|
Fly 8 LALEDGTVLPGYSFGYVPSENESKVGFGGEVVFQTGMVGYTEALTDRSYSGQILVLTYPLIGNYG 72
|.|:|||||.||||| ::....||:|||||||||.|::||.||.|||||:||||:||||
Yeast 24 LELKDGTVLQGYSFG-------AEKSVAGELVFQTGMVGYPESVTDPSYEGQILVITYPLVGNYG 81
Fly 73 VP---APDEDEHGLPLHFEWMKGVVQATALVVGEVAEEAFHWRKWKTLPDWLKQHKVPGIQDIDT 134
|| ..||....||.:|| ...:....||:....:|..|:....:|..||:...:|.:..:||
Yeast 82 VPDMHLRDELVEELPRYFE--SNRIHIAGLVISHYTDEYSHYLAKSSLGKWLQNEGIPAVYGVDT 144
Fly 135 RALTKKLREQGSMLGKIVYEKPPVE-GLPKSS----------FVDPNVRNLAKECSVKERQVY-- 186
|:|||.||:.|||||::..||...: .:.:|| :|||||:||..:.|:.|.::|
Yeast 145 RSLTKHLRDAGSMLGRLSLEKSGSDRTISRSSSWRSAFDVPEWVDPNVQNLVSKVSINEPKLYVP 209
Fly 187 ----------GNPNGKGPRIAILDCGLKLNQLRCLLQRGASVTLLPWSARLEDEQFDALFLSNGP 241
..|:||..||..:|.|:|.||:||.::||..:.::||:.....|.:|.||:||||
Yeast 210 PADNKHIELQTGPDGKVLRILAIDVGMKYNQIRCFIKRGVELKVVPWNYDFTKEDYDGLFISNGP 274
Fly 242 GNPESCDQIVQQVRKVIEEGQKPVFGICLGHQLLAKAIGCSTYKMKYGNRGHNLPCLHRATGRCL 306
|:|...|.:.|::..|:|..:.|||||||||||:|:|.|.||.|:|:||||||:||....:|||.
Yeast 275 GDPSVLDDLSQRLSNVLEAKKTPVFGICLGHQLIARAAGASTLKLKFGNRGHNIPCTSTISGRCY 339
Fly 307 MTSQNHGYAVDLEQLPDGWSELFVNANDGTNEGIVHASKPYFSVQFHPEHHAGPQDTEFLFDVFM 371
:||||||:|||::.|..||..|||||||.:||||.|:..||||||||||...||:|||||||||:
Yeast 340 ITSQNHGFAVDVDTLTSGWKPLFVNANDDSNEGIYHSELPYFSVQFHPESTPGPRDTEFLFDVFI 404
Fly 372 ESIQQ-------KDLTIP-QLIEQRLRPTTPAIDSAPVMPRKVLILGSGGLSIGQAGEFDYSGSQ 428
::::: |.:..| .|:|..:: ..|.|:: :|||:||||||||||||||||||||
Yeast 405 QAVKEFKYTQVLKPIAFPGGLLEDNVK-AHPRIEA-----KKVLVLGSGGLSIGQAGEFDYSGSQ 463
Fly 429 AIKAMRESNIQTVLINPNIATVQTSKGMADKCYFLPLTPHYVEQVIKSERPNGVLLTFGGQTALN 493
||||::|..|.|:||||||||:|||||:|||.||:|:|..:|.:||..|||:.:.:||||||||:
Yeast 464 AIKALKEEGIYTILINPNIATIQTSKGLADKVYFVPVTAEFVRKVILHERPDAIYVTFGGQTALS 528
Fly 494 CGVQLERAGVFSKYNVRILGTPIQSIIETEDRKLFAERVNEIGEQVAPSEAVYSVAQALDAASRL 558
