DRSC/TRiP Functional Genomics Resources

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Protein Alignment Nprl2 and NPRL2

DIOPT Version :10

Sequence 1:NP_573174.1 Gene:Nprl2 / 32677 FlyBaseID:FBgn0030800 Length:412 Species:Drosophila melanogaster
Sequence 2:XP_047303266.1 Gene:NPRL2 / 10641 HGNCID:24969 Length:406 Species:Homo sapiens


Alignment Length:427 Identity:176/427 - (41%)
Similarity:255/427 - (59%) Gaps:38/427 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MHSHTNETAATSTTAGAVTNGAGGSGAGAAGAHGSTEGKIRCIFLSEFHATAGCKIS-C------ 58
            :||.|......|.|.      |.||..|        ...||       |..:.|:|| |      
Human     3 LHSQTTVRLEDSQTQ------APGSQCG--------REDIR-------HIGSVCRISGCRDPVGG 46

  Fly    59 -----QVPDNYISKDVFDAINVYIIPKQHLQRCILTVNAMDVKIVGYPVGIQDQQKYARNAFLFN 118
                 :||:::||:::||.:.||||.|..||..::||.||:.|::|.||.| :.:||:|||.|||
Human    47 FQVPQKVPEDFISRELFDTVQVYIITKPELQNKLITVTAMEKKLIGCPVCI-EHKKYSRNALLFN 110

  Fly   119 LCFVCDSRARSVQYEPVVKKLSEYLIMMEEESCFLSREDDKRRLQNIFETVLRDLNERKVATI-V 182
            |.||||::|::...||:||||:.||..:|.||.|:|.|:.|::|..|...:|.:||.....|: :
Human   111 LGFVCDAQAKTCALEPIVKKLAGYLTTLELESSFVSMEESKQKLVPIMTILLEELNASGRCTLPI 175

  Fly   183 EGDNTIYLKIVMHKPDPPPVKDHMVPLLLANLRDAPLDNWDLTTQQILPYINGINHVARIAAEAD 247
            :..|||:||::..:||||..:::.||:...:..|.....||||||||||||:|..|:.:|:||||
Human   176 DESNTIHLKVIEQRPDPPVAQEYDVPVFTKDKEDFFNSQWDLTTQQILPYIDGFRHIQKISAEAD 240

  Fly   248 VETDLVKSCIQNLVYYGVVQLLPILKYSNVYM-TQNLKHLIQSASLSGACRKYVALRPDKTLPSV 311
            ||.:||:..||||:|||||.|:.||:|||||. |..::.|:...||..||..||..:..|. .|:
Human   241 VELNLVRIAIQNLLYYGVVTLVSILQYSNVYCPTPKVQDLVDDKSLQEACLSYVTKQGHKR-ASL 304

  Fly   312 QRIFQFYASMTHGVTLRAICQRLCPQHHNIDERRMVIFGLQHRFIRCIHKYPV-FTGSVPSGRQK 375
            :.:||.|.|::.|.|:|.:..|...|..::|||:::.|||....||.:.|||| .|....|...:
Human   305 RDVFQLYCSLSPGTTVRDLIGRHPQQLQHVDERKLIQFGLMKNLIRRLQKYPVRVTREEQSHPAR 369

  Fly   376 MYTGLISFDEICCKTGLSPCTIERDIEKDTNVTVIWK 412
            :|||..|:||||||||:|...::..:|.|.|:.:.||
Human   370 LYTGCHSYDEICCKTGMSYHELDERLENDPNIIICWK 406

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Nprl2NP_573174.1 NPR3 40..403 CDD:451662 162/377 (43%)
NPRL2XP_047303266.1 NPR3 43..396 CDD:451662 155/354 (44%)

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