Protein Alignment HisRS and hars1

DIOPT Version :10

• Sequence 1: NP_573305.2
• Gene: HisRS / 32841
• FlyBaseID: FBgn0027087
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_031754604.1
• Gene: hars1 / 100489846
• XenbaseID: XB-GENE-6073789
• Length: 515
• Species: Xenopus tropicalis
• Alignment Length: 500
• Identity: 276/500 - (55%)
• Similarity: 357/500 - (71%)
• Gaps: 19/500 - (3%)

  Fly    61 AQVQQQQHEQLHQIDEEVARLLALKATLGGDAAPTNQK-FTLKTPKGTRDYGPQQMTLRQGVLDK 124
            |.|....:...|..|:.     .:.|...|.|.|..|| |.|||||||.|..|:||.:|:.||..
 Frog    22 ACVASVPYRSYHPSDQP-----TIDAVEDGIAQPEVQKHFVLKTPKGTHDVHPKQMAIRERVLST 81

  Fly   125 IVQVFKRHGGEAIDTPVFELKEVLTGKYGEDSKLIYDLKDQGGEILSMRYDLTVPLARYLAMNKI 189
            :|..|||||.|.||||||||||.|||||||||||||||||||||:||:|||||||.||:||||||
 Frog    82 VVNCFKRHGAETIDTPVFELKETLTGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARFLAMNKI 146

  Fly   190 SSIKRYHIAKVYRRDNPAMTKGRYREFYQCDFDIAGTYDPMLPDAECVKIVSEILDTLDIGDYVI 254
            :::|||||.||||||.||  :|||||||||||||||.:|||:|||||:||:.|||..|::|::.|
 Frog   147 TNMKRYHIGKVYRRDKPA--RGRYREFYQCDFDIAGHHDPMIPDAECLKILHEILTELELGNFRI 209

  Fly   255 KLNHRQLLDGMFQACGVPADSFRTICSAVDKLDKSPWADVRKEMVDEKGLDEAAADRIGEYVRLS 319
            |:|.|:||.|:...||||...|||:|:::|||||.||..||:|::::|.|:....::||:|:||:
 Frog   210 KVNDRRLLIGILTVCGVPEAKFRTVCTSIDKLDKIPWDSVRRELIEDKELEAETVEQIGKYIRLN 274

  Fly   320 GGAELVEQLLANEKLKAVPNAVKGLEGMKQLLKYCSIFGLDKRVSFDLSLARGLDYYTGVIYEGV 384
            ||..|:|.|..:.||.....|::||..:|.|.||..|||:..::.:||.||||||||||||||.|
 Frog   275 GGLPLLEHLWDDPKLSQNNLAMEGLRDLKLLNKYSEIFGVTDKIVYDLGLARGLDYYTGVIYEAV 339

  Fly   385 LKGESATVASPAKTS-QQNGEQANEPATVGSVAGGGRYDNLVGMFDPRGKAVPCVGVSIGVERIF 448
            |      :.:|.... :|||....    .||||||||||.|||||||:.:||||||:|||:||:|
 Frog   340 L------LQNPGGPHVRQNGHSEE----YGSVAGGGRYDGLVGMFDPKDRAVPCVGLSIGIERMF 394

  Fly   449 SVLEARAAASGLKLRTSDVEVYVASAHKGLHEQRLKVLNLLWDAGVKAEHSYKLNPKLLVQLQHC 513
            .:||.:...|..|::|:|.:|.|.||.|...|:::|::..||::|::||..||.|||.|.||.:|
 Frog   395 MLLEKKYKNSKEKIQTTDTQVLVVSAQKKFLEEKMKLIAALWNSGIRAEMFYKENPKFLSQLHYC 459

  Fly   514 EEHQIPLVVVLGDAELAQGLVKLREVTTREETNVKLEDLAAEIRR 558
            ||..|||||::|:.||..|:||||.||||||.:|..|::..|||:
 Frog   460 EERGIPLVVIVGEQELQAGVVKLRIVTTREEVSVSKENVIEEIRK 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisRS	NP_573305.2	S15_NS1_EPRS_RNA-bind	6..92	CDD:469733	6/30 (20%)
		PLN02972	<102..559	CDD:215525	264/457 (58%)
hars1	XP_031754604.1	PLN02972	<33..505	CDD:215525	274/488 (56%)