Protein Alignment: LeuRS and IleRS

• Sequence 1: NP_001285589.1
• Gene: LeuRS
• FlyBaseID: FBgn0284253
• Length: 1182
• Species: Drosophila melanogaster
• Sequence 2: NP_524840.2
• Gene: IleRS
• FlyBaseID: FBgn0027086
• Length: 1229
• Species: Drosophila melanogaster
• Alignment Length: 1403
• Identity: 269/1404 (19%)
• Similarity: 469/1404 (33%)
• Gaps: 475/1404 (34%)

  Fly    19 EREVQQRWEAERVHESDAPTAPKKRQAEKFFVTFPFPYMNGRLHLGHTFSLSKAEYSMRYHRLKG 83
            |..|.|:|..|.:.|..:..:  |.:.:..|...| |:..|..|.||..:.:..:...||...:|
  Fly    23 EENVLQKWRHENIFEKCSQLS--KGKPKYTFYDGP-PFATGLPHYGHILAGTIKDIVTRYAYQQG 84

  Fly    84 RRVLWPFGFHCTGMPIKACADKLTRELEQFGFPPQFPETEEVVPVAAEAASEVPKDKSKGKKSKA 148
            ..|...||:.|.|:|::...|||..                         .:.|:|
  Fly    85 YHVDRRFGWDCHGLPVEFEIDKLLN-------------------------IKGPED--------- 115

  Fly   149 VAKTGAAKYQWQIMQSLGLKDEEIKDFANAEHWLNYFPPLAVQDLKRIGVHVDWRRTFITTDANP 213
            |||.|.|.|..:..:.:         ...|:.|.|.        :.|:|..:|::..:.|  ..|
  Fly   116 VAKMGIAAYNAECRKIV---------MRYADEWENV--------VTRVGRWIDFKNDYKT--LYP 161

  Fly   214 YFDSFVRWQFNHLKERGKIMYGKRYTIYSPKDGQPC------MDHDRSSGEGVGPQEYTLIKMKV 272
            ::...:.|.|..|.::|.:..|.:...||    ..|      .:.:::..|.|.|  ..::.::.
  Fly   162 WYMESIWWIFKQLFDKGLVYQGVKVMPYS----TACTTSLSNFEANQNYKEVVDP--CVVVALEA 220

  Fly   273 LEVPKALSSIKQPIFMVAATLRPETMYGQTNCWLHPDIKYIAWQANKNNEVWVSTRRAARNMTYQ 337
            :.:|..        |.:..|..|.|:.....|.:||.:.|:..:..|::.::|   .|...::|.
  Fly   221 VSLPNT--------FFLVWTTTPWTLPSNFACCVHPTMTYVKVRDVKSDRLFV---LAESRLSYV 274

  Fly   338 GFTAVEGEIK-VLAEVTGQDLLGVPLSAPLTKH----KVVYSLPMLSIKEDKGTGVVTSVPSDSP 397
            ..:..|.|:| .....|.:||...||.....|.    |....|....:.||.|||:|.:.|....
  Fly   275 YKSETEYEVKEKFVGKTLKDLHYKPLFPYFAKRGAEVKAYRVLVDEYVTEDSGTGIVHNAPYFGE 339

  Fly   398 DDY-----AALVDLQKKEAFRQKYGLKDEMVLPYEPIPIIEVPTLGKLSAVHAYETLKIQSQNDK 457
            |||     |.|:             .|...||    .|:.|.   |:.:
  Fly   340 DDYRVCLAAGLI-------------TKSSEVL----CPVDEA---GRFT---------------- 368

  Fly   458 DKLAEAKEMCYLKSFYDGVMLVGAFAGRKIQDVKKDL------QKRLVDANEADVYYEPEKTIMS 516
               .||.:                |.|:.::|..|.:      :..||.:.:....|    ....
  Fly   369 ---NEASD----------------FEGQYVKDSDKQIMAALKARGNLVSSGQVKHSY----PFCW 410

  Fly   517 RSADECVVALCNQWYLNYGEPEWQAQATKIL------HGMETFHEEARNNFEACLNWLHE---YA 572
            ||....:......|::..     :..:..:|      :.:..|.:|.|..     |||.|   :|
  Fly   411 RSDTPLIYKAVPSWFVRV-----EHMSKNLLDCSSQTYWVPDFVKEKRFG-----NWLKEARDWA 465

  Fly   573 CSRTYGLGTKLPWDDKWLIESLSDSTIYMAFYTVVHLLQGGTFRGEKPGPFGIKPSDMTGEIWDY 637
            .||....||.:|   .|...|..::.:..:...:..|             .|::..|:..|..|:
  Fly   466 ISRNRYWGTPIP---IWRSPSGDETVVIGSIKQLAEL-------------SGVQVEDLHRESIDH 514

  Fly   638 I---------------------FFKETPLPKKTAIKQEHLAV-LRREFEYWYPMDLRVSGKDLIQ 680
            |                     :|:...:|    ..|:|... ..::|...:|.|....|.|..:
  Fly   515 IEIPSAVPGNPPLRRIAPVFDCWFESGSMP----FAQQHFPFENEKDFMNNFPADFIAEGIDQTR 575

