DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31937 and YDL114W

DIOPT Version :9

Sequence 1:	NP_608616.2	Gene:	CG31937 / 326177	FlyBaseID:	FBgn0031360	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_010169.1	Gene:	YDL114W / 851444	SGDID:	S000002272	Length:	308	Species:	Saccharomyces cerevisiae

Alignment Length:	213	Identity:	50/213 - (23%)
Similarity:	91/213 - (42%)	Gaps:	36/213 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 ITGASSGIGRALALSLARHGVKLVLS-ARRLEQLEQVQEECLAAARGLLATKDVLVIQMDMLDLD 114
            |||.|||:|..||..|:|...|:::: .:......||:            ..::...|.|:..||
Yeast    43 ITGGSSGLGFELAKELSRRINKVIVADIQSFPTFAQVE------------YNNIFYYQCDITSLD 95

  Fly   115 EHKTHLNTVLNHFHRLDVLVNNAGRS---QRASWTEVEIEVDRELFELDVFAVVHLSRLVVRYFV 176
            |.|.....:......:::::||||.:   :....|..|:|   :|.::::.....    ::..|.
Yeast    96 EIKNLKKAIERDHGNINIIINNAGVAHIKKLEHMTNKEVE---QLIDINLIGAYR----IISTFA 153

  Fly   177 EQ--NGGRGHIAATSSIAG-FSPVPFSPTYCAAKHA-------LNAYLLSLKVEMRKLDVS--LF 229
            |.  :...|.|...:|:.| .:|...: :|.|:|.|       ::.:..||..|..|..:.  |.
Yeast   154 EDMIDNREGFIINIASVLGELTPARLT-SYGASKGAMIGFHKCMSRHFRSLSTECNKTGIKTLLV 217

  Fly   230 APGPIATDFLQEAFTGSQ 247
            .||.|.|:...:..|.|:
Yeast   218 CPGKIKTNMFIDVPTPSK 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31937	NP_608616.2	NADB_Rossmann	44..293	CDD:304358	50/213 (23%)
CG31937	NP_608616.2	adh_short	47..245	CDD:278532	48/209 (23%)
YDL114W	NP_010169.1	17beta-HSDXI-like_SDR_c	40..282	CDD:187598	50/213 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910