DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG32086 and EFHC1

DIOPT Version :8

Sequence 1:NP_729720.1 Gene:CG32086 / 326195 FlyBaseID:FBgn0052086 Length:491 Species:Drosophila melanogaster
Sequence 2:NP_060570.2 Gene:EFHC1 / 114327 HGNCID:16406 Length:640 Species:Homo sapiens

Alignment Length:366 Identity:60/367 (16%)
Similarity:115/367 (31%) Gaps:127/367 (35%)


  Fly    31 KVCLSISNPEELAESLVRRN-YGQINKKSQK-FPAGSVQPSSSIRDLLTSELQKSRFMSF----- 88
            ::.:|...|..:.:.|...| :|.:...:|. |......|...:..:|.::.:..|:::.     
Human   366 RIDVSKREPPPVKQELPPYNGFGLVEDSAQNCFALIPKAPKKDVIKMLVNDNKVLRYLAVLESPI 430

  Fly    89 ---KEKFYEEMYF--------------KKATLGG-------VKKTYSKPEDVTNISQTFGSPSSQ 129
               |::.:...||              ....:||       |.|.||          |..:|...
Human   431 PEDKDRRFVFSYFLATDMISIFEPPVRNSGIIGGKYLGRTKVVKPYS----------TVDNPVYY 485

  Fly   130 SQNECLYDVILPAKSAEQVNKEYEAFHDKYIISHNHYFPSEQVNRRYAQPFDRKSPCGDIHTHGD 194
            ..::.....::            |.|..::||.....:..:.:....||    .||         
Human   486 GPSDFFIGAVI------------EVFGHRFIILDTDEYVLKYMESNAAQ----YSP--------- 525

  Fly   195 FGLKVKRCLEEGENHLKVIGKAQVDFMDRNEAPLGMRNKKYTFAVPDITFGVPLRSNGDVKMLLN 259
                  ..|...:||::           :.|||......|.|...|.:.         :::.|::
Human   526 ------EALASIQNHVR-----------KREAPAPEAESKQTEKDPGVQ---------ELEALID 564

  Fly   260 NIEPCYKTNRLLDAIRYLNKKRHSLRNQLEFHKYALNSVLERSDTDGTGHLPLARILEIFRSFHI 324
            .|:...|.:...|.||.            .|..|         |.:.:|::......:|..|.::
Human   565 TIQKQLKDHSCKDNIRE------------AFQIY---------DKEASGYVDRDMFFKICESLNV 608

  Fly   325 RLD----AQKIRLALSNFRLIVDEGCATERVNYVDFFRLLS 361
            .:|    .:.||:....      ||    ::||.:|.|..|
Human   609 PVDDSLVKELIRMCSHG------EG----KINYYNFVRAFS 639

Known Domains:


GeneSequenceDomainRegion External IDIdentity
CG32086NP_729720.1 None
EFHC1NP_060570.2 Required for its localization in the mitotic spindle and interaction with alpha-tubulin. {ECO:0000269|PubMed:19734894} 1..45
DM10 93..198 CDD:128921
DUF1126 122..153 CDD:284078
DM10 239..359 CDD:128921
DUF1126 263..296 CDD:284078
DM10 416..520 CDD:128921 16/126 (13%)
DUF1126 439..471 CDD:284078 4/32 (13%)
EFh 579..639 CDD:238008 17/91 (19%)
EF-hand_7 579..638 CDD:290234 17/90 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 O PTHR12086
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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