DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment htk and Arid3c

DIOPT Version :9

Sequence 1:	NP_573330.3	Gene:	htk / 32877	FlyBaseID:	FBgn0085451	Length:	2486	Species:	Drosophila melanogaster
Sequence 2:	NP_001167452.1	Gene:	Arid3c / 502946	RGDID:	1560943	Length:	410	Species:	Rattus norvegicus

Alignment Length:	434	Identity:	98/434 - (22%)
Similarity:	151/434 - (34%)	Gaps:	111/434 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 QLPLTHPEHFGNPVVGGRRGRRRGHLNEDSSEDDDESDAKEVVNEKEENIGKVVCVETESKKKDK 190
            :|||..|     |::|.|                       .:...|..:|.|...|.|..::|:
  Rat    23 RLPLPQP-----PLLGAR-----------------------TLQAPEGALGVVGAEEEEGAEEDE 59

  Fly   191 EKWFPALVVAPTAQATVRIRVKDEYLVRSFKDGRYYTVPKKEATEFTREVASKQDVPAVQAALEF 255
            |...|.              |::|...:|....|....|..::             |.:|
  Rat    60 EGETPL--------------VEEETAEQSHPGARCPNSPSGQS-------------PGIQ----- 92

  Fly   256 LDSSVLPAHWDRDSLFGLTNISSDDEGEIDSDSSDDEPHEEKDRFVAQLYKYMDDRGTPLNKVPS 320
                  |..|..:..|       ....|:|:|       .::..|:..|:.:|..||||:|:||.
  Rat    93 ------PHEWTYEEQF-------KQLYELDAD-------PKRKEFLDDLFSFMQKRGTPVNRVPI 137

  Fly   321 ILSRDVDLYRLFRAVQKRGGYNRVTSQNQWKLIAMRLGFTPCTVSVMNLVKQAYKKFLQPYGDFH 385
            :..:.:|||.|||.|..:||...|.::..|:.:...|.......|....::..|.|:|.||....
  Rat   138 MAKQVLDLYALFRLVTAKGGLVEVINRKVWREVTRGLSLPTTITSAAFTLRTQYMKYLYPYECET 202

  Fly   386 RKLGC-SMLMTSRNSNRSKGR----SLVRANSVASPKPMETMKTETISKLAQPNQTNVVASTSSS 445
            |.|.. ..|..:.:|||.:||    :.|...::|.|.|.......:....|.....|...||..|
  Rat   203 RALSSPGELQAAIDSNRREGRRQAYTTVPLFNLAGPTPRGAPGPASSHGPAPTTTPNCPGSTQGS 267

  Fly   446 AAAASVAASSTPARAVSTASQSAA--EESG---------------NTSESSVVVEPPKKQR--KG 491
                   ||..||.|.:..|.|..  ||||               ...|.....|||:|:.  .|
  Rat   268 -------ASGLPAHACAQLSPSPVKKEESGIPPPRLAIPVGLALEAAREKLAPEEPPEKRAVLMG 325

  Fly   492 SAASSQQGKVKSLVEKYEEKSTAVQATSSGTVAGSGASASAAAM 535
            .....:.|...|.:.:.:......:......:||||.|:...|:
  Rat   326 PMDPPRLGATPSFLPRGKAPLREERLDGPLNLAGSGISSINMAL 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
htk	NP_573330.3	RBB1NT	171..262	CDD:285392	15/90 (17%)
		ARID	299..381	CDD:279697	26/81 (32%)
		Tudor-knot	692..751	CDD:288553
Arid3c	NP_001167452.1	BRIGHT	112..203	CDD:128777	28/90 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2744
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810