DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment htk and Msl3

DIOPT Version :9

Sequence 1:	NP_573330.3	Gene:	htk / 32877	FlyBaseID:	FBgn0085451	Length:	2486	Species:	Drosophila melanogaster
Sequence 2:	XP_008771391.2	Gene:	Msl3 / 317464	RGDID:	1549763	Length:	531	Species:	Rattus norvegicus

Alignment Length:	485	Identity:	89/485 - (18%)
Similarity:	157/485 - (32%)	Gaps:	127/485 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   698 LKVNYHE-------KKSPSSHGSTYEAKVIEISV-----QRGVPMYLVHYTGWN-NRYDEWVPRE 749
            :|..:|.       :..|:.....|:||:|::.:     .|.:|.||:|:.||| :.:|.|...:
  Rat     7 MKFQFHSGEKVLCFEPDPTKARVLYDAKIIDVIIGKDEKGRKIPEYLIHFNGWNSSSWDRWAAED 71

  Fly   750 RIAENLTKGSKQKTRTISTSSANSGSGGGGGGGGGGGGGGGGGGGSLLVQGSQPPGVSDKQPGKD 814
            .:..:..:..:.:.:....:.|.                         ::|:.......:.||.|
  Rat    72 HVLHDTDENRRLQRKLAKKAIAR-------------------------LRGTGKKKRRCRLPGVD 111

  Fly   815 GCSKMSP------SSGNSTGPGAPSLSGSLGGASSTPSLLSTVVKTPPTGGAKRG---RGRSDSM 870
            ...|..|      :..||.........|...|...........|||.   |.|:.   |.|.| |
  Rat   112 SVLKSVPVKEKTKNDENSISSTCHESCGEKNGGIKEHRQRRIKVKTK---GKKKVLSLRSRKD-M 172

  Fly   871 PPRSTTPSSVVAHSGRTKSPAASQPQLQQ-----QMKKRPTRVVPGTTTPRRVSDASMASESDSD 930
            ..|:.|          .:.|...:.||:.     ..:||..: :|..|....:.::.:...:.:.
  Rat   173 DERTIT----------IEIPEVLKKQLEDDCYYINRRKRLVK-LPCQTNIITILESYVKHFAINA 226

  Fly   931 SDEPVRRPKRQSAKDKPQAGKAQPPGKGR----------LASSASSTAPAA--HPSDDSEEDEEE 983
            :.....||:...|...........|.:..          |..:...|.|..  :|         .
  Rat   227 AFSANERPRHHHAMMHAHMNVHYVPAEKNVDLCKEMVDGLRITFDYTLPLVLLYP---------Y 282

  Fly   984 EEPSAARAASSKQQQQQASSLRGSRAGGNRAMSSGAASAKGRDYDLSEIRSELKGFQPKLLTNAA 1048
            |:....|..|||    ....::.|....||:                  :.||....|.|..:..
  Rat   283 EQTQYKRVTSSK----FFLPIKESTTTTNRS------------------QEELSPSPPLLNPSTP 325

  Fly  1049 SNEERKDLAKKEPSDEPALQDIKK-EPKLESSAKSSSTELSSETESYADEDSQSSDYRKQLKGSG 1112
            .:.|     .:.|:.|||....:| ||:...|.: .||..|:..:..::..|.....|:|...|
  Rat   326 QSTE-----SQPPTGEPATPKRRKAEPEALQSLR-RSTRHSTNCDRLSESSSSPQPKRRQQDTS- 383

  Fly  1113 AGKKEPTASPSKLHHEPVTKRELAVKEEPL 1142
                  |:.|....|   .::.|:|.|.|:
  Rat   384 ------TSMPKLFLH---LEKTLSVTETPV 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
htk	NP_573330.3	RBB1NT	171..262	CDD:285392
		ARID	299..381	CDD:279697
		Tudor-knot	692..751	CDD:288553	17/65 (26%)
Msl3	XP_008771391.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1624495at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010