.|:.:: ..|....|::|||||.:||.||||:||:..::||.|:.|.|:|..||.:||.|...:
Yeast 529 VGIAMK--DEFEALGVKVLGTPIDTIITTEDRELFSNAIDEINEKCAKSQAANSVDEALAAVKEI 591
Fly 559 GYPVMARAAFSLGGLGSGFANNEEELQSLAQQALAHSSQLIVDKSLKGWKEVEYEVVRDAYNNCI 623
|:||:.|||::||||||||||||:||..|...|.:.|.|::|:||:||||||||||||||::|||
Yeast 592 GFPVIVRAAYALGGLGSGFANNEKELVDLCNVAFSSSPQVLVEKSMKGWKEVEYEVVRDAFDNCI 656
Fly 624 TVCNMENFDPLGIHTGESIVVAPSQTLSDREYQMLRSTALKVIRHFGVVGECNIQYALCPHSEQY 688
||||||||||||||||:||||||||||||.:|.|||:||:.||||.||||||||||||.|.|:.|
Yeast 657 TVCNMENFDPLGIHTGDSIVVAPSQTLSDEDYNMLRTTAVNVIRHLGVVGECNIQYALNPVSKDY 721
Fly 689 YIIEVNARLSRSSALASKATGYPLAYVAAKLALGLPLPDIKNSVTGNTTACFEPSLDYCVVKIPR 753
.|||||||||||||||||||||||||.||||.|.:||.::|||||.:|.|||||||||||||:||
Yeast 722 CIIEVNARLSRSSALASKATGYPLAYTAAKLGLNIPLNEVKNSVTKSTCACFEPSLDYCVVKMPR 786
Fly 754 WDLAKFVRVSKHIGSSMKSVGEVMAIGRNFEEAFQKALRMVDSDVLGF---DPDVVPLNKEQLAE 815
|||.||.|||..:.||||||||||:|||.||||.|||:|..:...||| |.|: .:..
Yeast 787 WDLKKFTRVSTELSSSMKSVGEVMSIGRTFEEAIQKAIRSTEYANLGFNETDLDI------DIDY 845
Fly 816 QLSEPTDRRPFVIAAAL-QLGMSLRELHQLTNIDYWFLEKLERIILLQSLLTRNGSRTD--AALL 877
:|:.|||.|.|.||.|. :.|.|:.::.::|.||.|||.||..::.....::..|::.: :.:|
Yeast 846 ELNNPTDMRVFAIANAFAKKGYSVDKVWEMTRIDKWFLNKLHDLVQFAEKISSFGTKEELPSLVL 910
Fly 878 LKAKRFGFSDKQIAKYIKSTELAVRHQRQEFGIRPHVKQIDTVAGEWPASTNYLYHTYNGSEHDV 942
.:||:.||.|:|||:::.|.|:|:|..|:|:||.|.||||||||.|:||.|||||.|||...||:
Yeast 911 RQAKQLGFDDRQIARFLDSNEVAIRRLRKEYGITPFVKQIDTVAAEFPAYTNYLYMTYNADSHDL 975
Fly 943 DFPGGHTIVVGSGVYRIGSSVEFDWCAVGCLRELRKLQRPTIMINYNPETVSTDYDMCDRLYFEE 1007
.|.....:|:||||||||||||||||||..:|.||.....|||:||||||||||||..||||||.
Yeast 976 SFDDHGVMVLGSGVYRIGSSVEFDWCAVTAVRTLRANNIKTIMVNYNPETVSTDYDEADRLYFET 1040
Fly 1008 ISFEVVMDIYEMENSEGIILSMGGQLPNNIAMDLHRQQAKVLGTSPESIDCAENRFKFSRMLDRK 1072
|:.|.|:||||:|||.|:::|||||..|||||.|||:..|:|||||:.||.||||:|||||||:.
