DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stas and TVP38

DIOPT Version :9

Sequence 1:	NP_573225.1	Gene:	stas / 32737	FlyBaseID:	FBgn0030850	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_013014.3	Gene:	TVP38 / 853963	SGDID:	S000001796	Length:	337	Species:	Saccharomyces cerevisiae

Alignment Length:	277	Identity:	55/277 - (19%)
Similarity:	105/277 - (37%)	Gaps:	52/277 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 TPQKQAMSADEKKATK------------KSLVIVAGIFVASLVTMCYVYAIFPELNASEKQHLKI 116
            :|:::.|....|...|            :.::::.||.   |:.|..:..:|.  ||...:.:..
Yeast    67 SPRERLMHNIRKNVQKLQFYFYSLRLWQQIIIVLLGIM---LMIMGILLLVFH--NAILHKVVVT 126

  Fly   117 PRDIQDAKMLAKVLDRYKDMYYFEVMFGVVVAYVFLQTFAIPGSLFLSILLGFLYKFPIALFLIC 181
            ..|:::......:|    .:..|.|.|..::.|..|.|..       .::.|..::..:.|
Yeast   127 SNDLREKMSTHFIL----MVLIFFVAFPPMIGYSLLSTTT-------GLIYGVSFEGWVTL---- 176

  Fly   182 FCSALGATLCYTLSNLVGRRLIRHFWPKKTSEWSKHVEEYRDSL-----FNYMLFLRMTPILPNW 241
               ||| ::..::::.|..:.|.|...:|....::..|.....|     :..:..||:.| .|..
Yeast   177 ---ALG-SVTGSIASFVVFKTILHSRAEKLVHLNRRFEALASILQENNSYWILALLRLCP-FPYS 236

  Fly   242 FINLA-SPVIGVPLHIFALGTFCGVAPPSVIAIQAGKTLQKMTSS----SEAFSWTSMGILMACA 301
            ..|.| :.|.|:.:..|::.... ..|...|.:..|..::.:..|    |..|...|  |::...
Yeast   237 LTNGAIAGVYGISVRNFSIANII-TTPKLFIYLFIGSRVKSLAESESTGSRVFDLVS--IIITLL 298

  Fly   302 CASLLPGLLKNKFKHKK 318
            ..||...||  .||.||
Yeast   299 ILSLTAWLL--YFKTKK 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stas	NP_573225.1	SNARE_assoc	157..276	CDD:286425	22/124 (18%)
TVP38	NP_013014.3	DUF5828	<27..>59	CDD:408916
TVP38	NP_013014.3	TVP38	83..322	CDD:223475	51/261 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0398
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900