DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HisRS and DPB

DIOPT Version :9

Sequence 1:	NP_573305.2	Gene:	HisRS / 32841	FlyBaseID:	FBgn0027087	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_850757.1	Gene:	DPB / 831847	AraportID:	AT5G03415	Length:	385	Species:	Arabidopsis thaliana

Alignment Length:	184	Identity:	35/184 - (19%)
Similarity:	67/184 - (36%)	Gaps:	53/184 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SDTREQILEQIKVQGDLVRQLKAAKESKEKTAPSGGGRVSSSGVPAQRQQQQQ--PQKQQQA--- 61
            |||..|.|..:.:|||                  ..|...:|||..:::.|:.  |.|..:.
plant    60 SDTTFQRLNNLDIQGD------------------DAGSQGASGVKKKKRGQRAAGPDKTGRGLRQ 106

  Fly    62 -------QVQQQQHEQLHQIDEEVARLLALKATLGGDAAPTNQKFTLKTPKGTRDYGPQQMTLRQ 119
                   :|:.:.....:::.:|:....||....|  .:|..|::             .:..:|:
plant   107 FSMKVCEKVESKGRTTYNEVADELVAEFALPNNDG--TSPDQQQY-------------DEKNIRR 156

  Fly   120 GVLDKIVQVFKRHGGEAIDTPVFELKEVLTGKYGEDSKLIYDLKDQGGEILSMR 173
            .|.|.:..:.      |:|....:.||:..  .|.....:.|:::...|.||:|
plant   157 RVYDALNVLM------AMDIISKDKKEIQW--RGLPRTSLSDIEELKNERLSLR 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HisRS	NP_573305.2	S15_NS1_EPRS_RNA-bind	6..92	CDD:294248	17/97 (18%)
		HisS	98..561	CDD:223202	13/76 (17%)
		HisRS-like_core	114..452	CDD:238396	13/60 (22%)
		HisRS_anticodon	467..557	CDD:238436
DPB	NP_850757.1	E2F_TDP	101..182	CDD:280479	14/103 (14%)
		coiled coil	187..233	CDD:271217	5/16 (31%)
		DP	189..>295	CDD:285934	5/14 (36%)
		Neural_ProG_Cyt	276..>320	CDD:284080
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900