DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11583 and BRX1

DIOPT Version :9

Sequence 1:	NP_001033989.1	Gene:	CG11583 / 326206	FlyBaseID:	FBgn0035524	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_014565.2	Gene:	BRX1 / 854078	SGDID:	S000005437	Length:	291	Species:	Saccharomyces cerevisiae

Alignment Length:	285	Identity:	120/285 - (42%)
Similarity:	181/285 - (63%)	Gaps:	24/285 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 RSSDDVVPKKE----KWVNKQRVLVFSARGISHRDRHLMKDIKTLMPHHRPESKMERSKTLSVVN 91
            :|.|:...||:    :::||||.|:.|:||:::|.|||::|:..|:||.|.|.|::..|.|..:|
Yeast    11 KSKDNKSEKKQGNVKQFMNKQRTLLISSRGVNYRHRHLIQDLSGLLPHSRKEPKLDTKKDLQQLN 75

  Fly    92 EMCEMKHCNKAMLFEGRRKRDLYMWISNTSGSTGPSAKFLIENIHTMAELKMTGNCLRGSRPLLS 156
            |:.|:.:||..:.||.|:.:|||:|:|..  ..||:.||.|:|:|||.||..|||||:||||:||
Yeast    76 EIAELYNCNNVLFFEARKHQDLYLWLSKP--PNGPTIKFYIQNLHTMDELNFTGNCLKGSRPVLS 138

  Fly   157 FDSKFDELPHLKLLKELFVQTYSVPNHHPKSQPFVDHVFTFTYLDKRIWFRNFQIL--------- 212
            ||.:|:..||.:|:|||.|..:.||.:..||:||:|||.:|:.:|.:||.|.::|.
Yeast   139 FDQRFESSPHYQLIKELLVHNFGVPPNARKSKPFIDHVMSFSIVDDKIWVRTYEISHSTKNKEEY 203

  Fly   213 ---SEDGGLSEVGPRYVMNPVKIFDGSFTGKTIWENPDYVSPSKQRQVLKKAAKDKYVNR----V 270
               .||..|.|:|||:||..:.|.:|||.|..|:||..||||:..|..:|:.|.::..:|    |
Yeast   204 EDGEEDISLVEIGPRFVMTVILILEGSFGGPKIYENKQYVSPNVVRAQIKQQAAEEAKSRAEAAV 268

  Fly   271 EQKVKHEATRPIRAYDGMDNDELFE 295
            |:|:|....  :.|.|.:.||.||:
Yeast   269 ERKIKRREN--VLAADPLSNDALFK 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11583	NP_001033989.1	Brix	43..290	CDD:294606	112/262 (43%)
BRX1	NP_014565.2	BRX1	1..291	CDD:227483	119/283 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344036
Domainoid	1	1.000	184	1.000	Domainoid score	I686
eggNOG	1	0.900	-	-		E1_COG5154
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10133
Inparanoid	1	1.050	237	1.000	Inparanoid score	I701
Isobase	1	0.950	-	0	Normalized mean entropy	S699
OMA	1	1.010	-	-		QHG54029
OrthoFinder	1	1.000	-	-		FOG0004244
OrthoInspector	1	1.000	-	-		oto99294
orthoMCL	1	0.900	-	-		OOG6_101913
Panther	1	1.100	-	-	LDO	PTHR13634
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R149
SonicParanoid	1	1.000	-	-		X2983
TreeFam	1	0.960	-	-
	16	15.740