Protein Alignment htk and cfi-1

DIOPT Version :10

• Sequence 1: NP_573330.3
• Gene: htk / 32877
• FlyBaseID: FBgn0085451
• Length: 2486
• Species: Drosophila melanogaster
• Sequence 2: NP_492644.2
• Gene: cfi-1 / 188793
• WormBaseID: WBGene00000476
• Length: 467
• Species: Caenorhabditis elegans
• Alignment Length: 535
• Identity: 104/535 - (19%)
• Similarity: 166/535 - (31%)
• Gaps: 201/535 - (37%)

  Fly   151 LNEDSSEDDDESDAKEVVNEKEENIGKVVCVETESKKKDKEKWFPALVVAPTAQATVRIRVKDEY 215
            :|.....||..|:..|.|::           :||.:|..     ||     :...|..:.|.|
 Worm    23 VNVGGHHDDSSSNCDERVDD-----------QTEEQKSP-----PA-----SPDLTANLNVFD-- 64

  Fly   216 LVRSFKDGRYYTVPKKEATEFTREVASKQDVPAVQAALEF-LDSSVLPAHWDRDSLF-------- 271
                                    :.|:|.|  ||..|.. |:.|.|.|..:...:|
 Worm    65 ------------------------LESRQKV--VQRLLNSQLNLSNLRAPLNLPPIFQALQGPFS 103

  Fly   272 ----------GLTNISS-----DDEGEIDSDSSD--------------DEPHEE----------- 296
                      |||.||.     |:|.....:..|              :||.|.
 Worm   104 IQQQLLGLASGLTAISPGLDDYDEENTNQGEPEDLTLGGFRKETSVKSEEPSESGINASGPAWSY 168

  Fly   297 KDRFVAQLYKYMDD----------------RGTPLNKVPSILSRDVDLYRLFRAVQKRGGYNRVT 345
            :::| .|||:..||                .|.|:.::|.:..:.:|||.|:|.|.:.||...:.
 Worm   169 EEQF-KQLYELSDDVKRKEWLDDWLNFMHRIGKPVTRIPIMAKQVLDLYELYRLVVQHGGLVEII 232

  Fly   346 SQNQWKLIAMRLGFTPCTVSVMNLVKQAYKKFLQPYGDFHRKL-GCSMLMTSRNSNRSKGRSLVR 409
            ::..|:.|...|.......|....::..|:|:|..|.....|| ..|.|..:.:.||.:...  |
 Worm   233 NKKLWREITKGLNLPSSITSAAFTLRTQYQKYLYDYECEKEKLSNQSDLQQAIDGNRREAPG--R 295

  Fly   410 ANSVASPKPME---------TMKTETISKLAQPN----QTNVVASTSSSAAAASVAASSTPARAV 461
            ..:.:.|.|.:         ||....::.|...|    ..|.::..:|.....|..|..   .|:
 Worm   296 RTAPSFPLPFQLPHAASAAATMLNNQLNGLGMRNDLLDDENTLSLQASGLFGTSYGAEQ---MAI 357

  Fly   462 STASQSAAEESGNTSESSVVVEPPKKQRKGSAASSQQGKVKSLVEKYEEKSTAVQATSSGTVAGS 526
            ..|.|...|.:                         |..|:..|.:.....||....:.|.:..|
 Worm   358 LEAHQRNLERA-------------------------QRAVQQQVARQSLGLTACSNGNGGNIHNS 397

  Fly   527 GASASAAAMPTTSAAASTATNLSSATSGGSATIATTAMNKDAESDLPL--------AKIKAAAVA 583
            |..             ||::|                     :||:|.        .|...|:..
 Worm   398 GRE-------------STSSN---------------------DSDIPAKRPKLENDVKTNGASSM 428

  Fly   584 AASTRHSMEKETNIS 598
            ..||:||...:|::|
 Worm   429 RISTKHSDNSKTSMS 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
htk	NP_573330.3	Tudor_ARID4_rpt1	10..60	CDD:410460
		Tudor_ARID4_rpt2	65..118	CDD:410461
		RBB1NT	170..263	CDD:462390	17/93 (18%)
		ARID	296..381	CDD:460187	24/111 (22%)
		CBD_RBP1_like	698..758	CDD:350843
cfi-1	NP_492644.2	ARID_ARID3	172..289	CDD:350631	29/117 (25%)