Protein Alignment: htk and arid4a

• Sequence 1: NP_573330.3
• Gene: htk
• FlyBaseID: FBgn0085451
• Length: 2486
• Species: Drosophila melanogaster
• Sequence 2: XP_012824464.1
• Gene: arid4a
• XenbaseID: XB-GENE-983782
• Length: 1309
• Species: Xenopus tropicalis
• Alignment Length: 1450
• Identity: 382/1450 (26%)
• Similarity: 570/1450 (39%)
• Gaps: 392/1450 (27%)

  Fly     1 MQQMDDPPSLPVGTEVSAKYKGAFCEAKVSKVVRNIKVKVAYKQGLGSGIVSDDAIKAPTGQLRV 65
            |:..|:|..|.|||:|||||:|||||||:..|.|.:||||..||...:.:|.||.:|.|   |||
 Frog     1 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVTLKQDNSTQLVQDDQVKGP---LRV 62

  Fly    66 GAVVEVRHPDRKELVEATITKIQDCSQYTVVFDDGDITTLRRTALCLKSGRHFNESETLDQLPLT 130
            ||.||::..|... .||.|:|:.|.|.|||||||||..|||||:||||..|||.|||||||||||
 Frog    63 GATVEMKTTDGSP-QEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETLDQLPLT 126

  Fly   131 HPEHFGNPVVGGR--RGRR------RGHLNEDSSEDDDESDAKEVVNEKEENIGKVVCVETESKK 187
            :|||||.||:|.:  ||||      .....|:|||::|| |.|.:   .:|.:||:|.|:. |..
 Frog   127 NPEHFGTPVIGKKTNRGRRSSLPMTEDEKEEESSEEEDE-DLKRL---NDELLGKIVSVQC-SLP 186

  Fly   188 KDKEKWFPALVVAPTAQATVRIRVKDEYLVRSFKDGRYYTVPKKEATEFTREVASKQDV--PAVQ 250
            ||   ||.||||:|:......:: ||:.|||||.|.::::|.:|:.||....|.:.:..  ..||
 Frog   187 KD---WFTALVVSPSCSDDASVK-KDQCLVRSFVDSKFHSVARKDLTEVDVNVLNSEHFGKQGVQ 247

  Fly   251 AALEFLDSSVLPAHWDRDSLFGLTNISSDDE-GEIDSDSSDD--------EPHE-----EKDRFV 301
            .|:.||.|..:|..|..|....|.:.|||:| ||.|:..||.        ||.|     |:|.|:
 Frog   248 DAIAFLISKTIPEKWKMDMNEILESSSSDEEDGEDDACDSDQNKEEEVETEPEEEADPAERDIFL 312

  Fly   302 AQLYKYMDDRGTPLNKVPSILSRDVDLYRLFRAVQKRGGYNRVTSQNQWKLIAMRLGFTPCTVSV 366
            .||||:|:|||||:||.|.:..:|::|::|||.|.::||.:.:.|...||.|.|.||......:.
 Frog   313 QQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYQQGGCDNIESGAVWKQIYMDLGIPILNSAA 377

  Fly   367 MNLVKQAYKKFLQPYGDFHRKLGCSMLMTSRNSNRSKGRSLVRANSVASPKPMETMKTETISKLA 431
            ...||.||||:|..:.::.|...........|                .|||:|..|.|
 Frog   378 SYNVKTAYKKYLYGFEEYCRSANIQFRTIHHN----------------DPKPIEEPKVE------ 420

  Fly   432 QPNQTNVVASTSSSAAAASVAASSTPARAVSTASQSAAEESGNTSESSVVVEPPKKQRKGSAASS 496
                                             .:...|.|.....:|.:::...|:...|.:||
 Frog   421 ---------------------------------EEKPMESSEQKETASPLLDAKMKEEDESDSSS 452

  Fly   497 QQGKVKSLVEKYEEKSTAVQATSSGTVAGSGASASAAAMPTTSAAASTATNLSSATSGGSATIAT 561
            :.||        ||..|.:::.     .|....|..|....|....|.....::..
 Frog   453 EYGK--------EETETEMKSP-----RGRRRCAFNAFSVVTDVEDSDTRKDNNKE--------- 495

  Fly   562 TAMNKDAESDLPLAKIKAAAVAAASTRHSMEKETNISSGSSASASSKANSAEMQRSRDASPSVAA 626
               |||.|.||               ..:.|||.:.|:....|...:|...:..:.:|.|
 Frog   496 ---NKDIEEDL---------------NKTEEKEEDESTPVRRSLQCRAKGDQKTKKQDES----- 537

  Fly   627 PPSAGASTSGAAATAQTASNKKEKHQRSKQADKEKDKDKEEKQASSGKRKKEKISVEKIDTGDFV 691
                                       .:::|::.:|..|.|:.|..|.:.|:   |..||.|..
 Frog   538 ---------------------------ERESDEDDEKPCEGKEDSEHKGETEE---EDEDTEDRD 572

  Fly   692 VGIGDKLKVNYHEKKSPSSHGSTYEAKVIEISVQRGVPMYLVHYTGWNNRYDEWVPRERIAENLT 756
            ...|.|:||.|...|:.    ..|||.:....|..|..:|||||.|||.||||||..:||.....
 Frog   573 YLAGTKVKVKYGRGKTQ----KIYEANIKSTEVDGGELLYLVHYYGWNVRYDEWVKADRIIWPSD 633

