Protein Alignment Nprl2 and NPR2

DIOPT Version :8

• Sequence 1: NP_573174.1
• Gene: Nprl2 / 32677
• FlyBaseID: FBgn0030800
• Length: 412
• Species: Drosophila melanogaster
• Sequence 2: NP_010852.4
• Gene: NPR2 / 856647
• SGDID: S000000788
• Length: 615
• Species: Saccharomyces cerevisiae
• Alignment Length: 501
• Identity: 116/502 (23%)
• Similarity: 184/502 (37%)
• Gaps: 158/502 (31%)

  Fly    40 IRCIFLSEFHATAGCKISCQVPDNYISKD--VFDAINVYIIPKQHLQRCILTVNAMDVKIVGYPV 102
            |..||.|.||.|.|.||..:.|.|.:...  .|:....|||||..|...::|......:||.|||
Yeast    11 IHTIFYSVFHPTEGSKIKYEFPPNNLKNHGINFNTFKNYIIPKPILCHKLITFKYGTYRIVCYPV 75

  Fly   103 GIQDQQKYARNAFLFNLCFVCDSRARSVQYEPVVKKLSEYLIMMEEESCFLSRED---------- 157
            .| :...||||.|.||..||......:..|||.:.:|.:...::||::..||:.:
Yeast    76 TI-NSPIYARNFFSFNFVFVFPYDCETSPYEPAITRLGKMFKVLEEQNQLLSKSERDPVFFDLKV 139

  Fly   158 -----------------------------------DKR------------------RLQNIFETV 169
                                               |.|                  .:|::...:
Yeast   140 LENSTTTPSTAGPSSTPNPSSNTTPTHPTSEKDTKDMRSSRYSDLIKDLGLPQSAFSIQDLLMRI 204

  Fly   170 LRDLNERKVATI-VEGDNTIYLKIV-MHKPDPPPVKDHMVPLLLANLRDAPLDNWDLTTQQILPY 232
            .:|||......| ::..|.:.:||. :.:|....|....|||...||:.....|||.|...|:||
Yeast   205 FQDLNNYSECLIPIDEGNAVDIKIFPLLRPPTTCVSLEDVPLSSVNLKKIIDVNWDPTMMSIVPY 269

  Fly   233 INGINHVARIAAEADVETDLVKSCIQNLVYYGVVQLLPILKYSNVYMTQNL-KHLIQSASLSGAC 296
            |:|:|.:|:|:..::.:..||..||::|:||..|.|..|.::||:|...:| ::.:....::..|
Yeast   270 IDGLNSIAKISKLSNSDPGLVIECIRHLIYYKCVTLSDIFQFSNIYAPSSLIRNFLTDPLMASDC 334

  Fly   297 RKYVAL--------------------------------------RPD------------------ 305
            :.||..                                      .||
Yeast   335 QSYVTFPEVSKISNLPLNKSLGSGDQDSPSFSVRRKSKSSSIPSNPDSRTTSFSSTSRVSQNSSL 399

  Fly   306 ------------------------------KTLPSVQRIFQFYASMTHGVTLRAICQR--LCPQH 338
                                          :.||:...:|..|.|::.|.||:...:.  :..:.
Yeast   400 NSSFSSIYKDWRQSQTSCSSSNIHVINNRNRFLPTRSCLFDLYRSLSQGQTLKTWYESKYMILKE 464

  Fly   339 HNIDERRMVIFGLQHRFIRCIHKYPVFTGSVPSGRQKMYTGLISFD 384
            :|||.||.:.|||:.|.|...:.:||.. :..|...|..|.:|:.|
Yeast   465 NNIDIRRFITFGLEKRIIYRCYSFPVMI-NAGSREPKEMTPIITKD 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nprl2	NP_573174.1	NPR3	40..403	CDD:305178	116/502 (23%)
NPR2	NP_010852.4	NPR3	9..490	CDD:305178	110/480 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C187354002
eggNOG	1	0.900				E1_KOG3789
Hieranoid	1	1.000
Homologene	1	1.000				H4771
Inparanoid	1	1.050	106	1.000	Inparanoid score	I1393
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0003867
OrthoInspector	1	1.000				T1136773
orthoMCL	1	0.900				OOG5_129933
Panther	1	1.100			LDO	PTHR12991
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R837
TreeFam	1	0.960
	12	11.780