Protein Alignment CG6873 and CFL1

DIOPT Version :10

• Sequence 1: NP_573321.1
• Gene: CG6873 / 32861
• FlyBaseID: FBgn0030951
• Length: 148
• Species: Drosophila melanogaster
• Sequence 2: NP_005498.1
• Gene: CFL1 / 1072
• HGNCID: 1874
• Length: 166
• Species: Homo sapiens
• Alignment Length: 150
• Identity: 40/150 - (26%)
• Similarity: 72/150 - (48%)
• Gaps: 26/150 - (17%)

  Fly     1 MASGINLSRECQHVFE--QIRK------LKQHRYAV----------FVIQDEREIKVEVLGVREA 47
            ||||:.:|.....||.  ::||      :|:.:.||          .::::.:||.|..:|  :.
Human     1 MASGVAVSDGVIKVFNDMKVRKSSTPEEVKKRKKAVLFCLSEDKKNIILEEGKEILVGDVG--QT 63

  Fly    48 NYDDFLADLQRAGSNQCRFAVYDYEYQHQCQGTLSTCLKEKLILMLWCPTLARIKDKMLYSSTFA 112
            ..|.:...::......||:|:||..|:      .....||.|:.:.|.|..|.:|.||:|:|:..
Human    64 VDDPYATFVKMLPDKDCRYALYDATYE------TKESKKEDLVFIFWAPESAPLKSKMIYASSKD 122

  Fly   113 VLKREFPGVQKCIQATEPEE 132
            .:|::..|::..:||...||
Human   123 AIKKKLTGIKHELQANCYEE 142

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6873	NP_573321.1	ADF_cofilin_like	3..142	CDD:200442	37/147 (25%)
CFL1	NP_005498.1	ADF_cofilin_like	3..153	CDD:200442	37/147 (25%)
		Nuclear localization signal. /evidence=ECO:0000255	30..34		1/3 (33%)