Protein Alignment CG7101 and ZNF729

DIOPT Version :10

• Sequence 1: NP_573329.2
• Gene: CG7101 / 32875
• FlyBaseID: FBgn0030963
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_001229609.1
• Gene: ZNF729 / 100287226
• HGNCID: 32464
• Length: 1252
• Species: Homo sapiens
• Alignment Length: 358
• Identity: 81/358 - (22%)
• Similarity: 132/358 - (36%)
• Gaps: 89/358 - (24%)

  Fly    23 AKKPAKKRTYHCGVCFAEFSRHLAAKRHE-----------QQCSVRV---------------RRL 61
            |:||.|  ...||..|..||   |.::|:           ::|....               ::.
Human   904 AEKPCK--CEECGKAFKHFS---ALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKHKIIHTGKKP 963

  Fly    62 FVCPHCLTLFGEEARLERHRERKHNDGQFLCLQCGKKYASATFLYRHVASWHGQQSLFYCDMCTD 126
            :.|..|...|.:.:.|.||:.....:..:.|.:|||.:.:::.|.:|... |.::.|:.|:.|
Human   964 YKCAECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKDFNNSSTLKKHKLI-HTREKLYKCEEC-- 1025

  Fly   127 NCNDVKTFSGMLELQEH-----AEEVHRLRTLKSTASDADSQVDEMEDLEMLEENIENILPSIDW 186
                ||.|:....|.:|     .|:.::                           .|....:..|
Human  1026 ----VKAFNNFSALMKHKIIHTGEKPYK---------------------------CEECGKAFKW 1059

  Fly   187 DDDLTFGWPTDLDKESCIVNAKPSVFVCPFCANGFPGSLSLVRHLEQVHE-RSALDCCYCGKSHG 250
            ...||         |..:::.......|..|...|....:|.:| :.:|. :....|..|||:..
Human  1060 SSKLT---------EHKVIHTGEKPCKCEECDKAFKHFSALRKH-KVIHTGKKPYQCDECGKAFN 1114

  Fly   251 SREALRSHLQRVHILLRGHVCGICQADFATADHLKKHVNSLHLDHRPHLCPTCGKRFTQRCHLTD 315
            :...|..| :.:|...:.:.|..|...|:.:..|.|| ..:|...:|:.|..|||.|.|..|||.
Human  1115 NSSTLTKH-KIIHTGEKPYKCEECGKAFSQSSILTKH-KIIHSVEKPYKCEECGKAFNQSSHLTR 1177

  Fly   316 H--IKTDRGHGHGTYTCEFCVRPFFRAIDLERH 346
            |  |.|    |...|.||.|.:.|.:...|.||
Human  1178 HKTIHT----GEKPYKCEECGKAFIQCSYLIRH 1206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7101	NP_573329.2	C2H2 Zn finger	242..263	CDD:275368	6/20 (30%)
		C2H2 Zn finger	271..292	CDD:275368	6/20 (30%)
		C2H2 Zn finger	300..319	CDD:275368	11/20 (55%)
		C2H2 Zn finger	330..347	CDD:275368	7/17 (41%)
ZNF729	NP_001229609.1	KRAB	13..73	CDD:214630
		C2H2 Zn finger	182..202	CDD:275368
		C2H2 Zn finger	210..230	CDD:275368
		C2H2 Zn finger	239..258	CDD:275368
		COG5048	262..666	CDD:227381
		C2H2 Zn finger	266..286	CDD:275368
		C2H2 Zn finger	294..314	CDD:275368
		C2H2 Zn finger	322..342	CDD:275368
		C2H2 Zn finger	351..370	CDD:275368
		C2H2 Zn finger	378..398	CDD:275368
		C2H2 Zn finger	406..426	CDD:275368
		C2H2 Zn finger	434..454	CDD:275368
		C2H2 Zn finger	462..482	CDD:275368
		C2H2 Zn finger	490..510	CDD:275368
		C2H2 Zn finger	518..538	CDD:275368
		C2H2 Zn finger	546..566	CDD:275368
		C2H2 Zn finger	574..594	CDD:275368
		C2H2 Zn finger	602..622	CDD:275368
		COG5048	625..1123	CDD:227381	51/268 (19%)
		C2H2 Zn finger	630..650	CDD:275368
		C2H2 Zn finger	658..678	CDD:275368
		C2H2 Zn finger	686..706	CDD:275368
		C2H2 Zn finger	714..734	CDD:275368
		C2H2 Zn finger	742..762	CDD:275368
		C2H2 Zn finger	770..790	CDD:275368
		C2H2 Zn finger	798..818	CDD:275368
		C2H2 Zn finger	826..846	CDD:275368
		C2H2 Zn finger	854..874	CDD:275368
		C2H2 Zn finger	882..902	CDD:275368
		C2H2 Zn finger	910..930	CDD:275368	7/22 (32%)
		C2H2 Zn finger	938..958	CDD:275368	1/19 (5%)
		C2H2 Zn finger	966..986	CDD:275368	6/19 (32%)
		C2H2 Zn finger	994..1014	CDD:275368	6/20 (30%)
		C2H2 Zn finger	1022..1042	CDD:275368	7/25 (28%)
		C2H2 Zn finger	1050..1070	CDD:275368	5/28 (18%)
		C2H2 Zn finger	1078..1098	CDD:275368	5/20 (25%)
		C2H2 Zn finger	1106..1126	CDD:275368	6/20 (30%)
		zf-H2C2_2	1119..1143	CDD:463886	6/24 (25%)
		C2H2 Zn finger	1134..1154	CDD:275368	6/20 (30%)
		C2H2 Zn finger	1162..1182	CDD:275368	10/19 (53%)
		zf-H2C2_2	1174..1199	CDD:463886	12/28 (43%)
		C2H2 Zn finger	1190..1210	CDD:275368	7/17 (41%)