Yeast 1041 INLERVLDIYEIENSSGVVVSMGGQTSNNIAMTLHRENVKILGTSPDMIDSAENRYKFSRMLDQI 1105
Fly 1073 GILQPRWKELTNLQSAIEFCEEVGYPCLVRPSYVLSGAAMNVAYSNQDLETYLNAASEVSREHPV 1137
|:.||.|||||::..|..|.|:||||.||||||||||||||..||..|||:|||.|.||||::||
Yeast 1106 GVDQPAWKELTSMDEAESFAEKVGYPVLVRPSYVLSGAAMNTVYSKNDLESYLNQAVEVSRDYPV 1170
Fly 1138 VISKFLTEAKEIDVDAVASDGRILCMAVSEHVENAGVHSGDATLVTPPQDLNAETLEAIKRITCD 1202
||:|::..||||::||||.:|.::...|||||||||||||||||:.|||||..||::.|...|..
Yeast 1171 VITKYIENAKEIEMDAVARNGELVMHVVSEHVENAGVHSGDATLIVPPQDLAPETVDRIVVATAK 1235
Fly 1203 LASVLDVTGPFNMQLIAKNNELKVIECNVRVSRSFPFVSKTLDHDFVATATRAIVGLDVEPLDVL 1267
:...|.:|||:|:|.|||:||:||||||||.||||||:||.:..:.:..||:||:||.:.|
Yeast 1236 IGKALKITGPYNIQFIAKDNEIKVIECNVRASRSFPFISKVVGVNLIELATKAIMGLPLTP---- 1296
Fly 1268 HGVGK-----VGVKVPQFSFSRLAGADVQLGVEMASTGEVACFGDNRYEAYLKAMMSTGFQIPKN 1327
:.|.| |.||||||||.||||||..||||||||||||.||.::||||||::::|||::||.
Yeast 1297 YPVEKLPDDYVAVKVPQFSFPRLAGADPVLGVEMASTGEVATFGHSKYEAYLKSLLATGFKLPKK 1361
Fly 1328 AVLLSIGSFKHKMELLPSIRDLAKMGYKLYASMGTGDFYAEHGVNVESVQWTFDKTTPDDINGEL 1392
.:||||||:|.|.|||.|::.|..|||||:|:.||.||.:|||: :||:.......||.....
Yeast 1362 NILLSIGSYKEKQELLSSVQKLYNMGYKLFATSGTADFLSEHGI---AVQYLEVLNKDDDDQKSE 1423
Fly 1393 RHLAEFLANKQFDLVINLPMSGGGARRVSSFMTHGYRTRRLAVDYSIPLVTDVKCTKLLVESMRM 1457
..|.:.|||.:.||.|||| |....||.:|:::.||:|||||||||:||||:|||.|||:|::..
Yeast 1424 YSLTQHLANNEIDLYINLP-SANRFRRPASYVSKGYKTRRLAVDYSVPLVTNVKCAKLLIEAISR 1487
Fly 1458 NGGKPPMKTHTDCMTSRRIVKLPGFIDVHVHLREPGATH----KEDFASGTAAALAGGVTLVCAM 1518
|.... .:..|..||.|.:.|||.|::..:: |.|:| ..:....|...|..|.|....|
Yeast 1488 NITLD--VSERDAQTSHRTITLPGLINIATYV--PNASHVIKGPAELKETTRLFLESGFTYCQLM 1548
Fly 1519 PN--TNPSIVDRETFTQFQELAKAGARCDYALYVGASDDNWAQVNELASHACGLKMYLNDTFGTL 1581
|. :.|.|.|..:......:::..:..|::..:..:..|...|.:.||....|.:.|.: |
Yeast 1549 PRSISGPVITDVASLKAANSVSQDSSYTDFSFTIAGTAHNAHSVTQSASKVTALFLPLRE----L 1609
Fly 1582 KLSDMTSWQRHLSHWPKRSPIVCHAERQSTAAVIMLAHLLDRSVHICHVARKEEIQLIRSAKEKG 1646
| :.:|:....|:.||....::..|:....|:|::|..|.:||:||..|:.||::.||.:.|.|.
Yeast 1610 K-NKITAVAELLNQWPTEKQVIAEAKTADLASVLLLTSLQNRSIHITGVSNKEDLALIMTVKAKD 1673
Fly 1647 VKVTCEVCPHHLFLSTKDVERLGHGMSEVRPLLCSPEDQEALWENIDYIDVFATDHAPHTLAEKR 1711
.:|||:|..:.||::..|... ...|.:.||||..|.|:|.||.|:....|..||...
