Protein Alignment: htk and ARID3A

• Sequence 1: NP_573330.3
• Gene: htk
• FlyBaseID: FBgn0085451
• Length: 2486
• Species: Drosophila melanogaster
• Sequence 2: NP_005215.1
• Gene: ARID3A
• HGNCID: 3031
• Length: 593
• Species: Homo sapiens
• Alignment Length: 812
• Identity: 167/813 (21%)
• Similarity: 263/813 (32%)
• Gaps: 284/813 (35%)

  Fly    54 DAIKAPTGQLRVGAVVEVRHPDRKELVEATITKIQDCSQYTVVFDDGDITTLRRTALCLKSGRHF 118
            |...||.|:.| .|..|.|.|:...:..|.:..               :..:|..|..|  |...
Human    30 DPPAAPPGRAR-AAPDEDREPESARMQRAQMAA---------------LAAMRAAAAGL--GHPA 76

  Fly   119 NESETLDQLPLTHPEHF------GNPVVG-GRRGRRRGHLNEDSSEDDD----------ESDAKE 166
            :...:.|..|.:..|..      |:|  | ||.|....|. ||.:.|:|          |.|..|
Human    77 SPGGSEDGPPGSEEEDAAREGTPGSP--GRGREGPGEEHF-EDMASDEDMKPKWEEEEMEEDLGE 138

  Fly   167 VVNEKEENIGKVVCVETESKKKDKEKWFPALVVAPTAQATVRIRVKDEYLVRSFK-DGRYYTVPK 230
            ...|:||:      .|.|.:::|:|...|.   .|.:..|..:..:.....::|: ||    ||:
Human   139 DEEEEEED------YEDEEEEEDEEGLGPP---GPASLGTTALFPRKAQPPQAFRGDG----VPR 190

  Fly   231 KEATEFTREVASKQDVPAVQAALEFLDSSVLPAHWDRDSLFGLTNISSDDEG------------E 283
                     |...|:.|....|.....:.|.|            .:...|.|            |
Human   191 ---------VLGGQERPGPGPAHPGGAAHVAP------------QLQPPDHGDWTYEEQFKQLYE 234

  Fly   284 IDSDSSDDEPHEEKDRFVAQLYKYMDDRGTPLNKVPSILSRDVDLYRLFRAVQKRGGYNRVTSQN 348
            :|.|       .::..|:..|:.:|..||||:|::|.:..:.:||:.|:..|.::||...|.::.
Human   235 LDGD-------PKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKK 292

  Fly   349 QWKLIAMRLGFTPCTVSVMNLVKQAYKKFLQPYGDFHRKL-GCSMLMTSRNSNRSKGRSLVRANS 412
            .|:.|...|.......|....::..|.|:|.||....|.| ..:.|..:.:|||.:||......|
Human   293 LWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAIDSNRREGRRQSFGGS 357

  Fly   413 VASPKPMETMKTETISKLAQPNQTNVVASTSSSAAAASVAASSTPARAVSTASQSAAEESGNTSE 477
            :.:..|                             ..:....|:|...||:...:|     :|:.
Human   358 LFAYSP-----------------------------GGAHGMLSSPKLPVSSLGLAA-----STNG 388

  Fly   478 SSVVVEPPKKQRKGSAASSQQGKVKSLVEKYEEKSTAVQATSSGTVAGSGASASAAAMPTTSAAA 542
            ||:...|               |:|      :|:.:|:..|..|.:     ..|.|..|..:|
Human   389 SSITPAP---------------KIK------KEEDSAIPITVPGRL-----PVSLAGHPVVAA-- 425

  Fly   543 STATNLSSATSGGSATIATTAMNKDAESDLPLAKIKAAAVAAASTRHSMEKETNISSGSSASASS 607
                                               :||||.||                :|.|:.
Human   426 -----------------------------------QAAAVQAA----------------AAQAAV 439

  Fly   608 KANSAEMQRSRDASPSVAAPPSAGASTSGAAATAQTASNKK-----EKHQRSKQADKEKDKDKEE 667
            .|.:|.:::.|:...| |.||                 .||     ::.||..|...:::.....
Human   440 AAQAAALEQLREKLES-AEPP-----------------EKKMALVADEQQRLMQRALQQNFLAMA 486

  Fly   668 KQASSGKRKKEKISVEKIDTGDFVVGIGDKLKVNYHEKKSPSSHGSTYEAKVIEISVQRGVPMYL 732
            .|.....|...:.|..:.|:...:.|                ::||.        |:...|.:..
Human   487 AQLPMSIRINSQASESRQDSAVNLTG----------------TNGSN--------SISMSVEING 527

  Fly   733 VHYTGWNNRYDEWVPRERIAENLTKGSKQKTRTISTSSANSGSGGGGGGGGGGGGGGGGGGGSLL 797
            :.|||                   ....|......||:.|.|.|||||.....||.||.
Human   528 IMYTG-------------------VLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGN------ 567

  Fly   798 VQGSQPPGVSDKQPGKDGCSKMSPSSGNSTGP 829
                  .|.|..|.|..|.|..|.|:.|::.|
Human   568 ------TGTSGGQAGPAGLSTPSTSTSNNSLP 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
htk	NP_573330.3	RBB1NT	171..262	CDD:285392	19/92 (21%)
		ARID	299..381	CDD:279697	24/82 (29%)
		Tudor-knot	692..751	CDD:288553	8/59 (14%)
ARID3A	NP_005215.1	Acidic	119..156		11/43 (26%)
		BRIGHT	239..331	CDD:128777	26/92 (28%)
		Important for nuclear localization. {ECO:0000250}	445..488		10/61 (16%)
		Homodimerization	490..513		4/39 (10%)
		Important for cytoplasmic localization. {ECO:0000250}	537..557		10/20 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_KOG2744
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R1374
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.930