DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sphe and modSP

DIOPT Version :9

Sequence 1:	NP_573148.2	Gene:	sphe / 32648	FlyBaseID:	FBgn0030774	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_536776.2	Gene:	modSP / 42032	FlyBaseID:	FBgn0051217	Length:	628	Species:	Drosophila melanogaster

Alignment Length:	206	Identity:	50/206 - (24%)
Similarity:	80/206 - (38%)	Gaps:	35/206 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 GGEDADATATTFTASLRV-----DNAHVCGGSILSQTKILTTAHCVHRDGKLIDASRLACRVGST 87
            ||...:.|...:...|.|     |....||||:|:...::|.||||:.:|..:..|....||.:.
  Fly   371 GGYTINNTVVPWHVGLYVWHNEKDYHFQCGGSLLTPDLVITAAHCVYDEGTRLPYSYDTFRVIAA 435

  Fly    88 NQYAG-------GKIVNVESVAVHPDY----YNLNNNLAVITLSS--ELTYTDRITAIPLVASGE 139
            ..|..       .|..:|..:.:.|.|    .|...:||::||..  ||::..|...:...:..|
  Fly   436 KFYRNYGETTPEEKRRDVRLIEIAPGYKGRTENYYQDLALLTLDEPFELSHVIRPICVTFASFAE 500

  Fly   140 ALPAEGSEVIV-------AGWGRTSDGTNSYKIRQISLKVAPEATCLDAYSDHDEQSFCLAHELK 197
                  .|.:.       |||    :..|.::::.:.......:.|.....|.....||:..:.|
  Fly   501 ------KESVTDDVQGKFAGW----NIENKHELQFVPAVSKSNSVCRRNLRDIQADKFCIFTQGK 555

  Fly   198 EGTCHGDGGGG 208
            ...|.||.|||
  Fly   556 SLACQGDSGGG 566

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	47/192 (24%)
sphe	NP_573148.2	Tryp_SPc	42..244	CDD:214473	47/192 (24%)
modSP	NP_536776.2	LDLa	27..58	CDD:197566
		LDLa	70..101	CDD:197566
		LDLa	123..157	CDD:197566
		LDLa	167..199	CDD:238060
		CCP	<251..284	CDD:153056
		Sushi	309..354	CDD:278512
		Tryp_SPc	371..616	CDD:214473	50/206 (24%)
		Tryp_SPc	371..591	CDD:304450	50/206 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436914
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930