Protein Alignment: htk and MSL3

• Sequence 1: NP_573330.3
• Gene: htk
• FlyBaseID: FBgn0085451
• Length: 2486
• Species: Drosophila melanogaster
• Sequence 2: NP_523353.2
• Gene: MSL3
• HGNCID: 7370
• Length: 521
• Species: Homo sapiens
• Alignment Length: 463
• Identity: 90/464 (19%)
• Similarity: 150/464 (32%)
• Gaps: 133/464 (29%)

  Fly   695 GDKLKVNYHEK-----KSPSSHGSTYEAKVIEISV-----QRGVPMYLVHYTGWNNRYDEWVPRE 749
            |.|.|.:..||     ..|:.....|:||::::.|     .|.:|.||:|:.|||..:|.|...:
Human     6 GMKFKFHSGEKVLCFEPDPTKARVLYDAKIVDVIVGKDEKGRKIPEYLIHFNGWNRSWDRWAAED 70

  Fly   750 RIAENLTKGSKQKTRTISTSSANSGSGGGGGGGGGGGGGGGGGGGSLLVQGSQPPGVSDKQ---P 811
            .:..: |..:::..|.::..:                           |...:..|...|:   |
Human    71 HVLRD-TDENRRLQRKLARKA---------------------------VARLRSTGRKKKRCRLP 107

  Fly   812 GKDGCSKMSPSSGNSTGPGAPSLSGSLGGASSTPSLLS--------TVVKTPPTGGAKR------ 862
            |.|...|..|:...... ...|||.|...:.:....:|        |.||..|....:|
Human   108 GVDSVLKGLPTEEKDEN-DENSLSSSSDCSENKDEEISEESDIEEKTEVKEEPELQTRREMEERT 171

  Fly   863 ---------------------GRGRSDSMPPRS---TTPSSVVAHSGRTKSPAASQPQLQQQMKK 903
                                 .|.|...:|.::   |...|.|.|.....:.:|::       :.
Human   172 ITIEIPEVLKKQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANE-------RP 229

  Fly   904 RPTRVVPGTTTPRRVSDASMASESDSDSDEPVR------------RPKRQSAKDKPQAGKAQPPG 956
            |...|:|..........|....:...:..:.:|            .|..|:...|..:.|...|
Human   230 RHHHVMPHANMNVHYIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKVTSSKFFLP- 293

  Fly   957 KGRLASSASST-------APAAHPSDDSEEDEEEEEPSAARAASSKQQQQQASSL----RGSRAG 1010
               :..||:||       :|:....:.|.....|.:|:....|:.|:::.:..:|    |.:|..
Human   294 ---IKESATSTNRSQEELSPSPPLLNPSTPQSTESQPTTGEPATPKRRKAEPEALQSLRRSTRHS 355

  Fly  1011 GN---RAMSSGAASAKGRDYDLSEIRSELKGFQPKLLTNAASNEERKDLAKKEPSDEPALQDIKK 1072
            .|   .:.||.:...|.|..|.|       ...|||..:         |.||.|....:...|..
Human   356 ANCDRLSESSASPQPKRRQQDTS-------ASMPKLFLH---------LEKKTPVHSRSSSPIPL 404

  Fly  1073 EPKLESSA 1080
            .|..|.||
Human   405 TPSKEGSA 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
htk	NP_573330.3	RBB1NT	171..262	CDD:285392
		ARID	299..381	CDD:279697
		Tudor-knot	692..751	CDD:288553	20/66 (30%)
MSL3	NP_523353.2	Tudor-knot	14..73	CDD:314560	17/59 (29%)
		MRG	157..506	CDD:310371	52/284 (18%)
		Required for the histone acetyltransferase activity of the MSL complex	290..440		33/144 (23%)
		Microcephalin	309..>413	CDD:315029	28/121 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D1624495at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010