NP_015309.1	ARID_Swi1p-like	407..490	CDD:350635	27/101 (27%)
		PKK	618..>654	CDD:463600	9/56 (16%)