Yeast 1674 PRVTCDVNIYSLFIAQDDYPE--------AVFLPTKEDQEFFWNNLDSIDAFSVGALPVALANVT 1730
Fly 1712 SERPPPGFPGVETILPLLLQAVHEGRLTMEDIKRKFHRNPKIIFNLPDQAQTYVEVDLDEEWTIT 1776
..:...|. |::..|||||.||.||:||::||..:.|.||..|||:|.| .:.||:|||..:
Yeast 1731 GNKVDVGM-GIKDSLPLLLAAVEEGKLTIDDIVLRLHDNPAKIFNIPTQ-DSVVEIDLDYSF--- 1790
Fly 1777 GNEMKSKSGWTPFEGTKVKGRVHRVVLRGEVAFVDGQVLVQPGFGQNVRPKQSPLASEASQDLLP 1841
:....|:|| ...:.|.:.|||..||...:.|: ||.||.........||.:..||.:|
Yeast 1791 ----RRNKRWSPF-NKDMNGGIERVVYNGETLVLSGE-LVSPGAKGKCIVNPSPASITASAEL-- 1847
Fly 1842 SDNDANDTFTRLLTSEGPGGGVHGISTKVHFVDGANFLRPNSPSPRIRLDSASNTTLREY----- 1901
....|...|: :|.|..... :|.|....|..| :.....|:...||.
Yeast 1848 QSTSAKRRFS--ITEEAIADN----------LDAAEDAIPEQP---LEQKLMSSRPPRELVAPGA 1897
Fly 1902 LQRTTNSNPVAHSLMGKHILAVDMFNKDHLNDIFNLAQLLKLRGTKDRPVDELLPGKIMASVFYE 1966
:|....|| :...|:|||::..|.:...:.:|.:||.|:....::..:| |:.|.::.::|:|
Yeast 1898 IQNLIRSN---NPFRGRHILSIKQFKRSDFHVLFAVAQELRAAVAREGVLD-LMKGHVITTIFFE 1958
Fly 1967 VSTRTQCSFAAAMLRLGGRVISMDNITSSVKKGESLEDSIKVVSSYADVVVLRHPSPGAVARAAT 2031
.||||..||.|||.|||||:::::.:.|||||||:|:|:|:.::.|:|.:|:||....:|..||.
Yeast 1959 PSTRTCSSFIAAMERLGGRIVNVNPLVSSVKKGETLQDTIRTLACYSDAIVMRHSEEMSVHIAAK 2023
Fly 2032 FSRKPLINAGDGVGEHPTQALLDIFTIREEFGTVNGLTITMVGDLKNGRTVHSLARLLTLYNVNL 2096
:|..|:||.|:|..||||||.||:||||||.|||||:|:|.:||||:|||||||.|||..|.|.:
Yeast 2024 YSPVPIINGGNGSREHPTQAFLDLFTIREEIGTVNGITVTFMGDLKHGRTVHSLCRLLMHYQVRI 2088
Fly 2097 QYVAPNSLQMPDEVVQFVHQRGVKQLFARDL-KNVLPDTDVLYMTRIQRERFDNVEDYEKCCGHL 2160
..|:|..|::|:.:.:.:.:.|:..:.:.:| .:::..|||||.||:|.|||::.|:|.:.....
Yeast 2089 NLVSPPELRLPEGLREELRKAGLLGVESIELTPHIISKTDVLYCTRVQEERFNSPEEYARLKDTY 2153
Fly 2161 VLTPEHMMRAKKRSIVLHPLPRLNEISREIDSDPRAAYFRQAEYGMYIRMALLAMVVG 2218
::..:.:..||:...::|||||:|||..|:|.|.|||||||.:||:::||||||||:|
Yeast 2154 IVDNKILAHAKENMAIMHPLPRVNEIKEEVDYDHRAAYFRQMKYGLFVRMALLAMVMG 2211
| 
