Protein Alignment htk and Arid3b

DIOPT Version :10

• Sequence 1: NP_573330.3
• Gene: htk / 32877
• FlyBaseID: FBgn0085451
• Length: 2486
• Species: Drosophila melanogaster
• Sequence 2: NP_001102471.1
• Gene: Arid3b / 367092
• RGDID: 1306335
• Length: 565
• Species: Rattus norvegicus
• Alignment Length: 613
• Identity: 135/613 - (22%)
• Similarity: 233/613 - (38%)
• Gaps: 163/613 - (26%)

  Fly   113 KSGRHFNESETL---------DQLPLTHPEHFGNPVVG--GR--------RGRRRGHLNEDSSE- 157
            |.|.|..|::.|         ..|.:|.....|:||:|  ||        |...:.::|.:..|
  Rat    23 KQGSHTREAQFLYAPKLGTQPALLSVTPGRPSGSPVLGPLGRVLPATPAARVSEQSNVNSEPEEE 87

  Fly   158 ------DDDESDAKEVVNEKEENIGKVVCVETESKKKDKEKWFPALVVAPTAQATVRIRVKDEYL 216
                  :|.:.|..||..::.:...|...::..::::.:.....:|:.||...
  Rat    88 EGGLEDEDGDDDVTEVAEKEAQAASKYFHMQKATRQEPRAAPMSSLLPAPGLP------------ 140

  Fly   217 VRSFKDGRYYTVPKKEATEFTREVASKQDVPAVQAALEFLDSSVLPAHWDRDSLF---GLTNISS 278
                        |:.:..|...:.|||.. |:|..|.:       |: |:.|...   |....|.
  Rat   141 ------------PQGQTKEDHTKDASKAP-PSVPTAGQ-------PS-WNLDEQLKQNGALAWSD 184

  Fly   279 DDEG----EIDSDSS-----DDEPHEEKDRFVAQLYKYMDDRGTPLNKVPSILSRDVDLYRLFRA 334
            |.:|    ||..|.:     |.:|  |:..|:..|:.:|..||||:|::|.:..:.:|||.|::.
  Rat   185 DADGGRGREISRDFAKLYELDGDP--ERKEFLDDLFIFMQKRGTPINRIPIMAKQILDLYMLYKL 247

  Fly   335 VQKRGGYNRVTSQNQWKLIAMRLGFTPCTVSVMNLVKQAYKKFLQPYGDFHRKLGC-SMLMTSRN 398
            |.::||...:.::..|:.|...|.......|....::..|.|:|..|....:.|.. :.|..:.:
  Rat   248 VTEKGGLVEIINKKIWREITKGLNLPTSITSAAFTLRTQYMKYLYAYECEKKALSSPAELQAAID 312

  Fly   399 SNRSKGRSLVRANSVASPKPMETMKTETISKLAQPNQTNVVASTSSSAAAASVAASSTPA----R 459
            .||.:||....::|:....|.                  ..|:.:::|||||.|::..||    .
  Rat   313 GNRREGRRPSYSSSLFGYSPA------------------AAAAAAAAAAAASAASAGAPALLSPP 359

  Fly   460 AVSTASQSAAEESGNTSESSVVVEPPKKQRKGSA-------------------ASSQQGKVKSLV 505
            .:..:.......|| |:.||..:.|....|||..                   |.::.|.::.|.
  Rat   360 KIRFSILGLGSSSG-TNTSSPRIPPASTLRKGDGVPVPVPNRLAVSGPLAGQQAGNRTGTLEQLR 423

  Fly   506 EKY------EEKSTAVQATSSGTVAGS---GASASAAAMP------------TTSAAASTATNLS 549
            |:.      |:|::.:.......|..:   ...:.|..:|            .||||   |.||:
  Rat   424 ERLESGEPPEKKASRLSEEEQRLVQQAFQRNLFSMARQLPMKIRINGREDRAETSAA---ALNLT 485

  Fly   550 SATSGGSATIATTAMNKDAESD------LPLAKIKAAAVAAASTRHSMEKETNISSGSSASASSK 608
            ::..|        ::|...:.|      :..|:.....:.|.|...|:        |||||:||.
  Rat   486 TSNIG--------SINMSVDIDGITYTGVLFAQKPVVHLIAGSAPQSI--------GSSASSSSS 534

  Fly   609 ANSAEMQRSRDASP-SVAAPPSAGASTS 635
            ::|:........|| |....|||..|||
  Rat   535 SSSSSSSSHCSPSPTSSRGTPSAEPSTS 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
htk	NP_573330.3	Tudor_ARID4_rpt1	10..60	CDD:410460
		Tudor_ARID4_rpt2	65..118	CDD:410461	2/4 (50%)
		RBB1NT	170..263	CDD:462390	12/92 (13%)
		ARID	296..381	CDD:460187	24/84 (29%)
		CBD_RBP1_like	698..758	CDD:350843
Arid3b	NP_001102471.1	ARID_ARID3B	196..321	CDD:350643	34/126 (27%)