Protein Alignment scramb1 and Plscr2

DIOPT Version :10

• Sequence 1: NP_648389.3
• Gene: scramb1 / 326186
• FlyBaseID: FBgn0052056
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: XP_006510920.1
• Gene: Plscr2 / 18828
• MGIID: 1270860
• Length: 320
• Species: Mus musculus
• Alignment Length: 367
• Identity: 166/367 - (45%)
• Similarity: 198/367 - (53%)
• Gaps: 65/367 - (17%)

  Fly    48 HPQPPPPTNYGF-MPGPQ-----PAGYAPVPQMPPYG-EAPPYGAGQPPYMGGPGGQPPYAGGPG 105
            ||.|    :.|. |..|:     |||||  ||.||.. :.||...|:|.:.  ...|.|.:|.||
Mouse     5 HPSP----HTGLQMEAPRSGTYLPAGYA--PQYPPAAVQGPPEHTGRPTFQ--TNYQVPQSGYPG 61

  Fly   106 GQPPYVGGPGGQPHYGGGAPPPQAFGGYPPGPAGPGGPPNAFGGYPPGQPQQPIV---TQPGMGP 167
            .|..|.....|...|.....|.                          |..|.||   ||
Mouse    62 PQASYTVSTSGHEGYAATRLPI--------------------------QNNQTIVLANTQ----- 95

  Fly   168 GMGPGMAPQGGPAGDWMSIPTGIPNCPRGLEYLTTIDQLLVKQKVELLEAFTGFETNNKFTIKNA 232
                           ||..|..|.|||.|||||..|||||:.|:|||||..|||||||||.|||:
Mouse    96 ---------------WMPAPPPILNCPPGLEYLNQIDQLLIHQQVELLEVLTGFETNNKFEIKNS 145

  Fly   233 LGQKVYFAAEDNDCCTRNCCGPARPFDMRVFDNFQQEVIHMHRPLACSSCLFPCCLQSIEVSAPP 297
            |||.||.|.||.||||||||..:|||.:|:.|:..|||:.:.|||.||||.||||||.||:.|||
Mouse   146 LGQMVYVAVEDTDCCTRNCCEASRPFTLRILDHLGQEVMTLERPLKCSSCCFPCCLQEIEIQAPP 210

  Fly   298 GNVIGTIEQEWSICSPSFRILNHVGDTVMRIEGPFCTFSLCGDVEFNVVSLTG-EKIGKISKQWS 361
            |..||.:.|.|..|.|...:.|...:.|:::.||....:.|.|::|.:.||.. .:||||:||||
Mouse   211 GVPIGYVTQTWHPCLPKLTLQNDKRENVLKVVGPCVACTCCSDIDFEIKSLDEVTRIGKITKQWS 275

  Fly   362 GLAREIFTDADFFGINFPLDLDVRMKAVLLGATFLIDAMFFE 403
            |..:|.|||:|.|||.|||||:|:||||.|||.||||.||||
Mouse   276 GCVKEAFTDSDNFGIQFPLDLEVKMKAVTLGACFLIDYMFFE 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scramb1	NP_648389.3	PHA03378	<12..187	CDD:223065	37/148 (25%)
		Scramblase	184..404	CDD:252175	130/221 (59%)
Plscr2	XP_006510920.1	Scramblase	97..317	CDD:252175	128/219 (58%)