Protein Alignment CG32052 and Smpdl3a

DIOPT Version :10

• Sequence 1: NP_729555.4
• Gene: CG32052 / 326184
• FlyBaseID: FBgn0044328
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001005539.1
• Gene: Smpdl3a / 294422
• RGDID: 1359277
• Length: 445
• Species: Rattus norvegicus
• Alignment Length: 473
• Identity: 149/473 - (31%)
• Similarity: 234/473 - (49%)
• Gaps: 59/473 - (12%)

  Fly     6 ISWL---GFLLAYSGLPGAQARIGYFWHISDLHLDTLYSTQGDIYRSCWELARSVSGSNANSAAS 67
            ::||   |..:..:...||.| :|.|||::|||||..|....|..:.|    .|..|:|.::
  Rat    13 VAWLCDPGLGVPLAPAYGAPA-VGQFWHVTDLHLDPTYHITDDHTKVC----ASSKGANVSN--- 69

  Fly    68 EPPGPFGHYNCDSPWRLIESAVKTMKAKQGDNVEFVLWTGDALSH-SAQPLSEQKQHEILRNITE 131
              |||||...||||::||.||...:| ..|....|::||||:..| ..:.||.....|::.|:|.
  Rat    70 --PGPFGDVLCDSPYQLILSAFDFIK-NSGQEASFMIWTGDSPPHVPVRELSTGSVIEVITNMTV 131

  Fly   132 LLGRSFSSQFIFPVLGHED----------GSGSYRRLGELWRHWLPSEALVTFDQGGYYSIEQTK 186
            .:...|.:..:||.||:.|          .|..|..:.:||:.||..||:.|..:||:|| ::..
  Rat   132 TVQNLFPNLQVFPALGNHDYWPQDQLPIATSKVYSAVSDLWKPWLDEEAISTLRKGGFYS-QKVA 195

  Fly   187 SR--LRIVALNTNFMRLDPDPDPRASLSLRWPAEYFAEPKASVSSISAEDELLAEQQWLWLEEVL 249
            |.  |||::||||.                    |:.   .::.:::..|   ...|:.|||..|
  Rat   196 SNPDLRIISLNTNL--------------------YYG---PNIMTLNKTD---PANQFEWLENTL 234

  Fly   250 TKSKEKQETVYIVGHMPPGVDERHLGTQHNQLTFTERNNQRYLDMVRRFAPVIQGQFFGHLHSDT 314
            ..|...:|.||::.|:|.|    :|..........:..|::.:|:.||::.||.|||:||.|.|:
  Rat   235 NSSLRNKEKVYVIAHVPVG----YLPYATKTPAMRQYYNEKLVDIFRRYSSVIAGQFYGHTHRDS 295

  Fly   315 FRLIYDAKGNPISWLMIAPSIVPRKAGI-GSSNNPALRLYKFDTGSGQVLDYTQFWLDLPLANRA 378
            ..::.|..||||:.:.:||::.|.|..: ..:|||.:||:::..|...:||..|::|:|..||..
  Rat   296 LMVLSDKNGNPINSVFVAPAVTPVKGVLEKETNNPGVRLFQYKPGDYTLLDMLQYYLNLTEANLK 360

  Fly   379 NEPTWQPEYNLTHYYALPEISAVALHNFAERFTGTDLSWFTRYHRANAVRYHSGSACPGLCMLNH 443
            .|..|..||.||..|.:.::...:||..|::....|...|.:|:....|.|.|.:.|...|....
  Rat   361 GESNWTLEYTLTQAYGVADLQPKSLHGLAQQLATIDSKQFLKYYHYFFVSYDSSAPCDQRCKTLQ 425

  Fly   444 YCAITRLDYDEFRICLEK 461
            .|||..||...:..||::
  Rat   426 ICAIMNLDLVSYEDCLKR 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32052	NP_729555.4	MPP_ASMase	28..351	CDD:277321	107/336 (32%)
		ASMase_C	324..462	CDD:466022	45/139 (32%)
Smpdl3a	NP_001005539.1	MPP_ASMase	37..333	CDD:277321	107/336 (32%)
		ASMase_C	305..444	CDD:466022	45/139 (32%)