Protein Alignment Frq1 and Ncs1

DIOPT Version :10

• Sequence 1: NP_573271.1
• Gene: Frq1 / 32797
• FlyBaseID: FBgn0030897
• Length: 187
• Species: Drosophila melanogaster
• Sequence 2: NP_077342.1
• Gene: Ncs1 / 65153
• RGDID: 68417
• Length: 190
• Species: Rattus norvegicus
• Alignment Length: 188
• Identity: 134/188 - (71%)
• Similarity: 157/188 - (83%)
• Gaps: 1/188 - (0%)

  Fly     1 MGKKSSKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPQGDPSKFA 65
            |||.:||||.:.::.||..|||||||::||:|||:||||:|.|...||.||||||||.|||:|||
  Rat     1 MGKSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTKFA 65

  Fly    66 SLVFRVFDENNDGSIEFEEFIRALSVTSKGNLDEKLQWAFRLYDVDNDGYITREEMYNIVDAIYQ 130
            :.||.|||||.||.|||.|||:||||||:|.|||||:|||:|||:||||||||.||.:|||||||
  Rat    66 TFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQ 130

  Fly   131 MVGQQPQ-SEDENTPQKRVDKIFDQMDKNHDGKLTLEEFREGSKADPRIVQALSLGGG 187
            |||...: .|:||||:||||:||..||||.||||||:||:|||||||.|||||||..|
  Rat   131 MVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSLYDG 188

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Frq1	NP_573271.1	EFh	39..89	CDD:415501	34/49 (69%)
		FRQ1	<69..173	CDD:444056	77/104 (74%)
Ncs1	NP_077342.1	FRQ1	22..174	CDD:444056	110/151 (73%)
		Ancestral calcium site 1	36..47		6/10 (60%)
		Interaction with IL1RAPL1. /evidence=ECO:0000250|UniProtKB:P62166	174..190		12/15 (80%)