Protein Alignment Sk2 and cerk-1

DIOPT Version :10

• Sequence 1: NP_647762.3
• Gene: Sk2 / 326219
• FlyBaseID: FBgn0052484
• Length: 661
• Species: Drosophila melanogaster
• Sequence 2: NP_491977.1
• Gene: cerk-1 / 172423
• WormBaseID: WBGene00020398
• Length: 549
• Species: Caenorhabditis elegans
• Alignment Length: 685
• Identity: 144/685 - (21%)
• Similarity: 228/685 - (33%)
• Gaps: 271/685 - (39%)

  Fly    15 SSRATPPGTQDADEGHDVSDTFYTSQRK------KGSHVFRVR-LDATGFTLQRESPGGSIVKEQ 72
            |||:...|    :.||.::|......:|      :..:||..| ||.:.               :
 Worm    35 SSRSRISG----ESGHLIADVQSPHAKKHRIIFDRDHNVFEFRLLDGSA---------------K 80

  Fly    73 HV---RISDIVGARCMRPKKSRRLAMSGACACSSGNPNSPAISASGDHHRPATTPSKCSTNSRDN 134
            |:   |:.:::...|. |.|.:           :|.|               ..|:|.:|:.:.
 Worm    81 HIIVYRLDELLSTTCY-PFKIK-----------NGVP---------------IIPTKPTTSDKT- 117

  Fly   135 IPSDGGDVSAFLYVFAYVLKKRSLRSELHRERTVLTLRFRSFDTFEDNMREADRWYRSLRWQLHR 199
                       || |.:|.||...:           .|.:..........|.|.|:..:...|.|
 Worm   118 -----------LY-FNFVYKKDKQK-----------WRLKQIPVIFYTTSERDYWHSLIDTTLRR 159

  Fly   200 TLEEIFVAPTVDERRRRVLVLLNPKSGSGDAREVFNMHV------TPVLNEAEVPYDLYVTKHSN 258
                      |..|.:.:::.:||..|:|.|:::|..:|      ||.|.     |.:.:|:.:|
 Worm   160 ----------VKNRPKNIIIFINPFGGNGKAQKIFKDNVDAFFWLTPGLR-----YKVVLTERAN 209

  Fly   259 FAIEFLSTRCLDAWCCV---VAVGGDGLFHEIVNGLLQRQDW----------AH-VLPHLALGII 309
            .|.:::.....:.|..:   |:|||||||:|:::|.|.|...          :| |.||:..|||
 Worm   210 HARDYIVEMPPEQWSAIDGLVSVGGDGLFNELLSGALLRTQTDAGRNIDNPSSHLVTPHIRFGII 274

  Fly   310 PCGSGNGLARSIAHCYNEPYFSKPVLGAALTVISGRSSPMDVVRV-QLQSRSLYSFLSIGWGLIS 373
            ..||.|.:. |..|..|:...|      |:.:..|....:||..| |.|.....|..:|.:|.:.
 Worm   275 GAGSANSIV-STVHETNDHATS------AVHIAIGSECNVDVCTVHQHQKLIRISANAISYGWLG 332

  Fly   374 DVDIESERIRMLGYQRFTVWTLYRLVNLRTYNGRISYLLTDHEVSSTHSATGYAAQRRMQSSRSC 438
            ||..:||..|.||..|:. |:.     |||              :..|
 Worm   333 DVLRDSEEYRCLGPIRYQ-WSA-----LRT--------------TIRH----------------- 360

  Fly   439 NTHIDMLNGPAPIYHSSAEYLPQEFADVISLETSINQSFRSRCDSWLSGGSRRSFYYSISESIYH 503
                       |||....::                                         |:.|
 Worm   361 -----------PIYRGMVQF-----------------------------------------SLSH 373

  Fly   504 SLADESEFAGLAAASLENRQQNYGPASELPDLNEPL----------SEDQGWLVEEGEFVMMHAV 558
                               ::|..|..:||...||.          ..|..|          ||.
 Worm   374 -------------------KENVNPKDQLPPCLEPCPVCMKPQGNDKYDYHW----------HAE 409

  Fly   559 YQTHLGIDC-----------HFAPKAQLNDGTIYLILIRAGISRPHLLSFLYN--MSSGTHLPES 610
            : ||: |.|           ..||...:.|||:.|.|: ..|||.|.:.|:..  |..|..|.|.
 Worm   410 F-THV-ICCVIPTVTPFTPYGLAPFTGIGDGTLDLALV-PRISRFHNMQFMRKVAMYGGKQLYEL 471

  Fly   611 HDDHVKVLPVRAFRLEP---YDNHGIITVDGERVE 642
             |..:....|..:..:|   .::.|:..:|||.:|
 Worm   472 -DPSLNCYRVTKWSYQPDADQEDPGVWNLDGEILE 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sk2	NP_647762.3	PLN02958	<213..639	CDD:215517	105/472 (22%)
cerk-1	NP_491977.1	DAGK_cat	<149..505	CDD:445337	111/499 (22%)