  Fly   757 KGSKQKTRTISTSSANSGSGGGGGGGGGGGGGGGGGGGSLLVQGSQPPGVSDKQPGKDGCSKMSP 821
            ||..:|.:...|.:.:.                                 ::::...|..||.
 Frog   634 KGGPKKKQKKKTKNKDE---------------------------------NEEKKEDDKRSKR-- 663

  Fly   822 SSGNSTGPGAPSLSGSLGGASSTPSLLSTVVKTPPTGGAKRGRGRSDSMPPRSTTPSSVVAHSGR 886
                    |.|.|.     ::...::...:.|||.:.|....:...:|:...|:..:.:
 Frog   664 --------GRPPLK-----SAHQTNMTCGLPKTPTSEGKTSVKNMRNSLSDSSSLSNGL------ 709

  Fly   887 TKSPAASQPQLQQQMKKRPTRVVPGTTTPRRVSDASMASESDSDSDEPVRRPKRQSAKDKPQAGK 951
                        :...:|.||...|.....|.|:.|..|||:||...     ::.|.|::....|
 Frog   710 ------------EGSARRRTRRSSGLYDSDRCSNDSSTSESESDETS-----EKASVKEEEVLPK 757

  Fly   952 AQPPGKGRLA-------------------SSASSTAPAAHPSDDSEE------------DEEEEE 985
            |:...:..|:                   ...|.|.||.....:.||            :|.||.
 Frog   758 AEEEPENILSLVDISPVKEVPPVICLLKDPEHSPTKPAETLKQEVEECEQIVQIYGKQTEELEEI 822

  Fly   986 PSAARAASSKQQQQQASSLRGSRAGGNRAMSSGAASAKGRDY---------DLSEIRSELKGFQP 1041
            ..|.....||.::   |..:.|.....:.:|:.........:         .||.::|:...|.|
 Frog   823 KEAEHLPKSKGRR---SKTKDSSVENTKCLSATQEDTLVEPHVEEDTLDLPSLSPLQSKELPFTP 884

  Fly  1042 K--LLTNAASNEERKDLAKK--EPSDEPALQDIKKEPKLESSAKSSSTELSSETESYAD---EDS 1099
            |  .|.|....:|:|.|.:|  |.|........:.:|:|........||.::|.:.:.:   ||.
 Frog   885 KEAELPNDQLAQEKKGLKRKPLEQSSPDKKLRTECDPELPVIVAEEKTEENNEAQEHFNTIHEDE 949

  Fly  1100 QSSDYRKQLKGSGAGKKEPTASPSKLHHEPVTKRELAVKEEPLKIEPKTEPKEEETKSKPFLSGA 1164
            :..:..:::         |:.: ::|.|...|:.:  ..:.||          .|..:.|:....
 Frog   950 ELPNVNEEM---------PSLT-AELEHVHSTRTD--EFDIPL----------NEITNMPYQEDQ 992

  Fly  1165 DIKPTALIAPARFGNTSAAQAASSSGSSSTTAKYTSVIVEKPLTIGGKKSVEQ-----HVPKKAE 1224
            |..||       .|..:........|......|...:::||         |||     |.|....
 Frog   993 DTMPT-------IGPENLVCHEVDLGDFDEKDKVEDIVMEK---------VEQDTQTIHPPTLPP 1041

  Fly  1225 LLKKQSGGAGGTAASSSAASQESKKFAEPVASLKVEMPA------ACSPSSS----SSSSSSFCS 1279
            .::..|.......|.|...|...|  :|...:::|:..|      .|...|:    :|::||.||
 Frog  1042 AIQPHSYSVASPLALSHDESHSIK--SESDITIEVDSVAEESQEGLCESESANGFEASTTSSNCS 1104

  Fly  1280 -----------------------------------TGSAVSSSS--------ATRSLPDMSKLEI 1301
                                               |...:|:||        .:....|:|.|:.
 Frog  1105 VTAQEADITEKGNFITCHKRINESLSGSLAKKQKRTPKRISTSSKVEKNGIGQSSDSEDLSTLDT 1169

  Fly  1302 SSGTVPGATPGAAALQPSNV 1321
            ||...|...||  .|:|..:
 Frog  1170 SSKCTPIKHPG--VLKPQKI 1187

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
htk	NP_573330.3	RBB1NT	171..262	CDD:285392	34/93 (37%)
		ARID	299..381	CDD:279697	36/82 (44%)
		Tudor-knot	692..751	CDD:288553	26/59 (44%)
arid4a	XP_012824464.1	TUDOR	58..113	CDD:197660	34/59 (58%)
		RBB1NT	171..259	CDD:285392	34/93 (37%)
		BRIGHT	308..397	CDD:128777	37/89 (42%)
		Tudor-knot	576..629	CDD:288553	27/57 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C104880024
eggNOG	1	0.900				E1_KOG2744
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0001641
OrthoInspector	0	0.000	Not matched by this tool.
Phylome	1	0.910		0.667	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	1	0.960
	5	4.700