DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32075 and AT5G12220

DIOPT Version :9

Sequence 1:	NP_001246712.1	Gene:	CG32075 / 326192	FlyBaseID:	FBgn0052075	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_196783.2	Gene:	AT5G12220 / 831096	AraportID:	AT5G12220	Length:	611	Species:	Arabidopsis thaliana

Alignment Length:	561	Identity:	132/561 - (23%)
Similarity:	218/561 - (38%)	Gaps:	132/561 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 GKQQKAKVVPVTPPPNVKQRTVVTPWRDTLEFNTTYKWLFGKSNTPATWRQALSKIRIWCLRRGS 83
            |:|.:.|    :.|...||    .||....|:::..:.||  |::|.....||.::..| ..|||
plant    16 GEQDQQK----SSPDGCKQ----VPWLSWEEWDSVRESLF--SSSPDRIASALERVATW-RSRGS 69

  Fly    84 LCPAAVLATSVLVQAHLED-----QEGSAK-------IQDTYASAFTRFYNFMSSIIQGHNMSSM 136
            | ||.|..|..|::..|:|     ::.||.       :|..|.....|..|.:....:.....|:
plant    70 L-PAPVDVTCSLIEIQLKDGFIPREKQSADALYSEHLLQMLYCMGILRLVNCVIEKTRRREDVSI 133

  Fly   137 YETAKELGLQSFIVDLRHLCAHGQELPPVEVLRNTSNHCLEWLRTYYW------LPHMETMSNLD 195
            .:.|:.:|:...::||||..:| :|||.:.|||:.::..||||::|||      :|    :....
plant   134 ADAARAIGIPRKLIDLRHEGSH-RELPALSVLRDAADEALEWLKSYYWEQQKYQIP----LKRDG 193

  Fly   196 AGKLHRKDKLKFEKAVTDLLEIYDLTLECH-------IKGAEKLKAISKLKSSGEFNKIRVYSSS 253
            ...:.|:.|.|..|..      :.|.|:.:       :|.....|.|.|:.||    .:.:|.|
plant   194 TASIRREVKSKLRKLA------FSLQLKRNPQFDSPLVKEKCSNKRIRKIVSS----LVELYPS- 247

  Fly   254 KKAKTSKEILSAVLGDLSALVKKESSSMKDLLDIYTKCLLKMKYFLG----VGLEIDDNEDVIIA 314
                .|.|| |:||  |..|:|...||..  .|:..|.....:.||.    |.:|:.:.|..:
plant   248 ----FSAEI-SSVL--LEFLLKALDSSKS--TDLQNKAGQDFRVFLDEWKPVIMELSNREPEL-- 301

  Fly   315 ATQGLFRLLAVQGYIEKVFLALVQLSENQNESEQRRLGASYWAKKMLETFGMLFRMKRMYKAELD 379
                |..||       |..|.::|.:|.:....::.:......:::...|..|..:....| ...
plant   302 ----LLTLL-------KEVLDMIQNNERRRHETEKPVEEVSQVEQVPFLFAWLVSLLNGSK-HFQ 354

  Fly   380 LNDKLK---PADFATLNTDKISKTMRSLLVHSNADLSVTLIFGDNPKKSRSLIFDRDFIMQRVDA 441
            .|..|:   |:.|       :.:.:|..||.......:.|       ||..|:  .:.:..||..
plant   355 RNSSLEVKPPSIF-------LMELIRRCLVLGALGYELVL-------KSAFLL--AEIVGGRVLK 403

  Fly   442 FSNYSAPIL---KGLLPLADPPYTKTQIEDLTKLCDAQLEEFYEEEAMEEDSSSEESNNL----D 499
            ......|::   ..::||..   :.|.:...|.|.                   |:..||    .
plant   404 EKLIKLPLMHKSSAIVPLKQ---SSTLVTASTTLL-------------------EQEKNLGNAGK 446

  Fly   500 RLERFLEQAAQSKEHTSD--WGVWKLDKHTDWPKCALGVLP 538
            |||....|.::.|...:|  ...|:  |...|..|.:|:||
plant   447 RLEFVKLQLSKKKGIDTDKTGNRWR--KAKTWSPCPIGMLP 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32075	NP_001246712.1	Las1	42..186	CDD:281960	48/161 (30%)
AT5G12220	NP_196783.2	Las1	31..182	CDD:367775	48/155 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	67	1.000	Domainoid score	I3534
eggNOG	1	0.900	-	-		E1_KOG2425
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1070386at2759
OrthoFinder	1	1.000	-	-		FOG0005077
OrthoInspector	1	1.000	-	-		oto3399
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15002
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.010