  Fly   681 NHLTFCLYNHAAIWPNDENKWP-KGMRVNGHLL-LNSAKMSKSDGNFLTLTEAVDKFSADGMRLC 743
            ......|....|::    ||.| |.:..:|.:| .:..||||...|:....|.|.|:.||.:||.
  Fly   576 GWFYTLLVISTALF----NKAPFKNLIASGLVLAADGQKMSKRKKNYPDPMEVVHKYGADALRLY 636

  Fly   744 LADAG-DSVEDANFVESTADAGILRLY--TFIEW---VKEMLENRSSLRKGTDKTFNDQ-VFLSE 801
            |.::. ...|...|.|.    |:..:.  .|:.|   .:.:|:|.....| .|...|.| .:..|
  Fly   637 LINSPVVRAESLRFKEE----GVRDIIKDVFLPWYNAYRFLLQNIVRYEK-EDLAGNGQYTYDRE 696

  Fly   802 LNLKTQQTDENYRK--------MLFKEALRSGF------YEL------------QL----ARDKY 836
            .:||      |..|        :.|||:|...|      |.|            ||    .|...
  Fly   697 RHLK------NMDKASVIDVWILSFKESLLEFFATEMKMYRLYTVVPRLTKFIDQLTNWYVRLNR 755

  Fly   837 RELCGANGMHE-----DLVLEFIRRQALLVSPICPHMAEHVW---------GLLGNKESIVHARW 887
            |.:.|..|..:     |.:.:.:.....:::|..|::.|:::         |.|.:.:|:.:...
  Fly   756 RRIKGELGADQCIQSLDTLYDVLYTMVKMMAPFTPYLTEYIFQRLVLFQPAGTLEHADSVHYQMM 820

  Fly   888 P----------------------EVGAINE--------------VDILCSEYLMEAAHSFR---- 912
            |                      |:|.:..              :.|.....::||..:.:
  Fly   821 PVSQKKFIRNDIERSVALMQSVVELGRVMRDRRTLPVKYPVSEIIAIHKDSQILEAIKTLQDFIL 885

  Fly   913 --LNLKNLL-----------------------QIKG---------KAGKDKSV------------ 931
              ||::.|.                       ::||         ||.:|..:
  Fly   886 SELNVRKLTLSSDKEKYGVTLRAEPDHKALGQRLKGNFKAVMAAIKALRDDEIQKQVSQGYFDIL 950

  Fly   932 ---------------------NVQAAKPNRGLVWVAKTYPPWQCC-------VLDTMKELFNKSQ 968
                                 |.:|...|..||.:..| |..:..       |::.:::|..|:|
  Fly   951 DQRIELDEVRIIYCTSEQVGGNFEAHSDNEVLVLLDMT-PNEELLEEGLAREVINRVQKLKKKAQ 1014

  Fly   969 ALP------------DNKVIAATLQQKAELKKFMKRVMPFAQMIREKVESGKGVAALAVTLEF-- 1019
            .:|            |||.....|:.:|:|.|.:..   :|.:|:..::|           ||
  Fly  1015 LIPTDPVLIFHELAADNKAKQEVLEAQAQLAKVLSN---YASIIKTAIKS-----------EFAP 1065

  Fly  1020 ------DERQVLISNLEYLKNTLDLDVLEIKYTDDPSAPEKTREEVRPGSPFISFSVAPNVSVEL 1078
                  .:::::.|.|      :||..:.:|.|..     .|.|...|..|:::.|:|.::....
  Fly  1066 YSSEQASKKRLIASEL------VDLKGVPLKLTIC-----STEELQLPNLPWLNISLAEDLVPRF 1119

  Fly  1079 TNPIERSSLFQVNTVISEGDTVQSLREKLSKIIGL--------------KTDA----------AT 1119
            .|. .::|||..:.|..|..::.:||.:|..:.||              :|.|          ..
  Fly  1120 GNS-SKASLFLQHNVSKEIISLPTLRSELEHLFGLYGVNFNIYVVDHQKRTTALKSIDENLSGKL 1183

  Fly  1120 LKIWRYEDP-------VLGPRKIPNFEDYKAGKSVLGE 1150
            |.:.|.:|.       .|.|.....|.:..:|||:..|
  Fly  1184 LVLTRSQDAPKLSAGYELSPAPYSKFINQHSGKSIFTE 1221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LeuRS	NP_001285589.1	PLN02959	1..1068	CDD:215518	244/1289 (19%)
		nt_trans	47..>204	CDD:294020	33/157 (21%)
		LeuRS_core	<525..758	CDD:173906	55/267 (21%)
		Anticodon_Ia_Leu_AEc	756..876	CDD:153413	34/170 (20%)
IleRS	NP_524840.2	PLN02882	9..1094	CDD:215477	240/1269 (19%)
		IleRS_core	47..>189	CDD:173909	40/196 (20%)
		IleRS_core	<373..650	CDD:173909	63/331 (19%)
		Anticodon_Ia_Ile_ABEc	650..847	CDD:153415	39/208 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C92013229
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
	1	0.930