DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spt7 and Supt7l

DIOPT Version :9

Sequence 1:	NP_573248.2	Gene:	Spt7 / 32766	FlyBaseID:	FBgn0030874	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_082426.1	Gene:	Supt7l / 72195	MGIID:	1919445	Length:	412	Species:	Mus musculus

Alignment Length:	357	Identity:	70/357 - (19%)
Similarity:	137/357 - (38%)	Gaps:	75/357 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 HWGSLPAEDDGGQLTPDKY--VPTAAKKLKLDEIRQRGDP---QPQEKHHK----LELRS---AL 57
            :||.:|.  ..||.....:  :|   ::.:|.|:.   ||   ||.....|    |::.|   :|
Mouse     4 YWGEIPI--PSGQTNRSSFDLLP---REFRLVEVH---DPPLHQPSANKPKPPTMLDIPSEPCSL 60

  Fly    58 VTQTIEVMKQTEVLQSLIETYSNKN--------GSSNYLLNPCLMIPEV--DFPP-----ENAAE 107
            ...||::::....|:|||.|...::        ...:..|..|...|.:  |..|     .||..
Mouse    61 TIHTIQLIQHNRRLRSLIATAQTQSQQQTEGVKAEESEPLPSCPGSPPLPDDLQPLDCKNPNAPF 125

  Fly   108 LVGSQKFQKPIWFTPTVDTAYSRGDPEAYPEIPSSACRQAMRKVMCGMLRLAGFTDCSESAVQLL 172
            .:   :...|       ::.:.||..|...|:...:|||.:.:.:..:|...||...:||.::.|
Mouse   126 QI---RHSDP-------ESDFYRGKGEPVTELSWHSCRQLLYQAVATILAHTGFECANESVLETL 180

  Fly   173 TDATEEFLRSFIGEYRGYYDSQPRLQNS---TVLQLVPLERAHFAQTGT-SLTQVHNYYKHKVLA 233
            ||...|:...|....|...|.:..|..:   .|::.|      |.:.|. |:..:..:::|::..
Mouse   181 TDVAHEYCLKFTKLLRFAVDREALLGQTPFPDVMEQV------FHEVGIGSVLSLQKFWQHRIKD 239

  Fly   234 RNRAEIAEFNSVLQEYDKLMKESQSSMQKQHNEFNGHDFLNILDNSATGSSQSIGGMAMGDMLQD 298
            .:...:.....:.:||::::...:::...:..:.....   :.|.:...|.:....:|.||
Mouse   240 YHTYMLQISKQLSEEYERIVNPEKATEDTKPVKIKEEP---VSDITFPVSEELEADLASGD---- 297

  Fly   299 LGGSTGSSGTVSSQQMLYGLLDGQISSNTSNM 330
                         |.:..|:|..|.....||:
Mouse   298 -------------QSLPIGVLGAQSERFPSNL 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spt7	NP_573248.2	None
Supt7l	NP_082426.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	81..107		2/25 (8%)
		TAF9	149..224	CDD:304618	20/80 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	364..412
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28IGQ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR28598
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.960