Protein Alignment CG15814 and RNF121

DIOPT Version :10

• Sequence 1: NP_573247.2
• Gene: CG15814 / 32765
• FlyBaseID: FBgn0030873
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_060790.2
• Gene: RNF121 / 55298
• HGNCID: 21070
• Length: 327
• Species: Homo sapiens
• Alignment Length: 311
• Identity: 186/311 - (59%)
• Similarity: 240/311 - (77%)
• Gaps: 5/311 - (1%)

  Fly    16 KSLDE-----MTPEERMRAQHQLMVEKHRGHDAMHSEMVIILFVTLVIAQIILVEWKKRHYRSYA 75
            :.|||     ::|||:.|.:|..|..|||||:|||:|||:||..|||:||::||:||:||.|||.
Human    17 RELDEVDMSDLSPEEQWRVEHARMHAKHRGHEAMHAEMVLILIATLVVAQLLLVQWKQRHPRSYN 81

  Fly    76 FVTLLAMWLIPLIISCSFGWLRFIIIWLVFTCITALVMRRAISKPIQGTTPRLVYKWFYFIYKLS 140
            .|||..||::||..:....|.||::||::|:.:||.|..||..||:..||||||||||..|||:|
Human    82 MVTLFQMWVVPLYFTVKLHWWRFLVIWILFSAVTAFVTFRATRKPLVQTTPRLVYKWFLLIYKIS 146

  Fly   141 YGLGLVGYLVIIAAFLGMNYMFSQPPNTWMDVGLMFCFYGLYIGVLGRDISEICSDKMAAAIGYY 205
            |..|:|||:.::....|:|.:|...|...||.|:...|||||.|||.||.:|:|:|.||:.||:|
Human   147 YATGIVGYMAVMFTLFGLNLLFKIKPEDAMDFGISLLFYGLYYGVLERDFAEMCADYMASTIGFY 211

  Fly   206 TPQGIPTRHLDQNVCAVCGNQLLVSEKEEGVIENTYKLSCNHVFHEFCIRGWCIVGKKQTCPYCK 270
            :..|:||:||..:||||||.|:.|...|||:|||||:||||||||||||||||||||||||||||
Human   212 SESGMPTKHLSDSVCAVCGQQIFVDVSEEGIIENTYRLSCNHVFHEFCIRGWCIVGKKQTCPYCK 276

  Fly   271 EKVDLQKMFRNPWEKPHVLYGRLLDWIRWLVAWQPLIFFIVQGINWMLGLE 321
            |||||::||.||||:|||:||:||||:|:||||||:|..:|||||::||||
Human   277 EKVDLKRMFSNPWERPHVMYGQLLDWLRYLVAWQPVIIGVVQGINYILGLE 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15814	NP_573247.2	RING-H2_RNF121-like	218..272	CDD:438138	44/53 (83%)
RNF121	NP_060790.2	MFS	<56..212	CDD:475125	79/155 (51%)
		RING-H2_RNF121-like	224..278	CDD:438138	44/53 (83%)